Detailed information NTG0111907

Bioinformatically predicted

Overview

• Name: pilD
• Type: Machinery gene
• Locus tag: T556_RS10070
• Genome accession: NZ_CP003974
• Coordinates: 1700966..1701826 (+)
• Length: 286 a.a.
• NCBI ID: WP_003689814.1
• Uniprot ID: A0AA44U9R8
• Organism: Neisseria gonorrhoeae NG-k51.05
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1695966..1706826

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
T556_RS10050 (T556_09335)	dapD	1696476..1697297 (-)	822	WP_003689804.1	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase	-
T556_RS10055 (T556_09340)	pgi	1697507..1699150 (-)	1644	WP_003689806.1	glucose-6-phosphate isomerase	-
T556_RS10065 (T556_09345)	pilG	1699660..1700892 (+)	1233	WP_003689811.1	type 4 pilus assembly protein PilG	Machinery gene
T556_RS10070 (T556_09350)	pilD	1700966..1701826 (+)	861	WP_003689814.1	prepilin peptidase	Machinery gene
T556_RS10075 (T556_09355)	coaE	1701823..1702455 (+)	633	WP_003689816.1	dephospho-CoA kinase	-
T556_RS10080 (T556_09360)	-	1702448..1702657 (+)	210	WP_003696096.1	DNA gyrase inhibitor YacG	-
T556_RS10085 (T556_09365)	pilF	1702743..1704419 (-)	1677	WP_003689817.1	type IV-A pilus assembly ATPase PilB	Machinery gene
T556_RS10100 (T556_09375)	-	1704757..1705203 (-)	447	WP_003689818.1	DUF441 domain-containing protein	-
T556_RS10105 (T556_09380)	-	1705207..1706181 (-)	975	WP_003689819.1	polyprenyl synthetase family protein	-
T556_RS10115 (T556_09385)	rplU	1706405..1706713 (+)	309	WP_003691838.1	50S ribosomal protein L21	-

Sequence

Protein

• Length: 286 a.a.
• Molecular weight: 31332.34 Da
• Isoelectric Point: 8.9561

>NTDB_id=111907 T556_RS10070 WP_003689814.1 1700966..1701826(+) (pilD) [Neisseria gonorrhoeae NG-k51.05]
MSDLSVLSPFAVPLAAVLGLLVGSFLNVVIYRVPVMMERGWTVFAKEHLNLPLTDDESRTFNLMKPDSCCPKCRVPIRAW
QNIPIVSYLLLRGKCASCQTKISIRYPLIELLTGVLFGLVAWQYGWSWITLGGLILTAFLISLTFIDADTQYLPDSMTLP
LIWLGLIFNLDGGFVPLQSAVLGAVAGYSSLWLLCAVYKLLTGKTGMGNGDFKLIAALGAWLGISALPVLIFVSSLIGLV
AAIVMRVAKGRHFAFGPALTVSGWIIFTANDSVWRAVNWWLTHPVR

Nucleotide

• Length: 861 bp

>NTDB_id=111907 T556_RS10070 WP_003689814.1 1700966..1701826(+) (pilD) [Neisseria gonorrhoeae NG-k51.05]
ATGTCTGATTTGTCTGTATTGTCGCCGTTTGCCGTGCCTTTGGCAGCAGTTTTGGGGCTGCTGGTCGGCAGCTTCCTGAA
TGTCGTCATTTACCGCGTACCCGTTATGATGGAACGCGGCTGGACGGTATTTGCCAAAGAACATTTAAACCTGCCGCTGA
CCGACGATGAAAGCCGTACCTTCAACCTGATGAAGCCGGATTCCTGCTGTCCCAAATGCCGTGTGCCGATACGCGCGTGG
CAGAACATCCCGATTGTCAGTTACCTGCTCCTGCGCGGCAAATGCGCTTCCTGCCAAACCAAAATCAGCATACGTTATCC
CTTAATCGAGCTGCTGACCGGCGTATTGTTCGGGCTGGTCGCCTGGCAATACGGCTGGTCTTGGATTACGCTGGGCGGTT
TGATACTGACCGCGTTTCTGATTTCCCTGACCTTTATCGATGCGGACACCCAATACCTGCCCGACTCGATGACATTACCC
TTGATCTGGCTGGGGCTGATATTTAATTTGGACGGCGGCTTCGTGCCTTTGCAGTCTGCCGTTTTAGGTGCGGTTGCCGG
CTATAGTTCATTATGGCTCTTATGTGCAGTGTATAAACTGCTCACAGGAAAAACCGGTATGGGCAACGGAGATTTCAAAC
TGATTGCCGCATTGGGCGCGTGGCTCGGCATATCCGCATTGCCCGTGCTGATTTTTGTTTCCTCTCTGATCGGTTTGGTC
GCGGCAATCGTTATGCGCGTCGCCAAGGGGCGGCATTTTGCCTTCGGCCCCGCACTGACAGTTTCGGGCTGGATAATTTT
TACGGCAAACGATTCCGTATGGCGGGCGGTCAACTGGTGGCTGACCCATCCGGTGAGATGA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (17-124)

• Type IV leader peptidase family (Peptidase_A24) (134-242)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilD	Neisseria gonorrhoeae MS11	100	100	1
pilD	Vibrio cholerae strain A1552	44.792	100	0.451
pilD	Vibrio campbellii strain DS40M4	45.652	96.503	0.441
pilD	Acinetobacter baumannii D1279779	47.727	92.308	0.441
pilD	Acinetobacter nosocomialis M2	47.727	92.308	0.441