Detailed information    

insolico Bioinformatically predicted

Overview

Name   eeP   Type   Regulator
Locus tag   ELZ51_RS01375 Genome accession   NZ_LR134094
Coordinates   243021..244280 (+) Length   419 a.a.
NCBI ID   WP_126425746.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae subsp. dysgalactiae strain NCTC4669     
Function   processing of ComS (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 233483..279417 243021..244280 within 0


Gene organization within MGE regions


Location: 233483..279417
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ELZ51_RS01340 (NCTC4669_00285) dexB 233818..235425 (+) 1608 WP_126427584.1 glucan 1,6-alpha-glucosidase DexB -
  ELZ51_RS01345 (NCTC4669_00286) - 236100..239723 (+) 3624 WP_126425742.1 pullulanase -
  ELZ51_RS01350 (NCTC4669_00287) - 239877..240167 (-) 291 WP_003049487.1 hypothetical protein -
  ELZ51_RS01355 (NCTC4669_00288) - 240323..240673 (+) 351 WP_126425744.1 thioredoxin domain-containing protein -
  ELZ51_RS01360 (NCTC4669_00289) yajC 240780..241139 (+) 360 WP_003049492.1 preprotein translocase subunit YajC -
  ELZ51_RS01365 (NCTC4669_00290) - 241367..242116 (+) 750 WP_003049494.1 isoprenyl transferase -
  ELZ51_RS01370 (NCTC4669_00291) - 242129..242923 (+) 795 WP_003049495.1 phosphatidate cytidylyltransferase -
  ELZ51_RS01375 (NCTC4669_00292) eeP 243021..244280 (+) 1260 WP_126425746.1 RIP metalloprotease RseP Regulator
  ELZ51_RS01380 (NCTC4669_00293) - 244472..246328 (+) 1857 WP_003049499.1 proline--tRNA ligase -
  ELZ51_RS01385 (NCTC4669_00294) - 246381..246938 (+) 558 WP_037584902.1 nucleotidyltransferase family protein -
  ELZ51_RS01390 (NCTC4669_00295) - 247055..251452 (+) 4398 WP_115252548.1 PolC-type DNA polymerase III -
  ELZ51_RS01395 (NCTC4669_00296) - 251618..252046 (+) 429 WP_126425748.1 MarR family winged helix-turn-helix transcriptional regulator -
  ELZ51_RS01400 (NCTC4669_00297) - 252132..252683 (+) 552 WP_126425751.1 NADPH-dependent FMN reductase -
  ELZ51_RS01405 (NCTC4669_00298) def 252751..253365 (-) 615 WP_003049509.1 peptide deformylase -
  ELZ51_RS01410 (NCTC4669_00299) - 253665..254330 (-) 666 WP_126425753.1 cyclic nucleotide-binding domain-containing protein -
  ELZ51_RS01415 - 254421..255602 (+) 1182 Protein_236 MFS transporter -
  ELZ51_RS01420 (NCTC4669_00302) rpsO 255750..256019 (+) 270 WP_003046456.1 30S ribosomal protein S15 -
  ELZ51_RS01425 (NCTC4669_00303) - 256371..258431 (+) 2061 WP_126425755.1 BglG family transcription antiterminator -
  ELZ51_RS01430 (NCTC4669_00304) - 258424..258708 (+) 285 WP_002982644.1 PTS sugar transporter subunit IIB -
  ELZ51_RS01435 (NCTC4669_00305) - 258735..260114 (+) 1380 WP_126425757.1 PTS ascorbate transporter subunit IIC -
  ELZ51_RS01440 (NCTC4669_00306) - 260124..260855 (+) 732 WP_126425759.1 transaldolase -
  ELZ51_RS01445 pnp 261133..263277 (+) 2145 WP_126425761.1 polyribonucleotide nucleotidyltransferase -
  ELZ51_RS01450 (NCTC4669_00308) - 263270..264022 (+) 753 WP_115246740.1 SseB family protein -
  ELZ51_RS01455 (NCTC4669_00309) cysE 264031..264615 (+) 585 WP_126425763.1 serine O-acetyltransferase -
  ELZ51_RS01460 (NCTC4669_00310) - 264865..265095 (+) 231 WP_126425765.1 hypothetical protein -
  ELZ51_RS01465 (NCTC4669_00311) cysS 265123..266466 (+) 1344 WP_126425767.1 cysteine--tRNA ligase -
  ELZ51_RS01470 (NCTC4669_00312) - 266459..266860 (+) 402 WP_126425769.1 Mini-ribonuclease 3 -
  ELZ51_RS01475 (NCTC4669_00313) - 267194..267979 (+) 786 WP_126425771.1 hypothetical protein -
  ELZ51_RS01480 (NCTC4669_00314) rlmB 268027..268773 (+) 747 WP_126425773.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  ELZ51_RS01485 (NCTC4669_00315) - 268777..269295 (+) 519 WP_003049554.1 NYN domain-containing protein -
  ELZ51_RS01490 (NCTC4669_00316) - 269391..270251 (+) 861 WP_126425775.1 DegV family protein -
  ELZ51_RS01495 (NCTC4669_00317) - 270387..271085 (+) 699 WP_126425778.1 hypothetical protein -
  ELZ51_RS01500 (NCTC4669_00318) - 271082..271288 (+) 207 WP_126425780.1 helix-turn-helix transcriptional regulator -
  ELZ51_RS01505 (NCTC4669_00320) rplM 271506..271952 (+) 447 WP_002982710.1 50S ribosomal protein L13 -
  ELZ51_RS01510 (NCTC4669_00321) rpsI 271973..272365 (+) 393 WP_126425782.1 30S ribosomal protein S9 -
  ELZ51_RS01515 (NCTC4669_00322) - 272422..273072 (-) 651 Protein_256 site-specific integrase -
  ELZ51_RS01520 - 273113..274219 (-) 1107 Protein_257 IS3-like element ISSdy1 family transposase -
  ELZ51_RS01525 (NCTC4669_00326) - 274289..274663 (-) 375 Protein_258 hypothetical protein -
  ELZ51_RS11655 - 274630..274728 (-) 99 Protein_259 DNA-binding protein -
  ELZ51_RS01535 (NCTC4669_00327) - 274721..275305 (-) 585 WP_126425784.1 replication protein -
  ELZ51_RS01540 (NCTC4669_00328) - 275438..276052 (-) 615 WP_126425786.1 hypothetical protein -
  ELZ51_RS01545 (NCTC4669_00329) - 276054..277130 (-) 1077 WP_126427586.1 ATP-binding cassette domain-containing protein -
  ELZ51_RS01550 (NCTC4669_00330) - 277130..277444 (-) 315 WP_126425788.1 hypothetical protein -
  ELZ51_RS01555 (NCTC4669_00331) - 277646..278557 (+) 912 WP_126425790.1 hypothetical protein -

Sequence

Protein


Download         Length: 419 a.a.        Molecular weight: 45608.21 Da        Isoelectric Point: 8.9664

>NTDB_id=1118258 ELZ51_RS01375 WP_126425746.1 243021..244280(+) (eeP) [Streptococcus dysgalactiae subsp. dysgalactiae strain NCTC4669]
MLGIITFIIIFGILVIVHEFGHFYFAKKSGILVREFAIGMGPKIFSHVDQEGTLYTLRILPLGGYVRMAGWGDDKTEIKT
GTPASLTLNEQGSVKRINLSQSKIDPTSLPMNVTSYDLEDDLSITGLVLDETKTYAVDHNATIVEEDGTEIRIAPLDVQY
QNASIGGRLITNFAGPMNNFILGIVVFILLVFLQGGMPDFSSNQVRVQENGAAAKAGIRDNDRIVTINGHKVKDWADLTE
AVQASTRNLGASETVKVTYKSGQTLKTVAVKPQKQGKQYALGVKARLKTGFVDKLLGGLELAWNGAFAILNVLKGLITAF
SLNKLGGPVAMYQMSNQAAQNGLDSVLSLMAMLSINLGIFNLIPIPALDGGKILMNIIEAIRRKPLKQETETYITLVGVA
IMVVLMIAVTWNDIMRAFF

Nucleotide


Download         Length: 1260 bp        

>NTDB_id=1118258 ELZ51_RS01375 WP_126425746.1 243021..244280(+) (eeP) [Streptococcus dysgalactiae subsp. dysgalactiae strain NCTC4669]
ATGTTAGGAATAATAACCTTTATTATTATTTTTGGGATTTTAGTCATTGTCCATGAATTTGGGCATTTCTATTTTGCCAA
AAAATCTGGGATTCTTGTCAGAGAATTTGCCATTGGTATGGGCCCCAAAATCTTTTCGCATGTTGACCAAGAAGGGACTC
TCTACACTTTGAGGATTTTGCCTTTGGGTGGTTACGTGCGTATGGCTGGTTGGGGAGATGACAAGACAGAAATCAAGACT
GGGACACCGGCTAGCTTGACACTAAATGAGCAAGGGTCGGTAAAGCGCATCAACTTGTCTCAAAGTAAGATTGATCCCAC
TAGCCTGCCCATGAATGTCACTTCCTATGATTTGGAAGATGACCTTAGTATCACCGGTTTGGTTTTGGATGAGACCAAGA
CCTATGCTGTTGACCATAATGCGACCATTGTTGAAGAAGATGGTACTGAGATTCGAATCGCTCCGCTTGATGTGCAGTAC
CAAAATGCTAGCATTGGTGGCCGCTTAATCACCAACTTTGCTGGTCCTATGAATAACTTTATTCTAGGGATTGTGGTCTT
TATCCTTCTTGTCTTTTTACAAGGTGGCATGCCAGATTTTAGTAGCAATCAAGTCCGTGTGCAAGAAAATGGTGCCGCTG
CTAAAGCTGGTATCCGCGACAATGACCGGATTGTAACTATCAATGGTCATAAGGTCAAGGATTGGGCAGATTTGACCGAA
GCTGTCCAAGCGTCTACTCGCAACCTAGGTGCTTCCGAAACGGTTAAGGTGACTTACAAATCAGGTCAAACCCTAAAAAC
CGTCGCTGTTAAGCCTCAAAAACAAGGCAAGCAATATGCTCTAGGTGTGAAGGCAAGGTTGAAAACAGGTTTTGTTGATA
AGCTCCTAGGCGGTTTAGAATTGGCTTGGAATGGTGCTTTTGCTATTTTGAATGTCTTGAAAGGTCTGATCACTGCCTTT
AGCTTAAATAAGCTAGGTGGTCCAGTTGCCATGTACCAAATGTCTAATCAGGCTGCCCAAAATGGCTTAGATTCTGTCTT
ATCTCTCATGGCAATGCTCTCTATCAACTTGGGAATTTTCAACTTAATTCCCATCCCTGCCCTTGATGGTGGGAAAATCT
TGATGAATATTATTGAAGCCATTCGTCGCAAACCTTTGAAACAAGAAACAGAAACCTATATCACTCTTGTTGGGGTTGCC
ATCATGGTTGTTCTGATGATTGCCGTGACGTGGAATGATATTATGCGAGCTTTCTTCTAA

Domains

Predicted by InterproScan.

Peptidase family M50 (Peptidase_M50)

(6-405)

PDZ domain (PDZ_2)

(206-271)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  eeP Streptococcus thermophilus LMG 18311

69.359

100

0.697
  eeP Streptococcus thermophilus LMD-9

69.121

100

0.695

Multiple sequence alignment