Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   EL071_RS05560 Genome accession   NZ_LR134265
Coordinates   1054315..1055541 (+) Length   408 a.a.
NCBI ID   WP_000918415.1    Uniprot ID   A0A0H1T4M5
Organism   Streptococcus agalactiae strain NCTC8184     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1049315..1060541
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL071_RS05530 - 1049533..1049981 (-) 449 Protein_1013 DUF1836 domain-containing protein -
  EL071_RS05535 (NCTC8184_01095) - 1050073..1051356 (-) 1284 WP_115356690.1 hydroxymethylglutaryl-CoA reductase, degradative -
  EL071_RS05540 (NCTC8184_01096) - 1051358..1052530 (-) 1173 WP_025195382.1 hydroxymethylglutaryl-CoA synthase -
  EL071_RS05545 (NCTC8184_01097) - 1052684..1053523 (+) 840 WP_000158595.1 thymidylate synthase -
  EL071_RS05550 (NCTC8184_01098) - 1053603..1054097 (+) 495 WP_000166043.1 dihydrofolate reductase -
  EL071_RS05555 (NCTC8184_01099) - 1054115..1054285 (+) 171 WP_115356691.1 hypothetical protein -
  EL071_RS05560 (NCTC8184_01100) clpX 1054315..1055541 (+) 1227 WP_000918415.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  EL071_RS05565 (NCTC8184_01101) yihA 1055552..1056148 (+) 597 WP_000796925.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  EL071_RS05570 (NCTC8184_01102) - 1056210..1056758 (-) 549 WP_000140663.1 TetR/AcrR family transcriptional regulator -
  EL071_RS05580 (NCTC8184_01103) - 1056850..1057353 (+) 504 WP_000645480.1 HXXEE domain-containing protein -
  EL071_RS05585 - 1057511..1058192 (+) 682 Protein_1023 HXXEE domain-containing protein -
  EL071_RS05590 (NCTC8184_01106) - 1058322..1059698 (+) 1377 WP_000427485.1 amino acid permease -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 44836.25 Da        Isoelectric Point: 4.4424

>NTDB_id=1119508 EL071_RS05560 WP_000918415.1 1054315..1055541(+) (clpX) [Streptococcus agalactiae strain NCTC8184]
MAGNRNNDMNVYCSFCGKSQDEVKKIIAGNGVFICNECVALSQEIIKEELAEEVLADLAEVPKPKELLEILNQYVVGQDR
AKRALAVAVYNHYKRVSYTESSDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENIL
LKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQINTKN
ILFIVGGAFDGIEDLVKQRLGEKVIGFGQTSRKIDDNASYMQEIISEDIQKFGLIPEFIGRLPVVAALELLTAEDLVRIL
TEPRNALVKQYQTLLSYDGVELEFDQDALLAIADKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVRITKAAVEGT
DKPVLETA

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=1119508 EL071_RS05560 WP_000918415.1 1054315..1055541(+) (clpX) [Streptococcus agalactiae strain NCTC8184]
ATGGCTGGGAATCGTAATAACGATATGAATGTCTATTGTTCATTTTGTGGCAAAAGCCAAGATGAAGTAAAAAAAATTAT
TGCAGGTAATGGTGTTTTCATTTGTAATGAATGTGTGGCCTTATCACAAGAAATTATTAAGGAAGAATTAGCTGAGGAAG
TACTGGCTGATTTAGCAGAAGTACCAAAACCTAAGGAACTATTAGAAATATTAAATCAATATGTTGTAGGGCAAGATCGT
GCTAAACGTGCTTTAGCAGTTGCTGTCTACAATCATTACAAGCGTGTTAGTTATACCGAGAGTAGTGACGATGATGTAGA
TTTGCAAAAATCCAACATTTTGATGATTGGTCCAACTGGCTCAGGAAAAACCTTCTTAGCACAAACACTGGCTAAAAGCC
TTAATGTACCGTTTGCTATTGCAGATGCGACTTCATTGACCGAAGCAGGATACGTTGGAGAAGATGTTGAGAATATTCTT
CTTAAATTGATTCAAGCTGCTGATTATAATGTCGAACGTGCTGAGCGTGGTATTATCTACGTTGATGAAATAGATAAAAT
TGCTAAGAAAGGCGAAAATGTTTCTATCACACGTGATGTGTCTGGTGAAGGTGTACAGCAAGCCCTTCTTAAAATTATTG
AGGGTACGGTAGCAAGTGTTCCCCCACAGGGTGGGCGTAAACATCCTAACCAAGAAATGATTCAAATTAATACCAAGAAC
ATCCTTTTTATTGTCGGTGGTGCTTTTGATGGTATTGAAGACCTTGTGAAGCAACGTTTAGGCGAAAAAGTTATTGGTTT
TGGACAGACAAGCCGTAAAATTGATGACAACGCTTCTTATATGCAAGAGATAATTTCTGAGGATATTCAAAAGTTTGGAC
TGATTCCAGAGTTTATTGGCCGTTTACCAGTAGTTGCAGCGTTAGAACTTCTTACTGCAGAAGATCTGGTTCGTATTCTG
ACAGAACCACGCAATGCTTTGGTTAAACAATACCAAACCTTATTATCTTATGATGGTGTAGAATTGGAATTTGACCAGGA
TGCTCTATTGGCTATCGCTGATAAGGCTATCGAGCGCAAGACTGGTGCACGTGGTTTACGTTCTATTATTGAAGAAACGA
TGCTTGATATCATGTTTGAAATTCCAAGCCAAGAAGATGTAACAAAAGTTCGTATCACAAAGGCTGCTGTTGAGGGTACT
GACAAGCCTGTTTTAGAGACGGCTTAG

Domains

Predicted by InterproScan.

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-304)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-390)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H1T4M5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

90.465

100

0.907
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.25

98.039

0.571

Multiple sequence alignment