Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   EL071_RS02025 Genome accession   NZ_LR134265
Coordinates   385804..388251 (-) Length   815 a.a.
NCBI ID   WP_038406098.1    Uniprot ID   A0AB38VLN8
Organism   Streptococcus agalactiae strain NCTC8184     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 380804..393251
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL071_RS02000 (NCTC8184_00382) - 381085..382341 (+) 1257 WP_115356577.1 toxic anion resistance protein -
  EL071_RS02005 (NCTC8184_00383) hslO 382481..383356 (+) 876 WP_000357828.1 Hsp33 family molecular chaperone HslO -
  EL071_RS02010 (NCTC8184_00384) dusB 383340..384317 (+) 978 WP_000192730.1 tRNA dihydrouridine synthase DusB -
  EL071_RS02015 (NCTC8184_00385) - 384438..385079 (+) 642 WP_000909522.1 deoxynucleoside kinase -
  EL071_RS02020 (NCTC8184_00386) - 385093..385584 (+) 492 WP_000586902.1 GNAT family N-acetyltransferase -
  EL071_RS02025 (NCTC8184_00387) clpC 385804..388251 (-) 2448 WP_038406098.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  EL071_RS02030 (NCTC8184_00388) - 388248..388712 (-) 465 WP_000985641.1 CtsR family transcriptional regulator -
  EL071_RS02035 (NCTC8184_00389) - 388885..389346 (+) 462 WP_115356576.1 small multi-drug export protein -
  EL071_RS02040 (NCTC8184_00390) tsf 389505..390545 (-) 1041 WP_000808080.1 translation elongation factor Ts -
  EL071_RS02045 (NCTC8184_00391) rpsB 390639..391409 (-) 771 WP_000268454.1 30S ribosomal protein S2 -
  EL071_RS02050 (NCTC8184_00392) ahpC 391686..392246 (+) 561 WP_000060538.1 alkyl hydroperoxide reductase subunit C -

Sequence

Protein


Download         Length: 815 a.a.        Molecular weight: 90597.14 Da        Isoelectric Point: 6.0379

>NTDB_id=1119493 EL071_RS02025 WP_038406098.1 385804..388251(-) (clpC) [Streptococcus agalactiae strain NCTC8184]
MSHYSIKLQEVFRLAQFQAARYESHYLESWHLLLAMVLVHDSVAGLTFAEYESEVAIEEYEAATILALGRAPKEEITNYQ
FLEQSPALKKILKLAENISIVVGAEDVGTEHVLLAMLVNKDLLATRILELVGFRGQDDGESVRMVDLRKALERHAGFTKD
DIKAIYELRNPKKAKSGASFSDMMKPPSTAGDLADFTRDLSQMAVDGEIEPVIGRDKEISRMVQVLSRKTKNNPVLVGDA
GVGKTALAYGLAQRIANGNIPYELRDMRVLELDMMSVVAGTRFRGDFEERMNQIIADIEEDGHIILFIDELHTIMGSGSG
IDSTLDAANILKPALARGTLRTVGATTQEEYQKHIEKDAALSRRFAKVLVEEPNLEDAFEILLGLKPAYEAFHNVTISDE
AVMTAVKVAHRYLTSKNLPDSAIDLLDEASATVQMMIKKNAPSLLTEVDQAILDDDMKSASKALKASHKDKKHKPIAVTE
DHIMATLSRLSGIPVEKLTQADSKKYLNLEKELHKRVIGQDDAVTAISRAIRRNQSGIRTGKRPIGSFMFLGPTGVGKTE
LAKALAEVLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLLQV
LDDGVLTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDISHDYTAMQKRIMEELKKAYRPEFINRIDEKVVFHS
LSQDNMREVVKIMVKPLILALKDKGMDLKFQPSALKHLAEDGYDIEMGARPLRRTIQTQVEDHLSELLLANQVKEGQVIK
IGVSKGKLKFDIAKS

Nucleotide


Download         Length: 2448 bp        

>NTDB_id=1119493 EL071_RS02025 WP_038406098.1 385804..388251(-) (clpC) [Streptococcus agalactiae strain NCTC8184]
ATGAGTCATTATTCCATAAAATTACAAGAAGTATTCAGATTGGCGCAATTTCAAGCAGCACGCTATGAAAGTCACTATTT
AGAAAGCTGGCATCTTCTTTTAGCAATGGTTTTAGTTCATGATTCAGTAGCTGGTTTGACATTTGCTGAATATGAGTCTG
AAGTTGCAATTGAAGAGTACGAAGCAGCAACAATTTTAGCTTTAGGTAGAGCACCGAAAGAAGAGATTACCAATTATCAA
TTTTTAGAGCAATCACCAGCTTTGAAAAAGATCTTAAAGTTAGCAGAAAATATTAGTATCGTAGTAGGAGCTGAAGATGT
GGGTACTGAACATGTCTTGCTTGCTATGTTGGTTAATAAAGATTTATTAGCCACACGTATCTTAGAGTTAGTTGGCTTTA
GAGGTCAAGACGATGGTGAATCAGTTCGTATGGTTGATTTACGTAAGGCTCTAGAACGTCATGCCGGTTTTACAAAAGAT
GATATCAAAGCAATTTATGAATTACGTAATCCTAAAAAAGCAAAGTCGGGTGCTTCTTTTTCTGATATGATGAAACCACC
GAGTACTGCTGGTGATTTAGCTGATTTCACACGTGATTTATCACAGATGGCGGTTGATGGGGAAATTGAACCTGTTATTG
GGCGTGATAAAGAAATTTCACGTATGGTCCAAGTCTTAAGTCGTAAAACAAAAAATAATCCTGTCTTAGTTGGAGATGCG
GGTGTCGGTAAAACAGCTTTGGCGTACGGTCTAGCACAACGTATTGCTAATGGAAATATTCCTTATGAGCTTAGAGATAT
GCGTGTTCTAGAGTTAGATATGATGAGCGTTGTTGCTGGAACTCGTTTTCGTGGTGATTTTGAGGAACGTATGAATCAAA
TCATTGCAGATATTGAAGAAGATGGTCATATTATTCTTTTCATTGATGAACTGCATACTATTATGGGTTCTGGCTCTGGT
ATTGATAGCACACTTGATGCTGCTAATATTTTAAAACCAGCTTTGGCTCGAGGCACTTTACGCACTGTTGGAGCAACAAC
TCAAGAGGAATATCAAAAGCATATTGAAAAAGATGCTGCTTTATCTCGTCGCTTTGCAAAAGTTTTAGTAGAAGAACCAA
ATCTTGAAGACGCATTTGAAATTCTACTTGGATTGAAGCCAGCGTATGAAGCCTTTCATAATGTTACTATTTCAGATGAA
GCAGTTATGACTGCTGTAAAAGTGGCTCATCGTTATTTGACAAGTAAGAATTTACCAGACTCAGCTATAGACTTACTTGA
TGAAGCTTCTGCCACTGTGCAAATGATGATTAAGAAAAATGCTCCATCGCTTTTAACAGAAGTTGACCAAGCTATTTTAG
ATGATGATATGAAATCTGCTTCTAAAGCTCTAAAAGCAAGTCATAAGGATAAAAAGCATAAGCCTATTGCCGTAACCGAA
GATCATATTATGGCAACTCTCAGCCGTCTATCTGGTATTCCTGTTGAAAAATTGACACAAGCTGATAGTAAAAAATACCT
CAATTTAGAAAAAGAATTGCATAAACGTGTTATCGGTCAAGATGATGCAGTTACTGCCATTAGTCGTGCTATCCGTCGCA
ATCAATCTGGCATTCGTACTGGTAAGCGTCCTATTGGTTCCTTTATGTTCTTGGGCCCAACTGGTGTTGGTAAGACAGAG
TTAGCAAAAGCCTTGGCAGAAGTGCTGTTTGATGATGAATCAGCCCTAATTCGTTTTGATATGTCGGAATATATGGAAAA
ATTCGCAGCTTCTCGCCTGAATGGGGCACCTCCAGGTTATGTTGGTTATGATGAAGGAGGAGAGCTGACTGAAAAAGTAC
GCAATAAACCATATTCAGTTTTACTTTTTGATGAAGTTGAAAAAGCTCATCCAGATATTTTTAATGTATTATTACAAGTG
CTTGATGATGGCGTTTTAACAGATAGTCGAGGACGAAAAGTTGACTTTTCAAATACTATAATCATTATGACTTCTAATTT
AGGAGCAACTGCATTACGTGACGATAAAACAGTTGGTTTTGGAGCTAAGGATATCAGCCATGATTATACTGCTATGCAAA
AACGTATTATGGAGGAGCTTAAAAAAGCTTATCGACCAGAGTTTATCAATCGTATTGATGAGAAAGTTGTATTCCATAGT
CTCAGCCAAGATAATATGCGTGAAGTTGTGAAAATTATGGTTAAACCTTTAATTTTAGCGCTTAAAGATAAAGGTATGGA
TCTGAAATTCCAGCCTTCAGCCTTGAAACACTTGGCAGAGGATGGCTATGATATAGAAATGGGTGCTCGTCCACTGCGTA
GAACTATTCAAACGCAAGTAGAGGATCATTTATCAGAACTACTATTGGCAAATCAAGTGAAAGAGGGGCAAGTAATTAAG
ATTGGCGTATCCAAAGGCAAATTGAAATTTGATATTGCAAAATCATAA

Domains

Predicted by InterproScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(543-714)

AAA lid domain (AAA_lid_9)

(375-471)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(105-132)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(15-46)

ATPase family associated with various cellular activities (AAA) (AAA)

(235-367)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(721-801)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Streptococcus mutans UA159

76.355

99.632

0.761
  clpC Streptococcus thermophilus LMG 18311

72.883

100

0.729
  clpC Streptococcus thermophilus LMD-9

72.761

100

0.728
  clpC Streptococcus pneumoniae Rx1

68.673

99.877

0.686
  clpC Streptococcus pneumoniae D39

68.673

99.877

0.686
  clpC Streptococcus pneumoniae TIGR4

68.673

99.877

0.686
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

48.554

100

0.494
  clpC Bacillus subtilis subsp. subtilis str. 168

45.564

100

0.466
  clpE Streptococcus mutans UA159

46.395

78.282

0.363

Multiple sequence alignment