Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   ELZ47_RS06380 Genome accession   NZ_LR134002
Coordinates   1239328..1240557 (-) Length   409 a.a.
NCBI ID   WP_002917310.1    Uniprot ID   A0A3R9GT11
Organism   Streptococcus sanguinis strain NCTC 10904     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1234328..1245557
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ELZ47_RS06350 (NCTC10904_01248) - 1234647..1235276 (-) 630 WP_002895573.1 hypothetical protein -
  ELZ47_RS06355 (NCTC10904_01249) - 1235383..1235724 (-) 342 WP_125331009.1 hypothetical protein -
  ELZ47_RS06360 (NCTC10904_01250) - 1235962..1236759 (-) 798 WP_002904443.1 formate/nitrite transporter family protein -
  ELZ47_RS06365 (NCTC10904_01251) mmuM 1236873..1237820 (-) 948 WP_126435603.1 homocysteine S-methyltransferase -
  ELZ47_RS06370 (NCTC10904_01252) - 1237884..1238582 (-) 699 WP_126435604.1 glucosaminidase domain-containing protein -
  ELZ47_RS06375 (NCTC10904_01253) yihA 1238730..1239317 (-) 588 WP_126435605.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  ELZ47_RS06380 (NCTC10904_01254) clpX 1239328..1240557 (-) 1230 WP_002917310.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  ELZ47_RS06385 (NCTC10904_01255) - 1240609..1240779 (-) 171 WP_002895584.1 hypothetical protein -
  ELZ47_RS06390 (NCTC10904_01256) - 1240782..1241294 (-) 513 WP_126435606.1 dihydrofolate reductase -
  ELZ47_RS06395 (NCTC10904_01257) - 1241419..1242258 (-) 840 WP_002915301.1 thymidylate synthase -
  ELZ47_RS06400 (NCTC10904_01258) - 1242363..1243322 (-) 960 WP_126435607.1 ROK family glucokinase -
  ELZ47_RS06405 (NCTC10904_01259) - 1244077..1244487 (-) 411 WP_002933857.1 GNAT family N-acetyltransferase -
  ELZ47_RS06410 (NCTC10904_01260) - 1244559..1245146 (-) 588 WP_126435608.1 hypothetical protein -

Sequence

Protein


Download         Length: 409 a.a.        Molecular weight: 45587.02 Da        Isoelectric Point: 4.3984

>NTDB_id=1117818 ELZ47_RS06380 WP_002917310.1 1239328..1240557(-) (clpX) [Streptococcus sanguinis strain NCTC 10904]
MPTSRNDDMMVFCSFCGKNQDEVQKIIAGNNAFICNECVELAQEIIREELAEEVLADLSEVPKPQELLNILNHYVIGQDR
AKRALAVAVYNHYKRINYHDSREEEDVELQKSNILMIGPTGSGKTFLAQTLARSLNVPFAIADATALTEAGYVGEDVENI
LLKLLQAADFNIERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDTK
NILFIVGGAFDGIEEIVKQRLGEKIIGFGQNNRAIDEDGSYMQEIISEDVQKFGIIPELIGRLPVFAALEQLTVDDLVRI
LKEPRNALIKQYQALLSYDDVKLEFDEDALQEIANKAIERKTGARGLRSIIEETMMDVMFEVPSQENVKLVRITKEAVDG
TDKPILETA

Nucleotide


Download         Length: 1230 bp        

>NTDB_id=1117818 ELZ47_RS06380 WP_002917310.1 1239328..1240557(-) (clpX) [Streptococcus sanguinis strain NCTC 10904]
ATGCCTACAAGTCGTAATGATGATATGATGGTTTTTTGTTCTTTCTGTGGGAAGAACCAAGATGAGGTGCAGAAGATTAT
CGCTGGTAACAATGCCTTTATCTGTAATGAATGTGTGGAACTGGCGCAGGAAATCATCCGTGAAGAGCTAGCTGAGGAAG
TGCTGGCAGATTTGTCTGAGGTGCCAAAACCTCAGGAGCTGCTGAATATCTTGAACCACTATGTTATCGGGCAAGACCGA
GCTAAGCGTGCCTTAGCGGTAGCGGTCTATAATCACTACAAGCGTATTAACTATCACGACAGCCGTGAAGAAGAAGATGT
GGAACTGCAAAAGTCAAATATTTTGATGATTGGTCCGACCGGGTCAGGTAAGACCTTCCTGGCGCAGACTCTGGCTCGCA
GCCTCAATGTGCCTTTCGCCATTGCGGACGCAACAGCTTTGACTGAAGCTGGTTATGTCGGTGAAGATGTGGAAAATATC
CTCCTCAAGCTTTTGCAGGCTGCTGACTTTAATATTGAGCGTGCAGAACGCGGCATTATCTATGTCGATGAGATTGATAA
AATTGCCAAGAAAGGTGAGAATGTCTCAATTACTCGTGATGTTTCGGGTGAAGGAGTTCAGCAAGCTCTCTTGAAGATTA
TCGAAGGAACAGTAGCTAGTGTACCGCCGCAAGGTGGACGCAAGCATCCGCAGCAGGAAATGATTCAGGTTGATACCAAG
AATATTCTCTTCATTGTTGGCGGTGCTTTTGACGGTATCGAAGAAATCGTCAAACAGCGTCTGGGTGAGAAAATCATTGG
TTTCGGTCAGAATAACCGGGCGATTGACGAAGATGGGTCCTATATGCAGGAAATTATCTCAGAAGACGTTCAAAAGTTTG
GAATTATCCCTGAGTTGATTGGTCGTTTGCCTGTTTTTGCTGCTCTGGAGCAACTGACAGTTGATGATTTGGTTCGGATT
TTGAAAGAGCCTAGAAACGCCCTTATTAAGCAGTATCAGGCGCTTCTATCTTATGATGATGTTAAGCTTGAATTTGACGA
AGATGCTTTGCAGGAGATTGCCAATAAAGCGATTGAACGTAAAACCGGTGCACGCGGTCTTAGATCAATCATCGAAGAAA
CTATGATGGATGTCATGTTTGAAGTTCCAAGTCAGGAAAATGTCAAACTTGTCCGCATTACCAAAGAAGCAGTAGATGGA
ACAGACAAGCCTATTCTAGAGACTGCCTAA

Domains

Predicted by InterproScan.

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)

AAA domain (Cdc48 subfamily) (AAA_2)

(110-305)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(312-389)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3R9GT11

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

85.575

100

0.856
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

57.606

98.044

0.565

Multiple sequence alignment