Detailed information NTG1119759

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: EL077_RS05405
• Genome accession: NZ_LR134273
• Coordinates: 1148347..1149576 (-)
• Length: 409 a.a.
• NCBI ID: WP_043053130.1
• Uniprot ID: A0A7Z8ZVZ1
• Organism: Streptococcus equi subsp. equi strain NCTC12091
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1143347..1154576

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL077_RS05395 (NCTC12091_01095)	hupY	1144354..1147365 (-)	3012	WP_126436751.1	leucine-rich repeat adhesin HupY/LrrG	-
EL077_RS05400 (NCTC12091_01097)	yihA	1147738..1148337 (-)	600	WP_126437219.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
EL077_RS05405 (NCTC12091_01098)	clpX	1148347..1149576 (-)	1230	WP_043053130.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
EL077_RS05410 (NCTC12091_01099)	-	1149612..1149782 (-)	171	WP_012515696.1	hypothetical protein	-
EL077_RS05415 (NCTC12091_01100)	-	1149802..1150299 (-)	498	WP_126436753.1	dihydrofolate reductase	-
EL077_RS05420 (NCTC12091_01101)	-	1150380..1151219 (-)	840	WP_043025902.1	thymidylate synthase	-
EL077_RS05425 (NCTC12091_01102)	-	1151404..1152579 (+)	1176	WP_126436755.1	hydroxymethylglutaryl-CoA synthase	-
EL077_RS05430 (NCTC12091_01103)	-	1152566..1153849 (+)	1284	WP_337660783.1	hydroxymethylglutaryl-CoA reductase, degradative	-

Sequence

Protein

• Length: 409 a.a.
• Molecular weight: 45157.67 Da
• Isoelectric Point: 4.5698

>NTDB_id=1119759 EL077_RS05405 WP_043053130.1 1148347..1149576(-) (clpX) [Streptococcus equi subsp. equi strain NCTC12091]
MAGNRSNDIKVHCSFCGKSQDEVKKIIAGNNVFICNECVALSQEIIKEELAEEVLADLTEVPKPKELLDILNQYVIGQER
AKRALSVAVYNHYKRISFTESRDDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTK
NILFIVGGAFDGIEEIVKQRLGEKIIGFGQNSRKIDDNASYMQEIIAEDIQKFGLIPEFIGRLPVVAALEQLNTEDLIRI
LTEPRNALVKQYQALLSYDGVELEFEKGALEAIAGRAIERKTGARGLRSIIEETMLDIMFEVPSQEEVTKVRITKEAVEG
QSKPVLEIA

Nucleotide

• Length: 1230 bp

>NTDB_id=1119759 EL077_RS05405 WP_043053130.1 1148347..1149576(-) (clpX) [Streptococcus equi subsp. equi strain NCTC12091]
ATGGCAGGAAATCGTAGTAACGATATTAAGGTTCATTGCTCGTTTTGCGGCAAGAGCCAAGACGAAGTGAAAAAAATTAT
TGCAGGCAACAATGTCTTTATTTGTAATGAATGCGTTGCCTTATCACAAGAAATCATCAAGGAAGAATTGGCAGAAGAGG
TTCTCGCTGATCTGACTGAGGTACCAAAGCCAAAAGAGCTCCTTGATATTTTAAACCAATACGTCATTGGTCAGGAGCGT
GCTAAGAGAGCCTTATCAGTTGCAGTTTATAATCATTACAAGAGGATTTCATTTACTGAGAGTCGTGACGATGATGATGT
GGATTTGCAGAAGTCCAATATTCTGATGATTGGACCAACAGGCTCAGGAAAGACCTTTTTAGCCCAGACTCTGGCTAAGA
GCCTTAATGTTCCATTTGCTATTGCTGATGCAACCTCTTTGACTGAAGCAGGTTATGTCGGAGAGGATGTGGAGAATATC
CTTCTGAAATTAATTCAAGCCGCTGATTACAATGTTGAACGTGCAGAGCGTGGCATTATTTATGTTGATGAAATTGATAA
GATCGCTAAAAAAGGTGAGAATGTCTCTATCACTCGTGATGTATCAGGAGAAGGTGTCCAACAAGCCTTGCTAAAAATTA
TTGAGGGAACGGTTGCTAGTGTTCCACCGCAAGGTGGTCGTAAGCACCCAAACCAAGAGATGATACAGATTGATACCAAA
AATATCTTGTTTATTGTCGGAGGCGCCTTTGATGGTATCGAAGAAATTGTCAAGCAGCGCTTGGGAGAAAAGATCATTGG
CTTTGGGCAAAATAGTCGAAAGATTGATGACAATGCTTCCTATATGCAGGAGATCATTGCTGAGGATATTCAAAAATTTG
GTCTGATTCCCGAATTTATTGGACGCTTGCCTGTTGTAGCAGCGCTTGAGCAGCTTAATACTGAGGATTTGATTCGTATT
TTAACAGAGCCTAGAAATGCTCTTGTGAAGCAATATCAAGCCTTATTGTCATATGATGGCGTAGAGCTTGAGTTTGAAAA
GGGTGCTCTGGAGGCTATTGCAGGCAGGGCTATTGAGCGCAAGACTGGTGCGCGTGGTCTGAGGTCTATTATCGAAGAAA
CCATGCTGGATATCATGTTTGAGGTGCCAAGCCAAGAGGAAGTAACCAAGGTACGCATTACTAAGGAAGCTGTCGAGGGT
CAATCAAAGCCCGTTTTAGAGATAGCCTAG

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (312-390)

• AAA domain (Cdc48 subfamily) (AAA_2) (110-305)

• ClpX C4-type zinc finger (zf-C4_ClpX) (12-48)

3D structure

• AlphaFold DB: A0A7Z8ZVZ1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	88.753	100	0.888
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	59.102	98.044	0.579