Detailed information NTG1120261

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: EL087_RS03760
• Genome accession: NZ_LR134288
• Coordinates: 759814..761046 (+)
• Length: 410 a.a.
• NCBI ID: WP_003027977.1
• Uniprot ID: I0SHV1
• Organism: Streptococcus milleri strain NCTC11169
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 754814..766046

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL087_RS03735 (NCTC11169_00741)	-	756480..756746 (+)	267	WP_126406915.1	chorismate mutase	-
EL087_RS03740 (NCTC11169_00742)	-	756761..757972 (+)	1212	WP_126406917.1	voltage-gated chloride channel family protein	-
EL087_RS03745 (NCTC11169_00743)	-	758066..758905 (+)	840	WP_126406919.1	thymidylate synthase	-
EL087_RS03750 (NCTC11169_00744)	-	759090..759602 (+)	513	WP_126406921.1	dihydrofolate reductase	-
EL087_RS03755 (NCTC11169_00745)	-	759603..759776 (+)	174	WP_003024903.1	hypothetical protein	-
EL087_RS03760 (NCTC11169_00746)	clpX	759814..761046 (+)	1233	WP_003027977.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
EL087_RS03765 (NCTC11169_00747)	yihA	761058..761645 (+)	588	WP_126406923.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
EL087_RS03770 (NCTC11169_00748)	-	761768..762475 (+)	708	WP_049512925.1	glucosaminidase domain-containing protein	-
EL087_RS03775 (NCTC11169_00749)	-	762648..764393 (+)	1746	WP_126406925.1	ABC transporter ATP-binding protein	-

Sequence

Protein

• Length: 410 a.a.
• Molecular weight: 45688.21 Da
• Isoelectric Point: 4.4242

>NTDB_id=1120261 EL087_RS03760 WP_003027977.1 759814..761046(+) (clpX) [Streptococcus milleri strain NCTC11169]
MPTNRTNEMMVYCSFCGKSQEEVQKIIAGNNAFICNECVELAQEIIREELAEEVLADLSEVPKPQELLNILNHYVIGQDR
AKRALAVAVYNHYKRINFHDNREDEEDVELQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
ILLKLLQAADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDT
KNILFIVGGAFDGIEEIVKQRLGEKIIGFGQNNKAIDETGSYMQEIISEDIQKFGLIPELIGRLPVFAALEPLTVDDLVR
ILREPKNALVKQYQTLLSYDDVKLEFDDDALQEIANKAIERKTGARGLRSIIEETMMDVMFEVPSQENVKLVRITKEAVD
GTDKPILETA

Nucleotide

• Length: 1233 bp

>NTDB_id=1120261 EL087_RS03760 WP_003027977.1 759814..761046(+) (clpX) [Streptococcus milleri strain NCTC11169]
ATGCCTACAAATCGTACAAACGAAATGATGGTTTATTGTTCTTTTTGTGGTAAAAGCCAAGAAGAAGTGCAAAAGATCAT
CGCAGGAAATAATGCCTTTATTTGTAATGAATGTGTGGAATTAGCACAAGAAATCATCAGAGAGGAACTAGCAGAAGAAG
TGCTAGCAGACTTGTCAGAAGTGCCAAAACCACAAGAATTACTCAATATTTTGAATCACTATGTGATTGGACAAGACCGT
GCTAAGCGTGCTTTGGCTGTGGCTGTCTACAATCACTATAAACGCATCAATTTTCATGATAATCGTGAAGATGAGGAAGA
TGTCGAATTGCAGAAATCCAATATCCTTATGATTGGTCCAACTGGTTCTGGCAAGACCTTCCTCGCTCAAACCTTAGCAA
AAAGTCTGAATGTTCCTTTTGCGATTGCAGATGCGACAGCTTTGACAGAAGCTGGGTATGTCGGAGAAGATGTTGAAAAT
ATTCTCTTGAAACTCTTGCAAGCAGCAGATTTCAATATTGAGCGTGCTGAACGTGGTATCATCTATGTAGATGAGATTGA
CAAAATTGCGAAGAAAAGCGAAAATGTCTCTATTACTCGTGATGTGTCTGGTGAAGGTGTTCAGCAAGCGCTCCTCAAGA
TTATTGAAGGAACTGTAGCCAGCGTACCTCCGCAAGGCGGCCGCAAGCATCCTCAACAAGAGATGATTCAAGTAGATACG
AAAAATATTCTCTTTATCGTTGGTGGTGCATTTGACGGTATTGAAGAAATTGTCAAACAACGTCTAGGCGAAAAAATTAT
CGGTTTTGGTCAAAACAATAAGGCCATTGATGAAACTGGTTCTTATATGCAAGAAATCATCTCTGAAGATATTCAAAAAT
TTGGCTTGATTCCTGAATTGATTGGTCGTTTGCCTGTGTTTGCAGCGCTTGAGCCTTTAACAGTTGATGATTTGGTGCGA
ATCCTTCGCGAACCAAAGAATGCTTTAGTGAAGCAATATCAGACTCTTCTTTCTTATGATGATGTCAAATTGGAGTTTGA
TGATGATGCTCTTCAGGAAATCGCTAACAAGGCCATTGAACGCAAGACAGGTGCGCGTGGATTACGTTCGATTATCGAGG
AAACTATGATGGATGTCATGTTTGAAGTTCCAAGTCAAGAAAATGTGAAGCTGGTACGGATTACTAAGGAAGCAGTTGAC
GGAACGGATAAGCCGATTTTAGAAACAGCATAA

Domains

Predicted by InterProScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (313-390)

• ClpX C4-type zinc finger (zf-C4_ClpX) (12-48)

• AAA domain (Cdc48 subfamily) (AAA_2) (111-306)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	86.829	100	0.868
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.458	98.049	0.573