Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   ELZ47_RS02675 Genome accession   NZ_LR134002
Coordinates   533530..534828 (+) Length   432 a.a.
NCBI ID   WP_125331604.1    Uniprot ID   A0AAJ5NGG8
Organism   Streptococcus sanguinis strain NCTC 10904     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 528530..539828
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ELZ47_RS02650 (NCTC10904_00524) - 529271..529903 (+) 633 WP_009659067.1 response regulator transcription factor -
  ELZ47_RS02655 (NCTC10904_00525) - 529943..531343 (+) 1401 WP_125331610.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  ELZ47_RS02660 (NCTC10904_00526) - 531343..531705 (+) 363 WP_002901252.1 S1 RNA-binding domain-containing protein -
  ELZ47_RS02665 (NCTC10904_00527) cysK 531811..532740 (-) 930 WP_125331608.1 cysteine synthase A -
  ELZ47_RS02670 (NCTC10904_00528) - 532836..533474 (-) 639 WP_125331606.1 YigZ family protein -
  ELZ47_RS02675 (NCTC10904_00529) comFA/cflA 533530..534828 (+) 1299 WP_125331604.1 DEAD/DEAH box helicase Machinery gene
  ELZ47_RS02680 (NCTC10904_00530) - 534825..535490 (+) 666 WP_125331602.1 ComF family protein -
  ELZ47_RS02685 (NCTC10904_00531) hpf 535572..536114 (+) 543 WP_002903257.1 ribosome hibernation-promoting factor, HPF/YfiA family -

Sequence

Protein


Download         Length: 432 a.a.        Molecular weight: 49424.11 Da        Isoelectric Point: 8.2837

>NTDB_id=1117808 ELZ47_RS02675 WP_125331604.1 533530..534828(+) (comFA/cflA) [Streptococcus sanguinis strain NCTC 10904]
MLELQDCLGRIFTESQLESSLRAQAKAIPSIQEEKGKLRCGRCNSLIERENQLPVGAYYCRECLILGRVRSDQKLYYFPQ
EDFPKNQVLKWRGQLTEFQGKVSKGLLDALEKRQDTLVHAVTGAGKTEMIYQVLARVIDRGGSVCLASPRIDVCLELYRR
LKEDFSCEIALLHGESEAYFRSPLVIATTHQLLKFYQAFDLLIVDEVDAFPYVDNPMLYHAVERSVKEDATTIFLTATST
DELDKRVQKGELKRLSLPRRFHGNPLTIPQKVWLSDFQKHLQKKKIAPKLLNYIQKQRETQFPLLIFAAEIQRGEDFAQA
LQIALPDEKLAFVASTTENRLEIVEQFRRKEITILVTTTILERGVTFPGVDVFVLEANHRLFSRSALVQISGRVGRSLDR
PTGQLLFFHDGTTLAMEKAIREMRDMNKEAGL

Nucleotide


Download         Length: 1299 bp        

>NTDB_id=1117808 ELZ47_RS02675 WP_125331604.1 533530..534828(+) (comFA/cflA) [Streptococcus sanguinis strain NCTC 10904]
ATGTTAGAGTTACAAGATTGTTTAGGACGGATATTTACAGAAAGTCAGTTAGAGTCTAGCTTGCGCGCACAAGCAAAAGC
AATTCCCAGTATCCAAGAAGAAAAAGGCAAGCTACGCTGCGGACGCTGCAACAGTTTGATTGAACGAGAAAATCAGCTAC
CTGTTGGAGCTTATTATTGTAGAGAATGCTTAATCTTGGGACGGGTGCGGAGTGACCAAAAACTCTACTATTTTCCTCAA
GAGGATTTTCCTAAAAATCAGGTGCTTAAATGGCGGGGGCAACTGACAGAGTTTCAGGGGAAGGTCTCCAAAGGCTTACT
TGATGCGCTAGAGAAAAGACAGGATACGTTAGTGCATGCTGTTACTGGCGCTGGAAAAACAGAAATGATTTACCAAGTGC
TTGCCAGAGTTATTGACAGAGGTGGTTCTGTTTGCTTGGCCAGTCCGCGGATTGATGTTTGTTTAGAGCTTTATCGGCGC
CTTAAAGAAGATTTTTCTTGTGAAATAGCCCTTCTGCATGGGGAGTCAGAAGCTTATTTTCGCAGTCCCTTGGTAATTGC
TACCACTCACCAGCTATTAAAATTTTATCAAGCTTTTGATTTGCTGATTGTTGATGAGGTAGACGCCTTTCCTTATGTGG
ATAATCCCATGCTGTATCACGCTGTAGAACGTTCTGTGAAAGAGGATGCTACAACTATTTTTCTGACAGCCACTTCCACG
GATGAACTGGATAAAAGGGTTCAAAAAGGTGAGCTGAAACGCCTGAGTCTTCCCAGAAGATTTCATGGTAATCCCTTGAC
TATCCCTCAGAAAGTTTGGTTATCCGATTTTCAAAAACATCTTCAGAAGAAGAAAATAGCACCTAAACTTTTGAACTATA
TACAAAAACAGAGGGAGACTCAATTTCCTCTCTTGATATTTGCTGCAGAAATTCAAAGAGGAGAGGATTTTGCTCAGGCT
CTGCAGATTGCTCTGCCGGATGAAAAGCTAGCTTTTGTTGCCTCCACAACAGAAAATCGTCTGGAGATTGTTGAACAGTT
TCGTCGCAAGGAGATCACTATTTTGGTGACAACGACTATCTTAGAGCGTGGGGTAACCTTTCCTGGTGTAGATGTTTTTG
TCTTGGAAGCCAATCATCGCTTGTTCAGTCGTAGTGCCCTGGTTCAGATTTCAGGCCGAGTTGGCCGCAGTTTGGACAGA
CCAACTGGACAGTTGCTATTTTTTCATGATGGGACTACCCTTGCTATGGAAAAGGCAATTCGGGAAATGAGGGATATGAA
TAAGGAGGCGGGATTATGA

Domains

Predicted by InterproScan.

DEAD/DEAH box helicase (DEAD)

(109-244)

Helicase conserved C-terminal domain (Helicase_C)

(290-396)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

70.96

98.843

0.701
  comFA/cflA Streptococcus pneumoniae D39

70.96

98.843

0.701
  comFA/cflA Streptococcus pneumoniae R6

70.96

98.843

0.701
  comFA/cflA Streptococcus pneumoniae TIGR4

70.726

98.843

0.699
  comFA/cflA Streptococcus mitis NCTC 12261

70.824

98.38

0.697
  comFA/cflA Streptococcus mitis SK321

69.647

98.38

0.685
  comFA Lactococcus lactis subsp. cremoris KW2

55.025

92.13

0.507
  comFA Latilactobacillus sakei subsp. sakei 23K

38.462

99.306

0.382

Multiple sequence alignment