Detailed information NTG1119907

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: EL076_RS08125
• Genome accession: NZ_LR134275
• Coordinates: 1611579..1612655 (-)
• Length: 358 a.a.
• NCBI ID: WP_197716138.1
• Uniprot ID: A0A448ACF9
• Organism: Streptococcus vestibularis strain NCTC12167
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1606579..1617655

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL076_RS10360 (NCTC12167_01593)	-	1607320..1607481 (+)	162	WP_082162585.1	MFS transporter	-
EL076_RS10365	-	1607501..1607641 (+)	141	WP_164555383.1	hypothetical protein	-
EL076_RS08105 (NCTC12167_01594)	-	1607690..1609756 (-)	2067	WP_126429976.1	sodium:proton antiporter	-
EL076_RS08110 (NCTC12167_01595)	-	1609765..1610007 (-)	243	WP_003094091.1	hypothetical protein	-
EL076_RS08115 (NCTC12167_01596)	-	1610004..1610552 (-)	549	WP_048788174.1	class I SAM-dependent methyltransferase	-
EL076_RS08120 (NCTC12167_01597)	-	1610549..1611493 (-)	945	WP_003094636.1	TIGR01212 family radical SAM protein	-
EL076_RS08125 (NCTC12167_01598)	sepM	1611579..1612655 (-)	1077	WP_197716138.1	SepM family pheromone-processing serine protease	Regulator
EL076_RS08130 (NCTC12167_01599)	coaD	1612633..1613130 (-)	498	WP_126429978.1	pantetheine-phosphate adenylyltransferase	-
EL076_RS08135 (NCTC12167_01600)	rsmD	1613163..1613702 (-)	540	WP_003093460.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
EL076_RS08140 (NCTC12167_01601)	-	1613885..1615159 (-)	1275	WP_126429980.1	2-hydroxycarboxylate transporter family protein	-
EL076_RS08145 (NCTC12167_01602)	-	1615181..1616803 (-)	1623	WP_003096209.1	malolactic enzyme	-

Sequence

Protein

• Length: 358 a.a.
• Molecular weight: 39291.23 Da
• Isoelectric Point: 9.6574

>NTDB_id=1119907 EL076_RS08125 WP_197716138.1 1611579..1612655(-) (sepM) [Streptococcus vestibularis strain NCTC12167]
MANKTKSKLLLEKMWRIKWWLLSIFTVLFLLFALFFPLNNYYVELPGGAFDTKEVLTVDKKADDSKGSYNFVAVAQTKAT
LALMLYAQLNDFAKLQTAKEATGNYSDEDFMRINQFYMETSQNQAIYQGLTLAGKEASLEYMGVYVLQVADDSSFKSVLN
IADTVTAVNGKTFDNSTDLIKYVQGLKLGSKVKVTYTTDDKEKTATGKIIKIANGKNGIGIGLTDHTEVKSPENVKFKLD
GVGGPSAGLMFTLAIYDQVSGQDLKAGRKIAGTGTIEKDGSVGDIGGAYLKVKSAADSGADIFFVPNNPVTKEMKKVDPD
AKTNYQEAKEAAKKLRTKMKIVPIKTAQEAIDYLKKTK

Nucleotide

• Length: 1077 bp

>NTDB_id=1119907 EL076_RS08125 WP_197716138.1 1611579..1612655(-) (sepM) [Streptococcus vestibularis strain NCTC12167]
GTGGCAAACAAGACAAAATCTAAATTACTATTAGAGAAAATGTGGCGTATTAAGTGGTGGTTATTAAGTATTTTTACGGT
ACTTTTCCTCCTTTTTGCCCTCTTTTTCCCGCTAAATAATTATTATGTTGAGCTTCCGGGTGGTGCTTTTGATACCAAGG
AAGTCTTGACTGTAGATAAGAAAGCTGATGATTCAAAAGGATCCTACAATTTTGTGGCGGTGGCCCAAACCAAGGCGACT
TTGGCCTTGATGCTCTATGCTCAGCTTAATGATTTTGCAAAGCTTCAAACAGCTAAAGAAGCAACCGGAAATTACTCTGA
TGAAGATTTCATGCGTATTAACCAATTTTACATGGAGACTTCTCAAAACCAAGCGATTTATCAGGGCTTGACACTGGCTG
GTAAGGAGGCTAGTTTGGAGTATATGGGTGTCTATGTGCTTCAGGTTGCTGATGATTCTAGCTTCAAGAGTGTCCTCAAT
ATCGCTGATACGGTGACGGCTGTTAATGGCAAGACCTTTGATAATTCTACTGACTTGATTAAATACGTTCAAGGGCTTAA
GTTGGGTTCAAAAGTCAAGGTCACTTATACGACAGATGACAAAGAAAAGACTGCTACTGGTAAGATTATTAAGATCGCCA
ATGGCAAAAATGGTATTGGTATCGGCCTAACGGACCATACTGAGGTCAAGAGTCCTGAGAATGTTAAGTTTAAACTAGAT
GGTGTTGGCGGACCGAGCGCTGGTCTTATGTTTACCTTAGCTATTTACGATCAGGTGTCTGGTCAAGATCTTAAGGCTGG
TCGTAAGATTGCTGGGACAGGAACTATTGAAAAAGATGGTTCGGTTGGTGATATCGGTGGTGCCTACCTTAAGGTGAAAT
CAGCGGCTGATAGTGGCGCAGACATTTTCTTCGTGCCAAATAATCCAGTAACTAAGGAAATGAAAAAGGTTGATCCGGAT
GCCAAGACTAATTATCAAGAGGCCAAGGAAGCTGCCAAGAAACTGAGGACCAAGATGAAAATCGTCCCTATTAAAACAGC
TCAAGAAGCCATTGATTATTTGAAAAAAACTAAATAA

Domains

Predicted by InterproScan.

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (244-321)

• PDZ domain (PDZ_2) (142-206)

3D structure

• AlphaFold DB: A0A448ACF9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	64.809	95.251	0.617