Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   ELZ48_RS04645 Genome accession   NZ_LR134089
Coordinates   968319..968948 (+) Length   209 a.a.
NCBI ID   WP_002482846.1    Uniprot ID   A0A380HJV9
Organism   Staphylococcus saprophyticus strain NCTC7666     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 963319..973948
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ELZ48_RS04620 (NCTC7666_00962) - 964168..965154 (-) 987 WP_002482841.1 FUSC family protein -
  ELZ48_RS04625 (NCTC7666_00963) map 965329..966081 (+) 753 WP_126424455.1 type I methionyl aminopeptidase -
  ELZ48_RS04630 (NCTC7666_00964) - 966185..966571 (+) 387 WP_041079966.1 hypothetical protein -
  ELZ48_RS04635 (NCTC7666_00965) liaF 966588..967289 (+) 702 WP_011302780.1 cell wall-active antibiotics response protein LiaF -
  ELZ48_RS04640 (NCTC7666_00966) vraS 967286..968329 (+) 1044 WP_011302781.1 sensor histidine kinase Regulator
  ELZ48_RS04645 (NCTC7666_00967) vraR 968319..968948 (+) 630 WP_002482846.1 response regulator transcription factor Regulator
  ELZ48_RS04650 (NCTC7666_00968) - 969105..970277 (-) 1173 WP_002482847.1 YihY/virulence factor BrkB family protein -
  ELZ48_RS04655 (NCTC7666_00969) - 970689..970973 (-) 285 WP_002482848.1 hypothetical protein -
  ELZ48_RS04660 (NCTC7666_00970) - 970980..971444 (-) 465 WP_011302783.1 low molecular weight protein-tyrosine-phosphatase -
  ELZ48_RS04665 (NCTC7666_00971) - 971579..971782 (+) 204 WP_002482850.1 DUF1128 family protein -
  ELZ48_RS04670 (NCTC7666_00972) - 971796..973034 (+) 1239 WP_115338454.1 aminopeptidase -
  ELZ48_RS04675 (NCTC7666_00973) - 973248..973769 (+) 522 WP_037538134.1 acyl-CoA thioesterase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23684.19 Da        Isoelectric Point: 4.6997

>NTDB_id=1118077 ELZ48_RS04645 WP_002482846.1 968319..968948(+) (vraR) [Staphylococcus saprophyticus strain NCTC7666]
MPIKVLFVDDHEMVRIGISSYLSTQSDIDVVGEGKSGKDAIEKAHELKPDLILMDLLMDDMDGVEATEQVKKDLPNIKVV
MLTSYIEDNEVYRALDSGVDSYILKTTSASDIAEAIRKTYNNESVFEAEVLVKMRNRMKQRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=1118077 ELZ48_RS04645 WP_002482846.1 968319..968948(+) (vraR) [Staphylococcus saprophyticus strain NCTC7666]
ATGCCGATTAAAGTATTATTTGTTGATGATCATGAAATGGTTCGAATAGGTATTTCTAGTTATTTATCCACACAATCTGA
TATAGATGTCGTAGGGGAAGGTAAGTCAGGAAAAGATGCAATCGAAAAAGCACATGAACTGAAACCGGACCTAATTTTAA
TGGATTTACTTATGGACGATATGGATGGTGTCGAAGCAACTGAACAAGTTAAAAAAGACTTGCCAAATATTAAAGTTGTC
ATGCTTACGAGTTATATTGAAGATAACGAAGTCTATCGTGCACTTGATTCCGGTGTAGATAGCTATATATTGAAAACAAC
AAGTGCTAGTGATATTGCTGAAGCGATTCGTAAGACTTACAATAATGAGTCAGTATTTGAAGCAGAAGTCCTAGTTAAAA
TGAGAAATAGGATGAAACAACGAGCTGAATTGTATGAAATGCTCACAGAACGTGAAATGGAGATTTTATTACTGATTGCT
AAAGGTTACTCTAACCAAGAGATTGCCAGCGCTTCACATATTACGATTAAAACAGTGAAAACGCATGTAAGTAATATCCT
AAGTAAATTAGAAGTTCAAGATAGAACTCAAGCCGTCATATATGCATTCCAGCACAATTTAATTCAATAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, luxR family (GerE)

(147-202)

Response regulator receiver domain (Response_reg)

(5-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A380HJV9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

89.952

100

0.9

Multiple sequence alignment