Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   EL076_RS01960 Genome accession   NZ_LR134275
Coordinates   360621..361940 (+) Length   439 a.a.
NCBI ID   WP_126429039.1    Uniprot ID   -
Organism   Streptococcus vestibularis strain NCTC12167     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 355621..366940
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL076_RS01935 (NCTC12167_00387) - 356479..357243 (+) 765 WP_003093115.1 ABC transporter ATP-binding protein -
  EL076_RS01940 (NCTC12167_00388) - 357243..357953 (+) 711 WP_126429037.1 ABC transporter ATP-binding protein -
  EL076_RS01945 (NCTC12167_00389) - 358088..358747 (+) 660 WP_003093134.1 CBS and ACT domain-containing protein -
  EL076_RS01950 (NCTC12167_00390) cysK 358912..359838 (-) 927 WP_003093123.1 cysteine synthase A -
  EL076_RS01955 (NCTC12167_00391) - 359940..360566 (-) 627 WP_003093151.1 YigZ family protein -
  EL076_RS01960 (NCTC12167_00392) comFA/cflA 360621..361940 (+) 1320 WP_126429039.1 DEAD/DEAH box helicase Machinery gene
  EL076_RS01965 (NCTC12167_00393) - 361921..362583 (+) 663 WP_003093132.1 ComF family protein -
  EL076_RS01970 (NCTC12167_00394) hpf 362661..363209 (+) 549 WP_003093130.1 ribosome hibernation-promoting factor, HPF/YfiA family -

Sequence

Protein


Download         Length: 439 a.a.        Molecular weight: 50500.72 Da        Isoelectric Point: 9.8199

>NTDB_id=1119875 EL076_RS01960 WP_126429039.1 360621..361940(+) (comFA/cflA) [Streptococcus vestibularis strain NCTC12167]
MIPKEYYGRLFTKAQLPVDYLSEAVKLESMIKVDKKLRCKRCYSQIEEDWQLPNGQYYCRACIVFGRNQEGKELYYFPSE
KSEVDFPVLKWLGKLTPYQNEVSEKLLKTYKNQKHSLVHAVTGAGKTEMIYKIVAYVLENKNRVAIASPRVDVCRELFLR
MQKDFTCSISLLHADSEPYDGSPLVIATTHQLLKFYHSFDLIIVDEVDAFPFVGNVMLNHAVKQAKTETGRYIYLTATST
LALEEQVRLGALEKHHLARRFHGNPLVLPRFFWQGRLQKSLTNGKLPSLLIHQIKKQRKSNFPLLIFFPNIAVGEKFSIT
LKKYLPTENISFVSSKSEERSTIVEKFRKKELSILVTTTILERGVTFPQVDVFVCMANHHLYTSSSLIQIGGRVGRSPER
PTGKLYFFHEGLSKSMLQCRKEINAMNKKGGFENEVSTM

Nucleotide


Download         Length: 1320 bp        

>NTDB_id=1119875 EL076_RS01960 WP_126429039.1 360621..361940(+) (comFA/cflA) [Streptococcus vestibularis strain NCTC12167]
ATGATACCTAAAGAATATTATGGACGACTATTTACGAAAGCACAGTTACCAGTGGACTATCTCTCAGAGGCTGTAAAATT
AGAAAGTATGATAAAGGTTGATAAAAAACTTAGATGTAAAAGATGTTATAGTCAAATAGAGGAAGATTGGCAATTACCGA
ATGGTCAGTATTATTGTAGAGCGTGTATTGTCTTTGGTCGAAACCAAGAAGGTAAAGAACTCTATTACTTTCCTTCAGAA
AAATCAGAAGTAGATTTTCCTGTCTTGAAATGGTTAGGAAAACTGACTCCTTATCAAAATGAGGTCTCGGAAAAGCTATT
AAAGACTTATAAAAATCAAAAACACAGTCTTGTTCATGCAGTGACTGGTGCTGGTAAGACAGAGATGATTTATAAGATTG
TTGCCTATGTTCTTGAAAATAAAAATCGTGTCGCCATTGCAAGTCCCCGAGTTGATGTTTGTCGAGAATTGTTTCTACGT
ATGCAGAAAGATTTTACTTGTAGTATTTCTCTGCTTCATGCTGATAGTGAACCATATGATGGTAGTCCGCTCGTTATAGC
TACCACTCATCAATTACTAAAATTTTATCATAGCTTTGACTTGATTATTGTTGACGAAGTTGATGCCTTCCCCTTTGTAG
GGAATGTCATGTTAAATCATGCTGTTAAACAAGCAAAGACGGAAACAGGTCGATATATTTACTTAACAGCAACTTCTACA
TTAGCTTTAGAGGAGCAAGTTCGCCTTGGAGCTTTAGAAAAGCATCACCTTGCCAGACGCTTCCATGGAAATCCTTTAGT
CCTTCCTCGTTTCTTTTGGCAAGGAAGGTTACAAAAGTCGTTGACGAACGGCAAGCTCCCAAGCCTTCTAATTCACCAGA
TTAAGAAGCAGCGTAAATCAAATTTTCCTCTATTAATCTTTTTTCCCAATATAGCAGTAGGTGAAAAGTTTAGTATTACC
CTAAAAAAATACCTCCCTACTGAAAACATATCCTTTGTTTCATCAAAAAGCGAGGAGCGTTCAACCATCGTAGAGAAATT
CCGAAAAAAAGAACTGTCAATCTTAGTGACAACAACTATTCTCGAACGTGGTGTTACCTTTCCACAAGTAGATGTTTTTG
TTTGTATGGCAAATCATCACTTATATACTAGTTCGAGTCTTATTCAGATTGGTGGTAGGGTGGGGCGTTCGCCCGAGAGA
CCTACAGGGAAACTCTATTTCTTTCATGAAGGATTATCTAAATCAATGTTGCAATGTCGGAAAGAAATAAATGCAATGAA
TAAAAAAGGAGGCTTTGAAAATGAAGTGTCTACTATGTAA

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(290-396)

Type III restriction enzyme, res subunit (ResIII)

(94-205)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

55.684

98.178

0.547
  comFA/cflA Streptococcus pneumoniae D39

55.684

98.178

0.547
  comFA/cflA Streptococcus pneumoniae R6

55.684

98.178

0.547
  comFA/cflA Streptococcus pneumoniae TIGR4

55.684

98.178

0.547
  comFA/cflA Streptococcus mitis NCTC 12261

55.349

97.95

0.542
  comFA/cflA Streptococcus mitis SK321

54.419

97.95

0.533
  comFA Lactococcus lactis subsp. cremoris KW2

45.714

95.672

0.437
  comFA Latilactobacillus sakei subsp. sakei 23K

37.241

99.089

0.369

Multiple sequence alignment