Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   LOA_RS07445 Genome accession   NZ_CP004006
Coordinates   1518156..1519373 (+) Length   405 a.a.
NCBI ID   WP_025385786.1    Uniprot ID   W0BBH1
Organism   Legionella oakridgensis ATCC 33761 = DSM 21215     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1513156..1524373
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LOA_RS07420 (Loa_01658) - 1513694..1514395 (+) 702 WP_025385781.1 L,D-transpeptidase family protein -
  LOA_RS07425 (Loa_01659) - 1514407..1514967 (-) 561 WP_025385782.1 hypoxanthine-guanine phosphoribosyltransferase -
  LOA_RS07430 (Loa_01660) - 1514994..1515320 (-) 327 WP_025385783.1 DUF1820 family protein -
  LOA_RS07435 (Loa_01661) - 1515419..1516180 (-) 762 WP_025385784.1 methyltransferase domain-containing protein -
  LOA_RS07440 (Loa_01662) pilB 1516430..1518151 (+) 1722 WP_025385785.1 type IV-A pilus assembly ATPase PilB Machinery gene
  LOA_RS07445 (Loa_01663) pilC 1518156..1519373 (+) 1218 WP_025385786.1 type II secretion system F family protein Machinery gene
  LOA_RS07450 (Loa_01664) - 1519377..1520264 (+) 888 WP_025385787.1 prepilin peptidase -
  LOA_RS07455 (Loa_01665) - 1520253..1523963 (-) 3711 WP_147370113.1 hypothetical protein -

Sequence

Protein


Download         Length: 405 a.a.        Molecular weight: 44665.53 Da        Isoelectric Point: 9.4238

>NTDB_id=112003 LOA_RS07445 WP_025385786.1 1518156..1519373(+) (pilC) [Legionella oakridgensis ATCC 33761 = DSM 21215]
MAKNTNTTVTYQWEGVNQSGEKLNGVIDARSIAIAKTELRKQGVITRKIVKKRAPFFKKSKKIKPIDITVFSRQMATMIE
AGIPLIQSFEIVAKGQSNQRMKDLIETIKKDVESGLTLAESLKKHPAFFNELFCNLVDAGEKSGSLDVMLDKIATYKEKI
ETIKKKIKKALTYPMAVIVVAFLVTAGLLIFVVPQFESLFEGFGADLPALTRGVISLSEFFQSYWYIIFGLLGLGVYSFI
YARNHSAHFAHQVDRYLLKIPVVGTILEKAAIARFSRTLSITFAAGLPLVEALKSVSGATGNILYAEATDKIREEVSNGQ
QMQIAMENTKLFPNMVVQMIAIGEESGALEQMLTKVADFFEEEVDNAVDSLSSLLEPMIMAILGILVGGLVVAMYLPIFK
LGSVV

Nucleotide


Download         Length: 1218 bp        

>NTDB_id=112003 LOA_RS07445 WP_025385786.1 1518156..1519373(+) (pilC) [Legionella oakridgensis ATCC 33761 = DSM 21215]
ATGGCTAAAAACACAAACACCACCGTCACTTATCAGTGGGAAGGAGTGAATCAATCCGGAGAAAAACTCAATGGTGTTAT
TGATGCTCGCAGTATTGCTATCGCTAAAACAGAGTTGCGCAAACAGGGAGTTATCACTCGCAAAATCGTTAAAAAAAGAG
CACCTTTCTTTAAAAAAAGCAAAAAAATAAAACCAATTGACATCACCGTATTTAGTCGCCAAATGGCAACCATGATTGAA
GCCGGTATTCCTTTAATTCAATCGTTTGAAATCGTTGCCAAGGGCCAAAGCAATCAGCGTATGAAAGATTTGATTGAGAC
CATCAAAAAAGATGTAGAATCCGGCTTAACACTAGCAGAATCCCTTAAAAAACATCCTGCTTTTTTCAACGAACTGTTTT
GTAACCTGGTGGATGCTGGCGAAAAATCAGGCTCTTTAGATGTTATGCTTGATAAGATAGCCACTTATAAGGAAAAAATA
GAAACCATTAAAAAGAAAATAAAAAAAGCACTTACCTATCCTATGGCCGTTATTGTGGTAGCATTTCTCGTTACCGCTGG
ATTGTTAATCTTTGTTGTCCCGCAATTTGAATCTTTATTTGAAGGGTTTGGAGCCGATCTTCCAGCATTAACCCGTGGTG
TCATCAGCCTCTCGGAATTCTTCCAATCCTATTGGTATATTATATTTGGTTTGTTAGGTCTTGGGGTGTATAGCTTTATC
TATGCTCGCAATCATTCAGCGCATTTTGCCCACCAAGTAGACCGCTATTTATTAAAAATTCCAGTGGTTGGCACCATTCT
TGAAAAAGCGGCCATAGCCCGTTTTTCACGTACCCTTTCCATTACTTTTGCGGCCGGTTTACCCTTAGTGGAAGCCTTGA
AATCCGTATCAGGCGCAACAGGAAATATTTTATATGCTGAAGCAACGGATAAAATCAGGGAAGAAGTATCCAATGGGCAA
CAAATGCAAATCGCCATGGAAAATACGAAATTATTTCCTAATATGGTGGTACAAATGATAGCTATTGGTGAAGAATCTGG
TGCATTGGAACAAATGCTTACTAAGGTGGCTGATTTTTTTGAAGAAGAAGTTGATAATGCCGTAGACTCATTAAGTAGTT
TATTAGAGCCAATGATCATGGCAATATTAGGTATATTGGTAGGCGGCCTGGTGGTCGCCATGTATTTACCCATCTTTAAA
CTTGGCTCTGTGGTATAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(71-194)

Type II secretion system (T2SS), protein F (T2SSF)

(275-397)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB W0BBH1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Legionella pneumophila strain ERS1305867

77.094

100

0.773
  pilC Pseudomonas stutzeri DSM 10701

54.433

100

0.546
  pilC Acinetobacter baylyi ADP1

53.941

100

0.541
  pilC Acinetobacter baumannii D1279779

52.346

100

0.523
  pilG Neisseria meningitidis 44/76-A

44.903

100

0.457
  pilG Neisseria gonorrhoeae MS11

44.66

100

0.454
  pilC Vibrio campbellii strain DS40M4

40.5

98.765

0.4
  pilC Vibrio cholerae strain A1552

40.909

97.778

0.4
  pilC Thermus thermophilus HB27

35.337

100

0.363

Multiple sequence alignment