Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   EL100_RS00850 Genome accession   NZ_LR134285
Coordinates   164629..166896 (+) Length   755 a.a.
NCBI ID   WP_126403910.1    Uniprot ID   -
Organism   Streptococcus australis strain NCTC3168     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 159629..171896
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL100_RS00820 (NCTC3168_00168) - 159644..160531 (-) 888 WP_126403914.1 polyprenyl synthetase family protein -
  EL100_RS00825 (NCTC3168_00169) - 160528..160740 (-) 213 WP_006596769.1 exodeoxyribonuclease VII small subunit -
  EL100_RS00830 (NCTC3168_00170) xseA 160718..162058 (-) 1341 WP_126403913.1 exodeoxyribonuclease VII large subunit -
  EL100_RS00835 (NCTC3168_00171) - 162171..163025 (-) 855 WP_126403912.1 NAD(P)H-hydrate dehydratase -
  EL100_RS00840 (NCTC3168_00172) - 163158..164012 (-) 855 WP_164555429.1 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase -
  EL100_RS00845 (NCTC3168_00173) - 164169..164399 (-) 231 WP_006596773.1 DUF1797 family protein -
  EL100_RS00850 (NCTC3168_00174) clpE 164629..166896 (+) 2268 WP_126403910.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  EL100_RS00855 (NCTC3168_00175) - 167156..167605 (+) 450 WP_126403909.1 NUDIX hydrolase -
  EL100_RS00860 (NCTC3168_00176) - 167673..167975 (+) 303 WP_006596776.1 DUF1827 family protein -
  EL100_RS00865 (NCTC3168_00177) - 168056..168490 (-) 435 WP_126403908.1 GNAT family N-acetyltransferase -
  EL100_RS00870 (NCTC3168_00178) ileS 168551..171343 (-) 2793 WP_126403907.1 isoleucine--tRNA ligase -

Sequence

Protein


Download         Length: 755 a.a.        Molecular weight: 83818.85 Da        Isoelectric Point: 5.0597

>NTDB_id=1120139 EL100_RS00850 WP_126403910.1 164629..166896(+) (clpE) [Streptococcus australis strain NCTC3168]
MLCQNCKINDSTIHLYTNVNGHQQQVDLCQNCYQIMKTDPNNSLLAGLNQQNRGGRDPFEDFFNQLGNFQAPQEPQTPPT
QSGGGYGGGNGYGSNGNGRSSGPNRAQAKQQPKGLLEEFGINVTEIARRGDIDPVIGRDEEILRVIEILNRRTKNNPVLI
GEPGVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQQLMEEIRRREDVILFIDEIHEIVGA
GSAGDGNMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPTVEETITILKGIQKKYEDYHHVHYT
DSAIEAAALLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKAQATRDEDFEKAAYFRDQIAKY
KEMQGQQVTDQDTPVISEKTIEHIVEQKTNIPVGDLKEKEQSQLINLAADLKAHVIGQDEAVEKIAKAIRRNRVGLGTPN
RPIGSFLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEKVRRNPYSLIL
LDEVEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKAEANVGFGAAREGRTNSILGELGNFFSPEFM
NRFDGIIEFKSLSKENLLQIVTLMLDDVNQRLAHNDIHLDVTDKVKEKLVDLGYDPKMGARPLRRTIQDYIEDAITDYYL
ENPSEKDLKAVMTSNGKICIKGKNKPANEAEKGTE

Nucleotide


Download         Length: 2268 bp        

>NTDB_id=1120139 EL100_RS00850 WP_126403910.1 164629..166896(+) (clpE) [Streptococcus australis strain NCTC3168]
ATGCTTTGTCAAAACTGTAAAATCAACGATTCAACCATTCATCTTTATACAAATGTGAATGGTCACCAACAACAAGTAGA
CCTTTGCCAGAACTGCTATCAAATTATGAAAACCGATCCTAACAATAGTCTCCTGGCAGGATTAAACCAACAAAATCGCG
GAGGGCGGGATCCTTTTGAAGATTTCTTCAATCAACTGGGCAACTTCCAAGCCCCCCAAGAACCTCAAACGCCACCAACT
CAATCTGGAGGGGGCTATGGTGGCGGAAATGGCTACGGTTCAAATGGGAACGGTCGTTCTTCAGGACCGAATAGAGCCCA
AGCCAAACAACAACCAAAAGGCCTCTTAGAAGAGTTCGGAATCAATGTCACAGAAATTGCTCGTCGTGGCGATATCGATC
CGGTCATTGGTCGTGATGAAGAGATTCTCCGTGTCATCGAAATTCTCAACCGTCGTACCAAAAACAACCCTGTCTTGATC
GGTGAACCGGGTGTCGGGAAAACTGCTGTCGTAGAAGGGCTAGCTCAAAAGATTGTCGATGGGGATGTCCCTCATAAATT
GCAAGGCAAGCAAGTTATTCGCTTAGACGTTGTTAGTCTTGTTCAAGGAACTGGGATCCGAGGCCAATTTGAAGAGCGCA
TGCAACAATTAATGGAGGAAATCCGTCGCCGTGAAGATGTGATTTTATTCATCGACGAAATTCATGAAATCGTCGGTGCT
GGATCTGCTGGAGACGGCAACATGGATGCTGGAAATATCCTCAAACCAGCCCTCGCTCGTGGCGAATTGCAATTAGTCGG
TGCGACAACACTTAATGAATACCGGATTATCGAGAAGGATGCGGCACTTGAACGCCGGATGCAACCCGTTAAGGTCGATG
AGCCAACGGTTGAAGAAACTATCACCATCCTCAAAGGGATTCAAAAGAAATATGAGGACTACCACCACGTCCACTACACA
GATAGTGCCATCGAAGCTGCAGCACTCCTCTCCAATCGCTATATCCAAGACCGCTTCTTGCCCGACAAGGCCATTGACCT
CTTGGATGAAGCTGGCTCTAAGATGAATTTAACCCTCAATTTCGTCGATCCAAAGGTCATTGACCAACGCTTAATTGAAG
CTGAAAATCTCAAGGCCCAAGCGACGCGTGATGAAGATTTCGAAAAAGCTGCCTACTTCCGTGACCAAATCGCTAAGTAC
AAAGAAATGCAAGGGCAACAGGTCACTGATCAAGATACGCCAGTTATTAGCGAAAAGACCATCGAACACATCGTCGAACA
AAAGACCAATATTCCAGTTGGAGATTTGAAAGAAAAAGAACAATCCCAATTGATCAATTTGGCAGCTGATTTGAAGGCTC
ATGTCATCGGCCAAGATGAGGCTGTTGAAAAAATTGCTAAGGCTATCCGTCGTAATCGGGTAGGACTTGGAACGCCCAAC
CGTCCAATCGGTAGCTTCCTCTTTGTTGGACCGACTGGCGTCGGGAAGACAGAGTTGTCCAAACAATTGGCTATCGAACT
CTTCGGTTCTGCTGACAGTATGATTCGTTTTGATATGAGCGAATACATGGAGAAGCATGCCGTTGCTAAACTGGTCGGCG
CCCCTCCAGGATATGTTGGTTACGAAGAAGCTGGCCAGCTGACTGAAAAAGTACGTCGCAACCCCTACTCTCTCATTCTC
TTGGATGAGGTAGAAAAGGCCCATCCTGATGTCATGCATATGTTCCTCCAAGTCTTGGATGATGGTCGCTTGACAGATGG
TCAAGGACGAACAGTGAGCTTCAAAGATACCATCATCATCATGACTTCTAATGCGGGAACTGGAAAAGCGGAGGCTAACG
TTGGTTTTGGGGCAGCTCGTGAAGGACGTACCAATTCTATCCTCGGTGAACTTGGAAACTTCTTTAGTCCAGAATTCATG
AACCGGTTTGATGGTATTATTGAATTTAAATCCTTGTCTAAAGAAAACCTCCTTCAAATCGTCACTCTTATGCTCGATGA
TGTCAATCAACGCCTGGCCCACAATGATATCCACCTCGATGTTACCGATAAGGTCAAGGAAAAATTGGTTGATTTGGGCT
ACGATCCAAAAATGGGAGCTCGTCCACTTCGTCGTACCATTCAGGACTATATCGAAGATGCCATTACAGATTACTACTTA
GAAAATCCTAGTGAAAAAGATCTGAAGGCTGTCATGACCAGCAATGGAAAGATTTGCATTAAAGGAAAGAACAAACCTGC
TAACGAGGCAGAAAAAGGAACTGAATAA

Domains

Predicted by InterproScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(652-726)

AAA domain (Cdc48 subfamily) (AAA_2)

(481-644)

ATPase family associated with various cellular activities (AAA) (AAA)

(158-277)

AAA lid domain (AAA_lid_9)

(296-393)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus pneumoniae Rx1

87.169

100

0.873
  clpE Streptococcus pneumoniae D39

87.169

100

0.873
  clpE Streptococcus pneumoniae R6

87.169

100

0.873
  clpE Streptococcus pneumoniae TIGR4

87.169

100

0.873
  clpE Streptococcus mutans UA159

85.18

99.205

0.845
  clpC Lactococcus lactis subsp. cremoris KW2

76.058

100

0.762
  clpC Bacillus subtilis subsp. subtilis str. 168

50.954

90.199

0.46
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

48.804

83.046

0.405
  clpC Streptococcus pneumoniae Rx1

47.792

83.974

0.401
  clpC Streptococcus pneumoniae D39

47.792

83.974

0.401
  clpC Streptococcus pneumoniae TIGR4

47.634

83.974

0.4
  clpC Streptococcus thermophilus LMD-9

47.377

83.311

0.395
  clpC Streptococcus thermophilus LMG 18311

47.209

83.046

0.392
  clpC Streptococcus mutans UA159

47.504

82.252

0.391

Multiple sequence alignment