Detailed information NTG1118819

Bioinformatically predicted

Overview

• Name: comEC
• Type: Machinery gene
• Locus tag: EL064_RS13010
• Genome accession: NZ_LR134178
• Coordinates: 3004683..3006905 (+)
• Length: 740 a.a.
• NCBI ID: WP_128130164.1
• Uniprot ID: -
• Organism: Legionella sainthelensi strain NCTC12450
• Function: ssDNA transport through the inner membrane (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2999683..3011905

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL064_RS12985 (NCTC12450_02736)	-	2999876..3000499 (-)	624	WP_128130163.1	hypothetical protein	-
EL064_RS18585 (NCTC12450_02737)	-	3000712..3000903 (-)	192	WP_241969459.1	hypothetical protein	-
EL064_RS18590 (NCTC12450_02738)	-	3000872..3001105 (-)	234	WP_338418438.1	extracellular solute-binding protein	-
EL064_RS12990 (NCTC12450_02739)	-	3001032..3001739 (-)	708	WP_241969461.1	spermidine/putrescine ABC transporter substrate-binding protein	-
EL064_RS12995 (NCTC12450_02740)	-	3001736..3002503 (-)	768	WP_115701992.1	ABC transporter permease subunit	-
EL064_RS13000 (NCTC12450_02741)	-	3002500..3003324 (-)	825	WP_115701990.1	ABC transporter permease subunit	-
EL064_RS13005 (NCTC12450_02742)	potA	3003314..3004408 (-)	1095	WP_101901264.1	spermidine/putrescine ABC transporter ATP-binding protein PotA	-
EL064_RS13010 (NCTC12450_02743)	comEC	3004683..3006905 (+)	2223	WP_128130164.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
EL064_RS13015 (NCTC12450_02744)	-	3007016..3008074 (+)	1059	WP_115701986.1	trifunctional transcriptional activator/DNA repair protein Ada/methylated-DNA--[protein]-cysteine S-methyltransferase	-
EL064_RS13020 (NCTC12450_02745)	-	3008410..3008640 (-)	231	WP_027271726.1	hypothetical protein	-
EL064_RS13025 (NCTC12450_02746)	-	3008891..3009460 (+)	570	WP_115701984.1	hypothetical protein	-
EL064_RS13030 (NCTC12450_02747)	-	3009558..3010373 (-)	816	WP_128130165.1	mechanosensitive ion channel family protein	-
EL064_RS13035 (NCTC12450_02748)	-	3010576..3010893 (-)	318	WP_101901269.1	hypothetical protein	-
EL064_RS13040 (NCTC12450_02749)	-	3011148..3011582 (+)	435	WP_241969462.1	group III truncated hemoglobin	-
EL064_RS19235 (NCTC12450_02750)	cydP	3011576..3011746 (+)	171	WP_330987400.1	cytochrome oxidase putative small subunit CydP	-

Sequence

Protein

• Length: 740 a.a.
• Molecular weight: 83763.95 Da
• Isoelectric Point: 9.6999

>NTDB_id=1118819 EL064_RS13010 WP_128130164.1 3004683..3006905(+) (comEC) [Legionella sainthelensi strain NCTC12450]
MEVFCFFIGILYRYTFHGFLPVIIFLICFIIPKYANILFFLLGVLIASLHQSQNLPKGIPDVEVIPQASIEGTIASIPVQ
GSSKTLFVLALEQYDHHPAQGIIQLAWYNKAPKIHAGQRWALNVKLKKPRNYLNPGSMDYVRLLATRHIAWTGYIHSRGN
KLLQKSSSSFNWLELREQLSDQLNLLAPDQQTAGIVEALALNITTHIDPKSWDLFRHTGTTHLFGISGEHIALISGIVYW
LIRWLWTRNARLCLYIPAPYIASIGGLLAALGYAFLAGFAPPVQRALIGCFFYTLYRLGHQRFTAWQVWRYALCGVLWIE
PHAVFMQGFYFSFLAVACLLLTQQRWRFKGFKGSLVLQLSCLIGLMPLTLYWYAYGSINGFIANLFAIPLVGLLIVPLSL
MTMAVSSLSIAKILMKTLSLLIALLFKVLSLTEHLAAVNINCSIYSMELAIVLIGALLMWVLLPIRSFQWIAMLWLLLPF
FPPRTMLQSGEAKIDVLDVGQGLAVVIRTRHHVLLYDTGDRFFQGNDLGKMVILPYLKTLGIKKVDMIVVSHPDKDHLGG
LNSLEREIQVDRLLVNDPHFYHRGLKCHDYPPWQWDGISFRFLPIKTHFTGKNNSSCILQIKTHAGRMLLTGDIEKIAED
YLVQTYGNKLESDVLVVPHHGSKTSSSYRFLLEVAPIYAIASLGFDNRFHFPHAKTLANMKKLSIPFYRTDTCGMVQITL
PVQGPINKPICFSRQRLQPV

Nucleotide

• Length: 2223 bp

>NTDB_id=1118819 EL064_RS13010 WP_128130164.1 3004683..3006905(+) (comEC) [Legionella sainthelensi strain NCTC12450]
ATGGAAGTTTTTTGCTTTTTTATAGGCATATTATATCGATATACCTTTCACGGATTTTTGCCTGTAATTATTTTTTTGAT
TTGTTTCATTATTCCTAAATACGCGAATATTCTGTTTTTTCTTTTAGGTGTCCTCATCGCCTCTCTGCATCAATCACAAA
ATTTACCTAAAGGAATACCCGATGTAGAGGTAATACCTCAAGCAAGTATAGAAGGAACCATTGCATCAATACCAGTCCAA
GGCTCATCTAAGACCCTTTTTGTATTAGCTTTAGAACAATACGACCATCATCCGGCTCAAGGGATAATCCAATTAGCATG
GTACAACAAAGCCCCAAAAATTCATGCAGGACAACGATGGGCACTTAATGTGAAATTAAAAAAGCCGAGAAATTATCTTA
ATCCAGGGAGTATGGATTATGTGCGTTTACTCGCAACTCGCCATATTGCATGGACTGGATATATTCATTCCAGGGGCAAT
AAGTTACTGCAAAAATCCTCTTCATCATTTAATTGGTTAGAACTAAGGGAACAATTAAGTGATCAACTTAATTTATTAGC
ACCTGATCAACAAACCGCTGGGATTGTAGAAGCATTGGCTTTAAATATAACAACCCATATTGACCCCAAAAGCTGGGATT
TATTTAGACATACTGGCACAACCCATTTATTTGGTATTTCGGGTGAACATATCGCCTTAATTTCTGGCATCGTTTATTGG
TTAATCCGTTGGTTATGGACTCGAAACGCTCGTCTTTGTTTATATATTCCAGCTCCTTATATTGCAAGTATCGGTGGTCT
TTTAGCTGCTTTAGGATATGCCTTTTTAGCAGGATTTGCTCCTCCTGTTCAAAGAGCCCTTATCGGATGTTTTTTTTATA
CACTTTATAGGTTGGGTCACCAGCGCTTTACTGCTTGGCAAGTATGGCGATATGCTCTATGTGGTGTTTTATGGATTGAA
CCACATGCAGTATTTATGCAAGGATTCTACTTTTCTTTTCTTGCTGTAGCATGCTTGCTCTTAACGCAACAACGTTGGCG
CTTCAAAGGATTTAAAGGCTCTTTAGTCCTACAGTTAAGCTGTTTAATTGGGTTAATGCCCCTAACCTTATATTGGTATG
CTTATGGTTCCATTAATGGATTTATTGCGAACCTGTTCGCAATACCTTTGGTGGGATTACTCATCGTTCCCCTATCATTA
ATGACTATGGCCGTCAGTTCCTTAAGTATTGCAAAGATACTGATGAAAACCCTTTCTTTGCTCATTGCCTTATTGTTTAA
AGTGCTCTCGCTGACCGAACATTTAGCCGCTGTAAATATTAATTGTTCCATTTACTCTATGGAACTGGCGATTGTACTAA
TAGGGGCTTTATTGATGTGGGTTTTATTACCCATTAGATCTTTTCAATGGATAGCCATGCTTTGGCTACTGCTCCCATTT
TTTCCACCACGAACGATGCTCCAATCAGGTGAAGCCAAAATCGATGTTTTAGATGTGGGACAAGGCTTGGCTGTTGTAAT
TCGAACACGGCACCATGTTTTGCTTTATGATACAGGAGATCGCTTTTTTCAAGGAAATGATTTAGGAAAAATGGTTATTT
TGCCTTATCTTAAAACCCTAGGCATCAAAAAAGTGGATATGATAGTTGTAAGTCATCCTGATAAAGATCATCTTGGAGGA
CTTAATTCACTGGAGAGAGAAATACAAGTAGACAGACTATTGGTCAATGACCCTCATTTCTACCATCGTGGTTTAAAATG
TCATGATTATCCACCATGGCAATGGGATGGTATCTCGTTCCGTTTCTTGCCAATTAAAACTCATTTTACAGGAAAGAACA
ACAGCTCTTGTATTCTACAAATAAAAACACATGCTGGACGTATGCTCTTAACGGGTGATATTGAAAAAATAGCCGAAGAT
TATTTAGTGCAAACTTATGGTAATAAGCTTGAATCAGATGTACTAGTTGTCCCTCATCATGGCAGCAAAACATCATCATC
CTATAGATTTTTATTAGAAGTTGCTCCGATTTATGCTATAGCTTCCTTGGGTTTTGATAATCGCTTTCACTTCCCTCATG
CTAAGACTTTAGCAAACATGAAAAAGTTGAGTATCCCTTTTTACAGAACAGATACGTGTGGCATGGTGCAAATTACTTTA
CCTGTCCAAGGACCAATCAATAAGCCCATTTGCTTTAGTAGACAGCGGTTGCAACCCGTATAA

Domains

Predicted by InterproScan.

• Competence protein (Competence) (201-463)

• Metallo-beta-lactamase superfamily (Lactamase_B) (498-671)

• Domain of unknown function (DUF4131) (DUF4131) (20-157)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC	Legionella pneumophila strain Lp02	63.885	98.784	0.631
comEC	Legionella pneumophila strain ERS1305867	63.475	98.784	0.627