Detailed information NTG1118225

Bioinformatically predicted

Overview

• Name: comGF
• Type: Machinery gene
• Locus tag: ELZ56_RS07940
• Genome accession: NZ_LR134093
• Coordinates: 1612521..1613018 (-)
• Length: 165 a.a.
• NCBI ID: WP_001794055.1
• Uniprot ID: A0A7U7EV69
• Organism: Staphylococcus aureus strain NCTC11965
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1607521..1618018

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ELZ56_RS07915 (NCTC11965_01496)	gcvPB	1607683..1609155 (-)	1473	WP_000202178.1	aminomethyl-transferring glycine dehydrogenase subunit GcvPB	-
ELZ56_RS07920 (NCTC11965_01497)	gcvPA	1609148..1610494 (-)	1347	WP_000019697.1	aminomethyl-transferring glycine dehydrogenase subunit GcvPA	-
ELZ56_RS07925 (NCTC11965_01498)	gcvT	1610514..1611605 (-)	1092	WP_000093347.1	glycine cleavage system aminomethyltransferase GcvT	-
ELZ56_RS07930	-	1611764..1612288 (-)	525	WP_001015125.1	shikimate kinase	-
ELZ56_RS07935	-	1612278..1612424 (-)	147	WP_001789879.1	hypothetical protein	-
ELZ56_RS07940 (NCTC11965_01500)	comGF	1612521..1613018 (-)	498	WP_001794055.1	competence type IV pilus minor pilin ComGF	Machinery gene
ELZ56_RS07945 (NCTC11965_01501)	comGE	1612936..1613235 (-)	300	WP_000844413.1	hypothetical protein	Machinery gene
ELZ56_RS07950 (NCTC11965_01502)	comGD	1613222..1613668 (-)	447	WP_001791207.1	competence type IV pilus minor pilin ComGD	Machinery gene
ELZ56_RS07955 (NCTC11965_01503)	comGC	1613646..1613957 (-)	312	WP_000472257.1	competence type IV pilus major pilin ComGC	Machinery gene
ELZ56_RS07960 (NCTC11965_01504)	comGB	1613971..1615041 (-)	1071	WP_000776412.1	competence type IV pilus assembly protein ComGB	Machinery gene
ELZ56_RS07965 (NCTC11965_01505)	comGA	1615013..1615987 (-)	975	WP_000697220.1	competence type IV pilus ATPase ComGA	Machinery gene
ELZ56_RS07970 (NCTC11965_01506)	-	1616039..1616662 (-)	624	WP_001223008.1	MBL fold metallo-hydrolase	-
ELZ56_RS07975 (NCTC11965_01507)	-	1616659..1616988 (-)	330	WP_001018871.1	MTH1187 family thiamine-binding protein	-
ELZ56_RS07980 (NCTC11965_01508)	-	1616988..1617974 (-)	987	WP_000161314.1	ROK family glucokinase	-

Sequence

Protein

• Length: 165 a.a.
• Molecular weight: 19224.98 Da
• Isoelectric Point: 10.2192

>NTDB_id=1118225 ELZ56_RS07940 WP_001794055.1 1612521..1613018(-) (comGF) [Staphylococcus aureus strain NCTC11965]
MILSKVTNKFVLFQKIPLLIKRHVYSINVKAFSLIEMLVAMMVISITLLIVPDLIRLNKTFLIESRELTTVDFEFFSRDI
LEDFKGVDRNDIEIRQQRIILHKGEEMIEYKLINNKIIKVVNDRGNITMINNVTAFTANIYYKSIIKITITVKVGTNLQT
KTIYV

Nucleotide

• Length: 498 bp

>NTDB_id=1118225 ELZ56_RS07940 WP_001794055.1 1612521..1613018(-) (comGF) [Staphylococcus aureus strain NCTC11965]
ATGATATTAAGCAAAGTGACCAACAAATTTGTGCTATTTCAAAAAATACCACTTCTTATCAAAAGACATGTATACAGTAT
TAATGTCAAAGCTTTTTCGCTAATTGAAATGTTAGTAGCGATGATGGTTATAAGTATAACTTTACTAATTGTTCCAGACT
TAATTAGACTTAACAAAACTTTTCTAATTGAAAGTAGGGAATTAACAACTGTAGATTTCGAATTTTTCTCAAGAGATATT
CTAGAGGATTTTAAAGGTGTAGATAGAAACGATATTGAAATTAGGCAACAGCGTATCATTTTACATAAAGGTGAAGAAAT
GATCGAATACAAATTAATAAATAATAAAATTATTAAAGTTGTAAATGACAGAGGAAATATAACAATGATTAATAATGTTA
CAGCATTTACTGCAAATATCTACTATAAATCTATTATTAAAATAACGATAACAGTTAAAGTCGGTACAAATCTGCAGACT
AAAACAATTTATGTATAA

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (28-51)

• Putative Competence protein ComGF (ComGF) (68-155)

3D structure

• AlphaFold DB: A0A7U7EV69

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF	Staphylococcus aureus N315	98.182	100	0.982
comGF	Staphylococcus aureus MW2	96.97	100	0.97