Detailed information NTG1119640

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: EL082_RS04415
• Genome accession: NZ_LR134269
• Coordinates: 910329..911372 (+)
• Length: 347 a.a.
• NCBI ID: WP_002466111.1
• Uniprot ID: A0A5F0TYQ0
• Organism: Staphylococcus warneri strain NCTC11044
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 905329..916372

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL082_RS04390 (NCTC11044_00897)	-	906385..907110 (+)	726	WP_002466154.1	type 1 glutamine amidotransferase	-
EL082_RS04395 (NCTC11044_00898)	-	907178..908164 (-)	987	WP_015364857.1	FUSC family protein	-
EL082_RS04400 (NCTC11044_00899)	map	908331..909086 (+)	756	WP_002466104.1	type I methionyl aminopeptidase	-
EL082_RS04405 (NCTC11044_00900)	-	909230..909616 (+)	387	WP_002466133.1	DUF2543 family protein	-
EL082_RS04410 (NCTC11044_00901)	liaF	909631..910332 (+)	702	WP_103286363.1	cell wall-active antibiotics response protein LiaF	-
EL082_RS04415 (NCTC11044_00902)	vraS	910329..911372 (+)	1044	WP_002466111.1	sensor histidine kinase	Regulator
EL082_RS04420 (NCTC11044_00903)	vraR	911362..911991 (+)	630	WP_002466112.1	two-component system response regulator VraR	Regulator
EL082_RS04425 (NCTC11044_00904)	-	912050..913285 (-)	1236	WP_015364859.1	YihY/virulence factor BrkB family protein	-
EL082_RS04430 (NCTC11044_00905)	-	913515..913799 (-)	285	WP_103286364.1	YtxH domain-containing protein	-
EL082_RS04435 (NCTC11044_00906)	-	913806..914270 (-)	465	WP_002466141.1	low molecular weight protein-tyrosine-phosphatase	-
EL082_RS04440 (NCTC11044_00907)	-	914417..914620 (+)	204	WP_002466135.1	DUF1128 domain-containing protein	-
EL082_RS04445 (NCTC11044_00908)	-	914633..915874 (+)	1242	WP_015364860.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40087.57 Da
• Isoelectric Point: 6.2449

>NTDB_id=1119640 EL082_RS04415 WP_002466111.1 910329..911372(+) (vraS) [Staphylococcus warneri strain NCTC11044]
MNHYIRAIGSMLILIYSMLTAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNIIVILLCIIVGSVLAYKINQQNDWIKT
QIERSIEGETVGINDQNIELYSETLEIYHTLVPLNQELHRLRMKTQNLTNENYNMNDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETQLEPPLDQQIPVLEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QEFKVPKGIEDHLFRITQEAISNTLRHSNGTRVTVELFNKQDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYGD

Nucleotide

• Length: 1044 bp

>NTDB_id=1119640 EL082_RS04415 WP_002466111.1 910329..911372(+) (vraS) [Staphylococcus warneri strain NCTC11044]
ATGAATCACTATATAAGAGCTATTGGGTCAATGCTGATATTGATATATAGTATGTTAACGGCGTTCTTATTTATTGATAA
AGTTTTTGTCAACATCATTTACTTTCAAGGAATGTTTTATACACAAATTTTCGGTATTCCAGTGTTCTTATTTTTAAATA
TTATAGTTATATTATTATGTATTATAGTTGGATCAGTTCTAGCATATAAAATTAATCAACAGAATGATTGGATTAAAACT
CAAATTGAGCGATCAATTGAAGGGGAAACTGTTGGAATTAATGATCAAAATATTGAATTGTATAGCGAGACGTTAGAAAT
ATATCATACACTTGTCCCGTTAAATCAAGAGTTACATCGATTAAGAATGAAAACACAAAATTTAACTAACGAAAATTACA
ATATGAATGATGTTAAAGTTAAAAAGATTATTGAAGATGAGCGACAACGCTTAGCTAGAGAATTACATGATTCTGTAAGC
CAACAATTATTCGCTGCGAGTATGATGTTATCTGCAATAAAAGAAACACAGTTAGAACCACCATTAGATCAACAAATACC
CGTACTTGAAAAGATGGTCCAAGATTCACAACTAGAGATGAGAGCATTGTTACTTCATTTAAGACCATTAGGATTAAAAG
ATAAATCATTAGGTGAAGGTATTAAAGATTTAGTCATTGACCTTCAAAAGAAAGTACCAATGAAAGTAGTGCATGAAATT
CAAGAATTTAAAGTGCCAAAAGGAATTGAGGATCATTTATTCAGAATTACACAAGAAGCAATTTCAAATACATTGAGACA
TTCTAATGGCACAAGAGTAACGGTTGAATTATTTAATAAGCAAGATTATCTGCTTTTACGTATACAAGATAATGGTAAAG
GTTTTAATGTAGATGAGAAACTTGAACAAAGTTATGGATTAAAGAATATGCGTGAACGTGCACTAGAAATTGGTGCTACC
TTCCATATCGTATCGTTACCAGACTCTGGTACACGTATTGAAGTTAAAGCACCATTAAACAAGGAGGATTCGTATGGCGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A5F0TYQ0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	94.813	100	0.948