Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   EL079_RS03670 Genome accession   NZ_LR134283
Coordinates   741048..742280 (-) Length   410 a.a.
NCBI ID   WP_003027977.1    Uniprot ID   I0SHV1
Organism   Streptococcus anginosus strain NCTC10713     
Function   require for competence development (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 733302..744030 741048..742280 within 0


Gene organization within MGE regions


Location: 733302..744030
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL079_RS03640 (NCTC10713_00769) - 733302..734042 (+) 741 WP_003032251.1 amino acid ABC transporter ATP-binding protein -
  EL079_RS03645 (NCTC10713_00770) - 734418..735953 (+) 1536 WP_003032268.1 ATP-binding cassette domain-containing protein -
  EL079_RS03650 (NCTC10713_00771) - 735974..737722 (-) 1749 WP_003032246.1 ABC transporter ATP-binding protein -
  EL079_RS03655 (NCTC10713_00772) - 737703..739448 (-) 1746 WP_003032265.1 ABC transporter ATP-binding protein -
  EL079_RS03660 (NCTC10713_00773) - 739621..740328 (-) 708 WP_003032270.1 glucosaminidase domain-containing protein -
  EL079_RS03665 (NCTC10713_00774) yihA 740449..741036 (-) 588 WP_003032247.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  EL079_RS03670 (NCTC10713_00775) clpX 741048..742280 (-) 1233 WP_003027977.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  EL079_RS03675 (NCTC10713_00776) - 742319..742492 (-) 174 WP_003032252.1 hypothetical protein -
  EL079_RS03680 (NCTC10713_00777) - 742492..743004 (-) 513 WP_003032260.1 dihydrofolate reductase -
  EL079_RS03685 (NCTC10713_00778) - 743191..744030 (-) 840 WP_003032264.1 thymidylate synthase -

Sequence

Protein


Download         Length: 410 a.a.        Molecular weight: 45688.21 Da        Isoelectric Point: 4.4242

>NTDB_id=1120016 EL079_RS03670 WP_003027977.1 741048..742280(-) (clpX) [Streptococcus anginosus strain NCTC10713]
MPTNRTNEMMVYCSFCGKSQEEVQKIIAGNNAFICNECVELAQEIIREELAEEVLADLSEVPKPQELLNILNHYVIGQDR
AKRALAVAVYNHYKRINFHDNREDEEDVELQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
ILLKLLQAADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDT
KNILFIVGGAFDGIEEIVKQRLGEKIIGFGQNNKAIDETGSYMQEIISEDIQKFGLIPELIGRLPVFAALEPLTVDDLVR
ILREPKNALVKQYQTLLSYDDVKLEFDDDALQEIANKAIERKTGARGLRSIIEETMMDVMFEVPSQENVKLVRITKEAVD
GTDKPILETA

Nucleotide


Download         Length: 1233 bp        

>NTDB_id=1120016 EL079_RS03670 WP_003027977.1 741048..742280(-) (clpX) [Streptococcus anginosus strain NCTC10713]
ATGCCTACAAATCGTACGAACGAAATGATGGTTTATTGTTCTTTTTGTGGTAAAAGCCAAGAGGAAGTTCAAAAAATTAT
CGCAGGAAATAATGCCTTCATTTGTAATGAATGTGTGGAATTAGCACAAGAAATTATTAGAGAAGAATTGGCAGAAGAAG
TGCTGGCAGACTTGTCAGAAGTACCAAAACCGCAAGAACTACTCAATATTTTGAATCATTATGTGATTGGACAAGACCGT
GCTAAGCGAGCATTGGCCGTTGCTGTTTACAATCACTATAAACGCATCAATTTTCATGATAATCGTGAAGATGAGGAAGA
TGTCGAATTGCAGAAATCCAATATCCTCATGATTGGGCCAACTGGTTCTGGCAAGACCTTTCTCGCTCAAACTTTGGCAA
AAAGTCTGAATGTTCCTTTTGCGATTGCAGATGCGACAGCTTTGACAGAAGCTGGGTATGTCGGAGAAGATGTTGAAAAT
ATTCTCTTGAAACTCTTGCAAGCAGCAGATTTCAATATTGAGCGTGCTGAACGTGGTATCATCTATGTAGATGAGATTGA
TAAAATTGCGAAGAAAAGCGAAAATGTCTCTATTACTCGTGATGTGTCTGGTGAAGGTGTTCAGCAAGCGCTCCTCAAAA
TTATTGAAGGAACAGTAGCCAGCGTACCTCCGCAAGGCGGCCGCAAGCACCCTCAACAAGAGATGATTCAAGTAGATACG
AAAAATATTCTCTTTATCGTTGGTGGTGCATTTGACGGTATTGAAGAAATTGTCAAACAACGTCTAGGCGAAAAAATTAT
CGGTTTTGGTCAAAACAACAAGGCCATTGATGAAACTGGTTCTTATATGCAAGAAATCATCTCTGAAGATATTCAAAAAT
TTGGCTTGATTCCGGAATTGATTGGTCGTTTGCCTGTGTTTGCAGCGCTTGAGCCTTTAACAGTTGATGATTTGGTGCGA
ATCCTTCGCGAACCAAAGAATGCTTTAGTGAAGCAATATCAGACTCTTCTTTCTTATGATGATGTCAAATTGGAGTTTGA
TGATGATGCTCTCCAAGAGATTGCCAACAAAGCCATTGAACGTAAGACAGGTGCGCGTGGATTGCGGTCGATTATCGAGG
AAACTATGATGGATGTCATGTTTGAAGTTCCAAGTCAAGAAAATGTGAAGTTAGTGCGGATTACCAAGGAAGCAGTTGAC
GGAACGGATAAGCCGATTTTAGAAACAGCATAA

Domains

Predicted by InterproScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(313-390)

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)

AAA domain (Cdc48 subfamily) (AAA_2)

(111-306)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I0SHV1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

86.829

100

0.868
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.458

98.049

0.573

Multiple sequence alignment