Detailed information NTG1120890

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: EL115_RS05075
• Genome accession: NZ_LR134307
• Coordinates: 1020518..1021750 (-)
• Length: 410 a.a.
• NCBI ID: WP_003068865.1
• Uniprot ID: A0AAD2SY77
• Organism: Streptococcus milleri strain NCTC10708
• Function: require for competence development (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
Prophage	1011457..1023613	1020518..1021750	within	0

Gene organization within MGE regions

Location: 1011457..1023613

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL115_RS05040 (NCTC10708_01016)	-	1011457..1012197 (+)	741	WP_126441434.1	amino acid ABC transporter ATP-binding protein	-
EL115_RS05045 (NCTC10708_01017)	-	1012573..1014108 (+)	1536	WP_126441435.1	ATP-binding cassette domain-containing protein	-
EL115_RS05050 (NCTC10708_01018)	-	1014226..1015974 (-)	1749	WP_126441436.1	ABC transporter ATP-binding protein	-
EL115_RS05055 (NCTC10708_01019)	-	1015964..1017700 (-)	1737	WP_126441437.1	ABC transporter ATP-binding protein	-
EL115_RS05060 (NCTC10708_01020)	-	1017913..1018710 (-)	798	WP_037596912.1	formate/nitrite transporter family protein	-
EL115_RS05065 (NCTC10708_01021)	-	1018886..1019593 (-)	708	WP_003068871.1	glucosaminidase domain-containing protein	-
EL115_RS05070 (NCTC10708_01022)	yihA	1019918..1020505 (-)	588	WP_003068868.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
EL115_RS05075 (NCTC10708_01023)	clpX	1020518..1021750 (-)	1233	WP_003068865.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
EL115_RS05080 (NCTC10708_01024)	-	1021804..1021977 (-)	174	WP_003024903.1	hypothetical protein	-
EL115_RS05085 (NCTC10708_01025)	-	1021977..1022489 (-)	513	WP_003068862.1	dihydrofolate reductase	-
EL115_RS05090 (NCTC10708_01026)	-	1022774..1023613 (-)	840	WP_126441438.1	thymidylate synthase	-

Sequence

Protein

• Length: 410 a.a.
• Molecular weight: 45677.14 Da
• Isoelectric Point: 4.3940

>NTDB_id=1120890 EL115_RS05075 WP_003068865.1 1020518..1021750(-) (clpX) [Streptococcus milleri strain NCTC10708]
MPTNRTSEMMVYCSFCGKSQEEVQKIIAGNNAFICNECVELAQEIIREELAEEVLADLSEVPKPQELLNILNHYVIGQDR
AKRALAVAVYNHYKRINFHDNREEEDDVELQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
ILLKLLQAADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDT
KNILFIVGGAFDGIEEIVKQRLGEKIIGFGQNNKAIDENSSYMQEIISEDIQKFGLIPELIGRLPVFAALEPLTVDDLVR
ILREPKNALVKQYQTLLSYDDVTLEFDDDALQEIANKAIERKTGARGLRSIIEETMMDVMFEVPSQENVKLVRITKEAVD
GTDKPILETA

Nucleotide

• Length: 1233 bp

>NTDB_id=1120890 EL115_RS05075 WP_003068865.1 1020518..1021750(-) (clpX) [Streptococcus milleri strain NCTC10708]
ATGCCTACAAATCGTACGAGCGAAATGATGGTTTATTGTTCTTTTTGTGGTAAAAGTCAAGAAGAAGTTCAAAAAATTAT
TGCAGGAAACAATGCATTTATTTGTAACGAATGTGTGGAATTAGCACAAGAAATTATTAGAGAAGAATTAGCAGAAGAAG
TCTTGGCAGACTTGTCGGAAGTACCAAAACCACAAGAATTGCTTAACATTTTAAATCACTATGTAATAGGGCAAGATCGT
GCAAAGCGAGCGCTGGCTGTTGCTGTATACAATCACTATAAACGTATCAATTTTCACGATAATCGTGAAGAAGAGGATGA
TGTCGAATTACAAAAATCCAATATTCTTATGATTGGTCCAACTGGTTCTGGTAAGACTTTTCTTGCTCAAACTTTAGCGA
AAAGTCTAAATGTTCCCTTTGCGATTGCAGATGCGACAGCTTTGACGGAAGCTGGCTATGTCGGGGAAGATGTTGAGAAT
ATTCTCTTAAAACTCTTACAGGCGGCAGATTTCAATATTGAACGTGCAGAACGTGGCATTATCTATGTAGATGAGATTGA
CAAAATTGCAAAGAAAAGCGAAAATGTCTCTATTACTCGTGATGTTTCTGGTGAAGGCGTTCAGCAAGCTCTGCTTAAAA
TCATTGAAGGGACTGTAGCTAGTGTACCTCCTCAAGGCGGTCGCAAACATCCACAGCAAGAAATGATTCAAGTGGATACC
AAGAATATTCTTTTTATCGTTGGCGGTGCTTTTGACGGAATCGAAGAAATCGTCAAACAACGTCTAGGTGAAAAGATCAT
TGGTTTTGGTCAAAATAACAAAGCCATTGATGAAAATAGTTCTTATATGCAAGAAATTATTTCCGAAGATATTCAAAAAT
TTGGGCTTATTCCTGAATTGATTGGTCGTTTGCCTGTGTTTGCAGCGCTTGAGCCTTTGACTGTTGATGATTTGGTGCGA
ATTCTCCGTGAGCCTAAGAATGCTTTAGTGAAACAATATCAAACGCTTCTTTCTTATGACGATGTTACATTAGAGTTTGA
TGATGATGCTCTCCAAGAGATTGCTAACAAAGCTATTGAACGCAAGACAGGTGCTCGTGGTTTGCGCTCGATTATCGAAG
AAACCATGATGGATGTCATGTTTGAAGTACCAAGTCAAGAAAATGTGAAGTTAGTGCGGATTACCAAGGAAGCAGTTGAT
GGAACAGATAAACCGATATTAGAAACAGCTTAA

Domains

Predicted by InterproScan.

• ClpX C4-type zinc finger (zf-C4_ClpX) (12-48)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (313-390)

• AAA domain (Cdc48 subfamily) (AAA_2) (111-306)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	86.585	100	0.866
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.458	98.049	0.573