Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   EL115_RS06910 Genome accession   NZ_LR134307
Coordinates   1391118..1391807 (-) Length   229 a.a.
NCBI ID   WP_022526966.1    Uniprot ID   -
Organism   Streptococcus milleri strain NCTC10708     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1386118..1396807
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL115_RS06895 (NCTC10708_01375) nrdR 1387229..1387702 (-) 474 WP_022526962.1 transcriptional regulator NrdR -
  EL115_RS06900 (NCTC10708_01376) - 1387885..1388700 (-) 816 WP_126441618.1 endonuclease/exonuclease/phosphatase family protein -
  EL115_RS06905 (NCTC10708_01377) - 1388717..1390906 (-) 2190 WP_126441620.1 PTS transporter subunit IIBC -
  EL115_RS06910 (NCTC10708_01378) covR 1391118..1391807 (-) 690 WP_022526966.1 response regulator transcription factor Regulator
  EL115_RS06915 (NCTC10708_01379) gndA 1391816..1393240 (-) 1425 WP_059221018.1 NADP-dependent phosphogluconate dehydrogenase -
  EL115_RS06920 (NCTC10708_01380) - 1393445..1394110 (+) 666 WP_018370761.1 TetR/AcrR family transcriptional regulator -
  EL115_RS06925 (NCTC10708_01381) - 1394100..1394834 (+) 735 WP_003029928.1 ABC transporter ATP-binding protein -
  EL115_RS06930 (NCTC10708_01382) - 1394818..1395546 (+) 729 WP_018370762.1 ABC transporter permease -
  EL115_RS06935 (NCTC10708_01383) - 1395546..1395773 (+) 228 WP_003029926.1 hypothetical protein -
  EL115_RS06940 (NCTC10708_01384) - 1396045..1396584 (-) 540 WP_018370764.1 DUF177 domain-containing protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26500.61 Da        Isoelectric Point: 6.2732

>NTDB_id=1120897 EL115_RS06910 WP_022526966.1 1391118..1391807(-) (covR) [Streptococcus milleri strain NCTC10708]
MAKRILLVEKEKKLAQFIGLELQKEGYRVDLFETGKDALASARANQYDLFLLNFMLDDMTGTEFAAQLSVIKPASVIIVL
DNRDNILQYTEEIQRFAVAYMVEPFIVTDLVEKISAIFRGRDFIDQHCSQMKVPTSYRNLRIDVQNHTVYRGEEVIALTR
REYDLLATLMGSHQALSREQLLERVWKYEGAVETNVVDVYIRYLRSKIDIVGQKSYIKTVRGVGYVMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=1120897 EL115_RS06910 WP_022526966.1 1391118..1391807(-) (covR) [Streptococcus milleri strain NCTC10708]
ATGGCGAAGCGGATTTTATTAGTTGAGAAAGAAAAAAAATTAGCGCAATTTATTGGCTTAGAGCTACAAAAAGAAGGTTA
TCGAGTTGATCTTTTTGAAACAGGAAAAGATGCTTTGGCGTCTGCGAGAGCTAATCAATACGATTTATTCCTGTTGAATT
TTATGCTTGACGATATGACAGGAACAGAATTTGCCGCACAATTAAGTGTGATAAAGCCTGCTTCGGTCATCATTGTATTG
GATAATCGTGATAATATTCTTCAATATACTGAGGAAATCCAACGCTTTGCTGTTGCTTACATGGTAGAACCATTCATTGT
GACGGACTTAGTTGAAAAAATTTCTGCCATTTTTCGTGGGCGTGATTTTATTGACCAGCATTGTAGTCAGATGAAAGTTC
CAACATCTTATCGGAATCTTCGGATTGATGTGCAAAATCATACAGTTTATCGAGGTGAAGAAGTGATTGCTTTGACTCGA
AGAGAGTATGATTTATTAGCAACATTGATGGGAAGTCATCAGGCTTTAAGCCGTGAACAGTTGTTAGAACGCGTGTGGAA
ATACGAAGGAGCTGTTGAAACAAATGTTGTCGATGTTTATATTCGCTATCTTCGTAGTAAAATTGATATAGTGGGGCAAA
AAAGTTATATAAAAACCGTGCGTGGTGTTGGTTATGTTATGCAAGAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-227)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.696

100

0.489
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.852

100

0.459

Multiple sequence alignment