Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   EL086_RS03080 Genome accession   NZ_LR134274
Coordinates   619648..620874 (+) Length   408 a.a.
NCBI ID   WP_002890340.1    Uniprot ID   J7SIE0
Organism   Streptococcus salivarius strain NCTC8618     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 614648..625874
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL086_RS03055 (NCTC8618_03032) - 615074..616345 (-) 1272 WP_013990948.1 hydroxymethylglutaryl-CoA reductase, degradative -
  EL086_RS03060 (NCTC8618_03033) - 616347..617513 (-) 1167 WP_038675548.1 hydroxymethylglutaryl-CoA synthase -
  EL086_RS03065 (NCTC8618_03034) - 617984..618844 (+) 861 WP_002886020.1 thymidylate synthase -
  EL086_RS03070 (NCTC8618_03035) - 618952..619455 (+) 504 WP_038675550.1 dihydrofolate reductase -
  EL086_RS03075 (NCTC8618_03036) - 619460..619630 (+) 171 WP_002886174.1 hypothetical protein -
  EL086_RS03080 (NCTC8618_03037) clpX 619648..620874 (+) 1227 WP_002890340.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  EL086_RS03085 (NCTC8618_03038) yihA 620884..621483 (+) 600 WP_038675553.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  EL086_RS03090 (NCTC8618_03039) - 621613..622989 (+) 1377 WP_038675555.1 amino acid permease -
  EL086_RS03095 (NCTC8618_03040) mmuM 623002..623952 (+) 951 WP_038675557.1 homocysteine S-methyltransferase -
  EL086_RS03100 (NCTC8618_03041) - 624065..624319 (+) 255 WP_002886199.1 DUF1912 family protein -
  EL086_RS03105 (NCTC8618_03042) - 624394..624771 (+) 378 WP_038675559.1 helix-hairpin-helix domain-containing protein -
  EL086_RS03110 (NCTC8618_03043) plsY 624889..625530 (-) 642 WP_038675561.1 glycerol-3-phosphate 1-O-acyltransferase PlsY -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 44993.33 Da        Isoelectric Point: 4.3489

>NTDB_id=1119813 EL086_RS03080 WP_002890340.1 619648..620874(+) (clpX) [Streptococcus salivarius strain NCTC8618]
MAGNRNEEMVYCSFCGKNQEEVKKIIAGNGVFICNECVALSQEIIREEMAEEVLADLAETPKPKELLDILNNYVVGQDRA
KRALAVAVYNHYKRINFTESREDNDVDLQKSNILMIGPTGSGKTFLAQTLARSLNVPFAIADATSLTEAGYVGEDVENIL
LKLIQAADFNIERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTKN
ILFIVGGAFDGIEDIVKQRLGEKIIGFGQNNKAIDDDSSYMQEIVAEDIQKFGLIPEFIGRLPVLAALEQLTVDDLVRIL
TEPRNALVKQYQTLLSYDGVELEFDQDALEAIASKAIERKTGARGLRSIIEEVMMDVMFEIPSQEDVTKVRITKEAVDGT
AAPVLETA

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=1119813 EL086_RS03080 WP_002890340.1 619648..620874(+) (clpX) [Streptococcus salivarius strain NCTC8618]
ATGGCTGGAAATCGTAATGAAGAAATGGTTTATTGTTCATTTTGTGGCAAAAACCAAGAAGAAGTAAAGAAAATTATCGC
TGGGAATGGCGTCTTTATCTGTAACGAATGTGTGGCCTTGTCACAAGAAATCATTCGTGAGGAAATGGCAGAAGAAGTTT
TGGCTGACTTGGCTGAAACACCAAAGCCAAAAGAACTTTTGGATATTTTGAACAACTATGTCGTGGGGCAAGACCGTGCT
AAACGTGCCTTGGCGGTAGCTGTTTACAACCACTATAAACGTATCAACTTCACAGAAAGTCGTGAAGACAATGATGTTGA
TTTGCAAAAATCGAATATTCTCATGATTGGACCAACTGGTTCAGGGAAGACTTTCTTGGCTCAGACCTTGGCTCGTAGCT
TGAATGTTCCTTTCGCGATTGCGGATGCGACCTCATTGACAGAGGCAGGTTATGTGGGTGAGGACGTGGAAAATATCCTC
CTCAAACTGATTCAAGCGGCAGACTTCAATATTGAACGTGCGGAACGTGGGATTATCTATGTCGACGAGATTGATAAGAT
TGCTAAAAAAGGTGAAAACGTATCAATCACTCGTGACGTTTCTGGTGAAGGGGTTCAACAAGCCCTCTTGAAGATTATCG
AAGGAACAGTAGCTAGCGTTCCACCTCAAGGTGGCCGTAAACACCCTAACCAAGAGATGATTCAAATTGATACGAAGAAT
ATTCTCTTTATCGTGGGTGGTGCTTTTGATGGTATCGAAGATATCGTTAAGCAACGTCTTGGTGAGAAAATCATTGGTTT
TGGTCAAAATAATAAGGCTATTGATGATGACTCATCATACATGCAAGAAATTGTGGCTGAAGATATCCAAAAATTCGGTC
TTATCCCTGAGTTTATCGGACGTTTGCCAGTCCTTGCTGCCCTTGAACAGTTAACGGTTGACGACTTGGTTCGTATCTTG
ACAGAGCCTAGAAATGCCTTGGTTAAACAGTATCAAACCCTCTTGTCTTATGATGGAGTTGAACTTGAGTTTGACCAAGA
TGCTCTTGAAGCTATTGCAAGTAAGGCAATCGAACGTAAGACTGGTGCACGTGGGCTTCGCTCTATCATTGAAGAAGTCA
TGATGGATGTCATGTTTGAAATTCCTAGCCAGGAAGATGTGACTAAGGTTCGTATTACCAAAGAAGCCGTTGACGGTACA
GCTGCTCCAGTTTTGGAAACAGCGTAA

Domains

Predicted by InterproScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-304)

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-47)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB J7SIE0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

89.976

100

0.902
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

57.606

98.284

0.566

Multiple sequence alignment