Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   EL100_RS01205 Genome accession   NZ_LR134285
Coordinates   228499..229797 (-) Length   432 a.a.
NCBI ID   WP_126403862.1    Uniprot ID   -
Organism   Streptococcus australis strain NCTC3168     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 223499..234797
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL100_RS01195 (NCTC3168_00245) hpf 227197..227742 (-) 546 WP_006596830.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  EL100_RS01200 (NCTC3168_00246) - 227831..228436 (-) 606 WP_232011414.1 ComF family protein -
  EL100_RS01205 (NCTC3168_00247) comFA/cflA 228499..229797 (-) 1299 WP_126403862.1 DEAD/DEAH box helicase Machinery gene
  EL100_RS01210 (NCTC3168_00248) - 229853..230485 (+) 633 WP_126403861.1 YigZ family protein -
  EL100_RS01215 (NCTC3168_00249) cysK 230577..231506 (+) 930 WP_126403860.1 cysteine synthase A -
  EL100_RS01220 (NCTC3168_00250) - 231558..231926 (-) 369 WP_126403859.1 S1 RNA-binding domain-containing protein -
  EL100_RS01225 (NCTC3168_00251) - 231923..233329 (-) 1407 WP_126403858.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  EL100_RS01230 (NCTC3168_00252) - 233373..234005 (-) 633 WP_126403857.1 response regulator transcription factor -

Sequence

Protein


Download         Length: 432 a.a.        Molecular weight: 49700.19 Da        Isoelectric Point: 9.4779

>NTDB_id=1120142 EL100_RS01205 WP_126403862.1 228499..229797(-) (comFA/cflA) [Streptococcus australis strain NCTC3168]
MKLEDCYGRLFTQDQLEDDLLEQAQQLPAMVKEKTALICNRCGTQIDKARWKLQIGSYYCRACIQLGRVRSDQALYYFPQ
QAFPQEEVLRWQGTLTPFQSRVSQELVQSLTESKPMMVHAVTGAGKTEMMYQVVAEMIKKGRCVCIATPRIDVCIELYKR
MTLDFSCPISLLHGDSDPYFRTPLVISTTHQLLKFYQAFDLLIIDEVDAFPFVNNPVLYHAVSNAVTKNGKLIYLTATST
EELDKKVKKQEIKRVSLPRRFHGNPLVVPKKVWLKDLRKKIEKKQVPTKLLKLIKEQRKTSFPLILFVSEIELGDKILSL
LRRDFKNEIIELVTSKTDNRLELVEKFRNQEITILVSTTILERGVTFPKVDVFVIEANHRLFTKSALVQIAGRVGRSMER
PTGELLFLAEGTSKEMTQAIKEIKEMNREAGF

Nucleotide


Download         Length: 1299 bp        

>NTDB_id=1120142 EL100_RS01205 WP_126403862.1 228499..229797(-) (comFA/cflA) [Streptococcus australis strain NCTC3168]
ATGAAACTTGAAGATTGTTATGGACGTTTGTTCACCCAAGACCAACTGGAGGATGACCTGCTTGAGCAGGCTCAGCAACT
ACCAGCTATGGTGAAGGAAAAGACGGCGTTGATTTGTAATCGGTGCGGAACCCAGATTGATAAGGCTAGATGGAAACTAC
AGATAGGAAGCTACTATTGTAGAGCATGCATTCAATTAGGAAGAGTTAGAAGCGACCAAGCACTCTACTACTTTCCCCAA
CAAGCCTTTCCGCAAGAAGAAGTCTTAAGATGGCAGGGGACCTTAACGCCCTTTCAGAGTCGGGTTTCCCAGGAGTTGGT
TCAATCCTTAACAGAAAGCAAGCCAATGATGGTACACGCGGTAACAGGAGCAGGTAAAACGGAAATGATGTACCAAGTGG
TGGCGGAAATGATTAAAAAAGGGAGATGTGTGTGCATTGCTACACCAAGGATTGACGTGTGTATTGAATTGTATAAACGG
ATGACGCTGGACTTTTCCTGTCCCATCTCCTTGTTGCACGGTGACTCAGACCCTTATTTCCGAACGCCTCTTGTCATATC
TACTACTCATCAACTACTCAAATTTTATCAAGCTTTCGATCTCCTCATAATCGATGAAGTCGATGCCTTTCCTTTTGTTA
ACAACCCTGTTCTCTATCATGCCGTTTCAAATGCCGTAACCAAAAACGGGAAGCTCATCTATTTGACAGCTACTTCTACA
GAAGAATTGGATAAAAAAGTAAAAAAACAGGAGATAAAACGCGTTAGCTTACCTAGACGCTTTCATGGCAACCCCCTTGT
GGTCCCTAAGAAAGTATGGTTAAAAGATCTACGTAAAAAAATAGAAAAGAAACAAGTGCCAACGAAGTTGCTTAAGCTAA
TAAAAGAACAACGGAAAACCTCCTTCCCCCTAATCCTATTTGTATCAGAAATTGAATTAGGAGACAAAATCCTCAGTCTA
TTAAGAAGGGACTTCAAGAATGAGATCATTGAACTAGTAACCTCAAAAACGGATAATAGGTTGGAACTGGTAGAAAAATT
TCGCAACCAAGAAATTACCATCCTTGTTTCAACGACAATCCTGGAACGAGGAGTCACCTTCCCGAAAGTCGATGTGTTTG
TAATTGAGGCCAATCATCGGCTGTTCACTAAGAGCGCCCTGGTCCAAATTGCTGGTCGTGTGGGAAGAAGTATGGAAAGA
CCCACAGGCGAATTGCTTTTTCTAGCAGAAGGAACCAGCAAAGAAATGACACAAGCCATTAAAGAAATAAAAGAAATGAA
TCGGGAGGCAGGGTTTTGA

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(288-396)

Type III restriction enzyme, res subunit (ResIII)

(95-238)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus mitis NCTC 12261

61.432

100

0.616
  comFA/cflA Streptococcus mitis SK321

60.97

100

0.611
  comFA/cflA Streptococcus pneumoniae D39

61.449

99.074

0.609
  comFA/cflA Streptococcus pneumoniae R6

61.449

99.074

0.609
  comFA/cflA Streptococcus pneumoniae TIGR4

61.449

99.074

0.609
  comFA/cflA Streptococcus pneumoniae Rx1

61.449

99.074

0.609
  comFA Lactococcus lactis subsp. cremoris KW2

53.299

91.204

0.486
  comFA Latilactobacillus sakei subsp. sakei 23K

37.963

100

0.38

Multiple sequence alignment