Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   ELZ51_RS08440 Genome accession   NZ_LR134094
Coordinates   1674453..1675778 (-) Length   441 a.a.
NCBI ID   WP_003052142.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae subsp. dysgalactiae strain NCTC4669     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1669453..1680778
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ELZ51_RS08405 (NCTC4669_01781) - 1670059..1670814 (-) 756 WP_126427046.1 hypothetical protein -
  ELZ51_RS08410 (NCTC4669_01782) - 1670825..1671520 (-) 696 WP_126427048.1 ABC transporter ATP-binding protein -
  ELZ51_RS08415 (NCTC4669_01783) - 1671533..1671721 (-) 189 WP_003052131.1 helix-turn-helix transcriptional regulator -
  ELZ51_RS08420 (NCTC4669_01784) - 1671726..1672073 (-) 348 WP_003052134.1 hypothetical protein -
  ELZ51_RS08425 - 1672282..1673233 (+) 952 Protein_1615 IS30 family transposase -
  ELZ51_RS08430 (NCTC4669_01786) hpf 1673188..1673736 (-) 549 WP_003052138.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  ELZ51_RS11645 (NCTC4669_01787) - 1673816..1674481 (-) 666 WP_115246314.1 ComF family protein -
  ELZ51_RS08440 (NCTC4669_01788) comFA/cflA 1674453..1675778 (-) 1326 WP_003052142.1 DEAD/DEAH box helicase Machinery gene
  ELZ51_RS08445 (NCTC4669_01789) - 1675834..1676472 (+) 639 WP_003052144.1 YigZ family protein -
  ELZ51_RS08450 (NCTC4669_01790) cysK 1676576..1677511 (+) 936 WP_126427051.1 cysteine synthase A -
  ELZ51_RS08455 (NCTC4669_01791) - 1677662..1678021 (-) 360 WP_003052148.1 S1 RNA-binding domain-containing protein -
  ELZ51_RS08460 (NCTC4669_01792) - 1678021..1679421 (-) 1401 WP_126427053.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  ELZ51_RS08465 (NCTC4669_01793) - 1679458..1680099 (-) 642 WP_003052152.1 response regulator transcription factor -

Sequence

Protein


Download         Length: 441 a.a.        Molecular weight: 49359.45 Da        Isoelectric Point: 9.6283

>NTDB_id=1118290 ELZ51_RS08440 WP_003052142.1 1674453..1675778(-) (comFA/cflA) [Streptococcus dysgalactiae subsp. dysgalactiae strain NCTC4669]
MEGIENSYGRLFLKHQLPKEVNHLAKTLESIVIIKGKVTCQRCHYQITAEARLPSGTYYCRFCLVFGRNQADRPLYYIPP
HPFPIANYLQWKGILTPYQESISNQLVKNVHAKKPTLVHAVTGAGKTEMIYGAIAAVVNAGGWVCLASPRVDVCIELANR
LKAAFSCRVTLLHADSEAYQRSPIIVATTHQLLTFYKAFDLLIIDEVDAFPFVNNHQLQYASQQAAKEGASSIVLTATST
KELEEQVKSGELEKLTLARRFHDNPLILPKFIRSFGLLKKIHCQKLPRALVKSISQQRKTGCPLLIFLPIIAMAELVTEL
LKLAFPEEQIACVSSQSADRVKDIDDFRQGKKGILVTTTILERGVTFPGVDVFVLMAQHRGYSSQSLVQIAGRVGRSIER
PTGKVYFFHDGISQAMRNARKEIKEMNQKGYSNDMPPMSTI

Nucleotide


Download         Length: 1326 bp        

>NTDB_id=1118290 ELZ51_RS08440 WP_003052142.1 1674453..1675778(-) (comFA/cflA) [Streptococcus dysgalactiae subsp. dysgalactiae strain NCTC4669]
ATGGAAGGTATTGAAAACAGTTACGGTCGTTTATTTTTAAAACATCAATTGCCAAAAGAAGTAAATCATCTGGCAAAGAC
CTTGGAAAGTATAGTAATCATAAAAGGTAAAGTCACTTGTCAACGCTGTCATTATCAGATAACCGCAGAAGCGAGATTAC
CAAGCGGCACTTACTACTGTCGCTTCTGTCTCGTTTTTGGCCGAAATCAAGCTGATAGGCCTCTTTATTATATACCTCCA
CATCCTTTTCCTATAGCCAATTATCTTCAATGGAAGGGGATATTAACACCCTACCAAGAAAGTATTTCAAACCAATTAGT
CAAGAATGTTCATGCTAAAAAACCTACTTTAGTGCATGCTGTTACCGGAGCCGGCAAGACAGAGATGATTTATGGTGCCA
TAGCAGCAGTTGTTAATGCTGGAGGTTGGGTTTGTTTAGCTAGCCCAAGGGTCGATGTTTGTATAGAACTTGCTAATCGC
TTAAAAGCTGCTTTTTCTTGCCGAGTTACTCTTTTACACGCTGACTCAGAAGCTTATCAAAGAAGTCCTATTATAGTAGC
TACTACCCATCAATTACTGACCTTTTATAAGGCTTTTGATCTTTTAATCATTGATGAAGTTGATGCTTTTCCTTTTGTCA
ATAATCATCAACTACAATATGCATCGCAGCAAGCCGCTAAAGAAGGCGCTAGTAGTATCGTATTGACCGCGACATCGACC
AAAGAACTGGAAGAGCAGGTCAAAAGTGGGGAATTAGAGAAGTTGACATTAGCTAGACGATTTCATGATAATCCTTTGAT
TCTTCCGAAATTTATCAGGAGTTTTGGCCTATTAAAAAAAATTCACTGTCAAAAACTTCCTCGAGCTCTTGTTAAATCTA
TCAGTCAACAAAGGAAAACAGGATGTCCACTGCTAATTTTTCTTCCTATTATTGCCATGGCAGAATTAGTTACTGAATTA
TTAAAGTTAGCTTTTCCAGAGGAGCAAATTGCCTGTGTCTCTAGCCAATCAGCTGACAGAGTTAAAGACATTGATGACTT
TCGTCAAGGAAAGAAAGGCATTTTGGTGACCACCACAATATTGGAAAGGGGTGTTACTTTCCCAGGTGTGGATGTCTTTG
TGCTTATGGCACAGCATCGAGGATACAGTTCTCAAAGCTTGGTTCAAATCGCAGGTCGTGTCGGGAGATCTATCGAAAGG
CCAACAGGAAAGGTGTATTTCTTTCACGATGGGATTAGCCAAGCAATGCGCAATGCAAGAAAAGAAATTAAAGAAATGAA
TCAGAAAGGTTATTCGAATGATATGCCTCCTATGTCAACAATTTAG

Domains

Predicted by InterproScan.

DEAD/DEAH box helicase (DEAD)

(99-244)

Helicase conserved C-terminal domain (Helicase_C)

(289-396)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

53.081

95.692

0.508
  comFA/cflA Streptococcus pneumoniae D39

53.081

95.692

0.508
  comFA/cflA Streptococcus pneumoniae R6

53.081

95.692

0.508
  comFA/cflA Streptococcus pneumoniae TIGR4

53.081

95.692

0.508
  comFA/cflA Streptococcus mitis NCTC 12261

51.628

97.506

0.503
  comFA/cflA Streptococcus mitis SK321

51.765

96.372

0.499
  comFA Lactococcus lactis subsp. cremoris KW2

45.366

92.971

0.422
  comFA Latilactobacillus sakei subsp. sakei 23K

37.355

97.732

0.365

Multiple sequence alignment