Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   EL097_RS05740 Genome accession   NZ_LR134293
Coordinates   1107979..1109304 (+) Length   441 a.a.
NCBI ID   WP_003044694.1    Uniprot ID   A0AAV3FTH7
Organism   Streptococcus canis strain NCTC12191     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1102979..1114304
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL097_RS05715 (NCTC12191_01123) - 1103634..1104275 (+) 642 WP_003044709.1 response regulator transcription factor -
  EL097_RS05720 (NCTC12191_01124) - 1104312..1105712 (+) 1401 WP_003044706.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  EL097_RS05725 (NCTC12191_01125) - 1105712..1106071 (+) 360 WP_003044703.1 S1 RNA-binding domain-containing protein -
  EL097_RS05730 (NCTC12191_01126) cysK 1106238..1107173 (-) 936 WP_003044700.1 cysteine synthase A -
  EL097_RS05735 (NCTC12191_01127) - 1107291..1107923 (-) 633 WP_003044697.1 YigZ family protein -
  EL097_RS05740 (NCTC12191_01128) comFA/cflA 1107979..1109304 (+) 1326 WP_003044694.1 DEAD/DEAH box helicase Machinery gene
  EL097_RS10890 - 1109519..1109941 (+) 423 WP_003044691.1 ComF family protein -
  EL097_RS05750 (NCTC12191_01130) hpf 1110021..1110569 (+) 549 WP_003044623.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  EL097_RS05755 (NCTC12191_01131) - 1110621..1111574 (-) 954 WP_003044620.1 IS30 family transposase -

Sequence

Protein


Download         Length: 441 a.a.        Molecular weight: 49783.96 Da        Isoelectric Point: 9.8599

>NTDB_id=1120511 EL097_RS05740 WP_003044694.1 1107979..1109304(+) (comFA/cflA) [Streptococcus canis strain NCTC12191]
MEGIENYYGRLFLENQLPEEGKHLAKPLESIVITKGKVTCQRCRYHISEEERLPSGAYYCRFCLVFGRNQSDKSLYYMSP
KPFPKGSCLKWKGQLTPHQKKISQQLVRNVQTKKPTLVHAVTGAGKTEMIYAAIARVIEAGGWVCLASPRVDVCIEVAKR
LSQAFSCQVCLMHAGSSPYQRSPIIVATTHQLLTFYKAFDLLIIDEVDAFPFVTNVQLNHAANQASKTDAARILLTATST
TTLEKQVKRGEVEKLTLARRFHNHPLVIPQFIRSFAILNNIHCHKIPEIVIKYLREQRQTGYPLLIFLPVITTAEIVTNL
LKKAFPKEKIACVSSQAEEREKDITAFRQGEKTILVTTTILERGVTFPGVDVFVLAAHHRVFTPQSLVQISGRVGRSLER
PTGNLYFFHDGISRAMLKARKEIKEMNQKGYPDDMPTVPTT

Nucleotide


Download         Length: 1326 bp        

>NTDB_id=1120511 EL097_RS05740 WP_003044694.1 1107979..1109304(+) (comFA/cflA) [Streptococcus canis strain NCTC12191]
ATGGAAGGTATTGAAAATTATTACGGTCGTTTATTTTTAGAAAATCAATTGCCAGAAGAAGGAAAGCATCTTGCAAAACC
TTTAGAAAGTATAGTAATTACAAAAGGTAAAGTTACTTGCCAACGATGCCGTTATCACATTAGTGAGGAAGAAAGATTGC
CTAGTGGCGCTTATTATTGCCGCTTCTGTCTTGTCTTTGGCCGCAATCAATCTGATAAATCGCTTTACTATATGTCCCCT
AAGCCATTCCCTAAAGGAAGCTGTCTTAAATGGAAAGGACAATTAACACCTCATCAAAAAAAGATTTCCCAACAGTTGGT
AAGAAATGTACAGACCAAAAAGCCTACCTTGGTTCATGCTGTAACAGGAGCTGGTAAAACAGAAATGATTTATGCAGCTA
TTGCAAGAGTTATTGAAGCAGGTGGCTGGGTATGTTTAGCTAGCCCGCGAGTAGATGTTTGTATCGAAGTGGCCAAACGG
TTATCTCAAGCCTTTTCGTGTCAAGTCTGTTTAATGCATGCTGGATCCTCTCCTTACCAGAGAAGTCCTATTATTGTAGC
AACAACACATCAGTTACTCACTTTTTACAAGGCTTTTGACCTTTTGATTATTGATGAAGTTGATGCTTTTCCATTTGTGA
CAAACGTTCAACTGAATCACGCTGCAAATCAAGCCTCTAAAACAGATGCTGCTAGGATTTTATTAACAGCAACATCAACG
ACAACCTTAGAAAAACAAGTCAAAAGAGGAGAAGTAGAAAAGCTAACATTAGCTAGGCGCTTTCATAATCATCCCTTAGT
TATTCCACAGTTTATCAGAAGTTTTGCTATCTTGAACAATATACACTGCCATAAGATTCCTGAAATAGTCATCAAATACC
TTCGAGAGCAGCGGCAGACAGGTTATCCCCTGTTAATATTTCTTCCTGTTATTACAACAGCAGAAATAGTCACCAATTTG
TTAAAAAAAGCTTTTCCAAAAGAAAAGATAGCTTGTGTTTCAAGTCAAGCAGAAGAGAGGGAGAAAGATATTACTGCCTT
TCGCCAGGGTGAAAAAACTATTTTAGTCACGACAACAATCTTGGAAAGGGGGGTTACCTTTCCTGGTGTTGATGTCTTTG
TACTAGCAGCCCACCATCGAGTTTTCACCCCACAAAGTCTTGTTCAAATCTCGGGACGCGTGGGAAGATCTCTGGAGAGA
CCGACAGGGAACTTATACTTTTTTCATGATGGCATCAGTAGAGCAATGTTGAAGGCTCGAAAAGAAATCAAAGAAATGAA
TCAGAAAGGTTACCCAGATGACATGCCTACTGTGCCAACAACCTAG

Domains

Predicted by InterproScan.

DEAD/DEAH box helicase (DEAD)

(98-245)

Helicase conserved C-terminal domain (Helicase_C)

(287-396)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

55.529

96.372

0.535
  comFA/cflA Streptococcus pneumoniae D39

55.529

96.372

0.535
  comFA/cflA Streptococcus pneumoniae R6

55.529

96.372

0.535
  comFA/cflA Streptococcus pneumoniae TIGR4

55.529

96.372

0.535
  comFA/cflA Streptococcus mitis NCTC 12261

54.353

96.372

0.524
  comFA/cflA Streptococcus mitis SK321

53.864

96.825

0.522
  comFA Lactococcus lactis subsp. cremoris KW2

45.476

97.732

0.444
  comFA Latilactobacillus sakei subsp. sakei 23K

40.049

92.29

0.37

Multiple sequence alignment