Detailed information NTG1120440

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: EL084_RS04335
• Genome accession: NZ_LR134292
• Coordinates: 880210..881439 (-)
• Length: 409 a.a.
• NCBI ID: WP_004232044.1
• Uniprot ID: E8JNP3
• Organism: Streptococcus equinus strain NCTC10389
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 875210..886439

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL084_RS04315 (NCTC10389_00912)	-	876434..877102 (+)	669	WP_115255583.1	DUF1275 family protein	-
EL084_RS04320 (NCTC10389_00913)	mmuM	877137..878081 (-)	945	WP_115255232.1	homocysteine S-methyltransferase	-
EL084_RS04325 (NCTC10389_00914)	-	878094..879470 (-)	1377	WP_126440255.1	amino acid permease	-
EL084_RS04330 (NCTC10389_00915)	yihA	879607..880200 (-)	594	WP_126440256.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
EL084_RS04335 (NCTC10389_00916)	clpX	880210..881439 (-)	1230	WP_004232044.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
EL084_RS04345 (NCTC10389_00918)	-	881662..882156 (-)	495	WP_004232047.1	dihydrofolate reductase	-
EL084_RS04350 (NCTC10389_00919)	-	882240..883079 (-)	840	WP_126440257.1	thymidylate synthase	-
EL084_RS04355 (NCTC10389_00920)	-	883411..884589 (+)	1179	WP_126440258.1	hydroxymethylglutaryl-CoA synthase	-
EL084_RS04360 (NCTC10389_00921)	-	884576..885850 (+)	1275	WP_126440259.1	hydroxymethylglutaryl-CoA reductase, degradative	-

Sequence

Protein

• Length: 409 a.a.
• Molecular weight: 45185.67 Da
• Isoelectric Point: 4.4825

>NTDB_id=1120440 EL084_RS04335 WP_004232044.1 880210..881439(-) (clpX) [Streptococcus equinus strain NCTC10389]
MVGNRTNDVKVYCSFCGKSQDEVKKIIAGNNVFICNECVALSQEIIKEELAEEVLADLAEVPKPKELLATLDEYVVGQER
AKRALAVAVYNHYKRVSFADSRDEEDVELQKSNILLIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
LLKLIQAADFNIERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTK
NILFIVGGAFDGIEDIVKQRLGEKIIGFGQNNRKIDEDASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLTADDLVRI
LTEPRNALVKQYQTLLSYDGVELEFDEDALQAIANKAIKRKTGARGLRSIIEETMMDIMFEIPSREEVTKVRITKDAVEG
TDKPILETA

Nucleotide

• Length: 1230 bp

>NTDB_id=1120440 EL084_RS04335 WP_004232044.1 880210..881439(-) (clpX) [Streptococcus equinus strain NCTC10389]
ATGGTTGGAAATCGAACAAATGATGTAAAAGTTTATTGCTCATTTTGTGGAAAAAGCCAAGACGAAGTAAAAAAAATTAT
TGCAGGAAATAATGTCTTTATCTGTAATGAATGTGTGGCTTTATCCCAAGAGATTATTAAAGAAGAGTTAGCAGAAGAAG
TTCTTGCAGATTTGGCAGAAGTTCCAAAACCAAAAGAATTACTAGCTACCCTTGATGAATATGTTGTTGGTCAAGAACGT
GCAAAACGTGCTCTTGCAGTAGCAGTTTACAATCACTACAAGCGTGTATCTTTTGCTGACAGTCGTGATGAAGAAGATGT
TGAATTGCAAAAATCAAACATCTTGCTTATCGGACCAACAGGGTCAGGGAAAACTTTCCTTGCTCAAACATTGGCTAAAA
GTCTTAATGTTCCATTTGCGATTGCAGATGCGACATCATTGACTGAAGCAGGATATGTCGGTGAAGACGTTGAAAATATC
CTTTTGAAACTGATTCAAGCAGCTGATTTTAATATTGAACGTGCTGAACGTGGTATTATATACGTCGATGAAATTGATAA
AATCGCCAAAAAAGGTGAAAATGTTTCAATTACTCGTGACGTTTCAGGTGAAGGTGTTCAACAAGCTCTTCTTAAAATCA
TTGAAGGAACTGTTGCTAGCGTACCACCACAAGGTGGACGTAAACACCCTAACCAAGAAATGATTCAAATTGATACCAAG
AACATTCTTTTCATTGTTGGTGGTGCGTTCGATGGTATCGAAGATATTGTTAAACAACGCCTTGGTGAAAAAATTATTGG
TTTTGGTCAAAATAACCGTAAAATCGATGAAGATGCATCTTATATGCAAGAAATCATCTCAGAAGATATTCAAAAATTTG
GTCTTATTCCAGAGTTTATCGGACGCTTGCCTGTAGTAGCTGCGCTTGAGCAATTGACTGCGGATGATTTGGTTCGTATC
TTGACTGAACCTCGCAATGCCTTGGTTAAACAATACCAAACATTGCTATCTTATGATGGTGTTGAGTTGGAATTTGATGA
AGATGCTCTTCAAGCAATTGCCAATAAAGCTATCAAACGTAAGACAGGTGCGCGTGGACTTCGTTCAATTATCGAAGAAA
CAATGATGGATATCATGTTTGAAATTCCTAGCCGCGAAGAAGTTACCAAAGTTCGCATCACAAAAGATGCTGTCGAAGGT
ACTGATAAACCTATCTTAGAAACTGCATAA

Domains

Predicted by InterproScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (110-305)

• ClpX C4-type zinc finger (zf-C4_ClpX) (12-48)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (312-390)

3D structure

• AlphaFold DB: E8JNP3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	89.731	100	0.897
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.354	98.044	0.572