Detailed information NTG1118076

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: ELZ48_RS04640
• Genome accession: NZ_LR134089
• Coordinates: 967286..968329 (+)
• Length: 347 a.a.
• NCBI ID: WP_011302781.1
• Uniprot ID: -
• Organism: Staphylococcus saprophyticus strain NCTC7666
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 962286..973329

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ELZ48_RS04615 (NCTC7666_00961)	-	963310..964029 (+)	720	WP_115338453.1	type 1 glutamine amidotransferase	-
ELZ48_RS04620 (NCTC7666_00962)	-	964168..965154 (-)	987	WP_002482841.1	FUSC family protein	-
ELZ48_RS04625 (NCTC7666_00963)	map	965329..966081 (+)	753	WP_126424455.1	type I methionyl aminopeptidase	-
ELZ48_RS04630 (NCTC7666_00964)	-	966185..966571 (+)	387	WP_041079966.1	hypothetical protein	-
ELZ48_RS04635 (NCTC7666_00965)	liaF	966588..967289 (+)	702	WP_011302780.1	cell wall-active antibiotics response protein LiaF	-
ELZ48_RS04640 (NCTC7666_00966)	vraS	967286..968329 (+)	1044	WP_011302781.1	sensor histidine kinase	Regulator
ELZ48_RS04645 (NCTC7666_00967)	vraR	968319..968948 (+)	630	WP_002482846.1	response regulator transcription factor	Regulator
ELZ48_RS04650 (NCTC7666_00968)	-	969105..970277 (-)	1173	WP_002482847.1	YihY/virulence factor BrkB family protein	-
ELZ48_RS04655 (NCTC7666_00969)	-	970689..970973 (-)	285	WP_002482848.1	hypothetical protein	-
ELZ48_RS04660 (NCTC7666_00970)	-	970980..971444 (-)	465	WP_011302783.1	low molecular weight protein-tyrosine-phosphatase	-
ELZ48_RS04665 (NCTC7666_00971)	-	971579..971782 (+)	204	WP_002482850.1	DUF1128 family protein	-
ELZ48_RS04670 (NCTC7666_00972)	-	971796..973034 (+)	1239	WP_115338454.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40050.55 Da
• Isoelectric Point: 6.4221

>NTDB_id=1118076 ELZ48_RS04640 WP_011302781.1 967286..968329(+) (vraS) [Staphylococcus saprophyticus strain NCTC7666]
MNHYFRAIGSMLILVYSTFFAIFFIDKVFVNIMYFQGMFYTQIFGIPVLLFLNLMVILLCIIVGSVLAYKINQQNHWLKD
QIERSIEGQTVGINDQNIELYNETIELYQTLVPLNQEVHKLRMKTQNLTNESYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETELKAPLDQQIPVLEKMIQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVVDLQKKVPMKVVHDI
EEFKVPKGIEDHLFRITQEAISNTLRHSKGTKVTIELFNREEYLLLRIQDNGKGFNVDDKVEQSYGLKNMRERALEIGAT
FHIVSLPDAGTRIEVKAPLNKEDSNAD

Nucleotide

• Length: 1044 bp

>NTDB_id=1118076 ELZ48_RS04640 WP_011302781.1 967286..968329(+) (vraS) [Staphylococcus saprophyticus strain NCTC7666]
ATGAATCACTACTTTAGAGCGATCGGGTCCATGTTGATATTAGTATATAGTACGTTTTTTGCCATATTCTTTATTGATAA
AGTGTTTGTTAATATAATGTATTTTCAAGGTATGTTTTATACTCAAATATTTGGCATACCTGTACTGCTTTTTTTAAATC
TAATGGTGATTTTACTCTGTATTATTGTAGGTTCTGTCTTAGCATATAAAATCAATCAGCAAAATCATTGGTTAAAAGAT
CAAATTGAACGTTCAATAGAAGGTCAAACAGTGGGTATCAATGATCAAAATATTGAATTATACAACGAAACAATCGAACT
ATATCAAACGCTTGTGCCGTTAAATCAAGAAGTACATAAATTAAGAATGAAAACACAGAACCTGACGAATGAATCTTATA
ATATCAATGATGTTAAAGTTAAGAAAATTATAGAAGACGAACGTCAACGTTTAGCGCGTGAATTACATGATTCAGTTAGT
CAACAATTATTCGCAGCAAGTATGATGTTATCAGCAATTAAAGAGACAGAATTGAAGGCCCCATTGGACCAACAAATACC
AGTATTAGAAAAAATGATTCAAGATTCCCAATTAGAAATGAGAGCACTACTATTACACTTAAGACCTATTGGTTTGAAAG
ATAAATCTTTAGGTGAGGGTATTAAAGATTTAGTCGTTGATTTACAGAAAAAAGTACCAATGAAAGTGGTACATGATATT
GAAGAATTCAAAGTACCAAAAGGTATCGAGGACCATTTATTCCGTATTACGCAAGAAGCCATTTCTAATACGCTAAGACA
TTCTAAAGGAACGAAGGTCACAATTGAATTATTTAATAGGGAAGAATATTTGTTATTGCGTATACAAGATAATGGTAAAG
GGTTTAATGTAGATGATAAGGTAGAACAAAGTTATGGATTAAAAAATATGCGCGAACGTGCACTAGAAATAGGTGCAACA
TTTCATATCGTTTCTTTGCCTGATGCAGGTACGAGAATTGAAGTGAAGGCACCATTAAATAAGGAGGATTCAAATGCCGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	87.32	100	0.873