Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA   Type   Machinery gene
Locus tag   ELZ45_RS07730 Genome accession   NZ_LR133917
Coordinates   1551736..1552710 (-) Length   324 a.a.
NCBI ID   WP_000697235.1    Uniprot ID   A0AB74Q180
Organism   Staphylococcus aureus strain NCTC8317     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1546736..1557710
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ELZ45_RS07690 (NCTC8317_01442) gcvT 1547237..1548328 (-) 1092 WP_000093349.1 glycine cleavage system aminomethyltransferase GcvT -
  ELZ45_RS07695 - 1548487..1549011 (-) 525 WP_001015121.1 shikimate kinase -
  ELZ45_RS07700 - 1549001..1549147 (-) 147 WP_001789879.1 hypothetical protein -
  ELZ45_RS07705 (NCTC8317_01444) comGF 1549244..1549741 (-) 498 WP_029694076.1 competence type IV pilus minor pilin ComGF Machinery gene
  ELZ45_RS07710 (NCTC8317_01445) comGE 1549659..1549958 (-) 300 WP_000844413.1 hypothetical protein Machinery gene
  ELZ45_RS07715 (NCTC8317_01446) comGD 1549945..1550391 (-) 447 WP_072433556.1 competence type IV pilus minor pilin ComGD Machinery gene
  ELZ45_RS07720 (NCTC8317_01447) comGC 1550369..1550680 (-) 312 WP_000472256.1 competence type IV pilus major pilin ComGC Machinery gene
  ELZ45_RS07725 (NCTC8317_01448) comGB 1550694..1551764 (-) 1071 WP_000776422.1 competence type IV pilus assembly protein ComGB Machinery gene
  ELZ45_RS07730 (NCTC8317_01449) comGA 1551736..1552710 (-) 975 WP_000697235.1 competence type IV pilus ATPase ComGA Machinery gene
  ELZ45_RS07735 (NCTC8317_01450) - 1552762..1553385 (-) 624 WP_001223008.1 MBL fold metallo-hydrolase -
  ELZ45_RS07740 (NCTC8317_01451) - 1553382..1553711 (-) 330 WP_001018871.1 MTH1187 family thiamine-binding protein -
  ELZ45_RS07745 (NCTC8317_01452) - 1553711..1554697 (-) 987 WP_000161315.1 ROK family glucokinase -
  ELZ45_RS07750 - 1554694..1554897 (-) 204 WP_000087561.1 YqgQ family protein -
  ELZ45_RS07755 (NCTC8317_01453) - 1554878..1556341 (-) 1464 WP_001017867.1 rhomboid family intramembrane serine protease -
  ELZ45_RS07760 (NCTC8317_01454) - 1556353..1556892 (-) 540 WP_000164544.1 5-formyltetrahydrofolate cyclo-ligase -
  ELZ45_RS07765 (NCTC8317_01455) rpmG 1557101..1557250 (-) 150 WP_001265709.1 50S ribosomal protein L33 -

Sequence

Protein


Download         Length: 324 a.a.        Molecular weight: 36883.93 Da        Isoelectric Point: 8.8516

>NTDB_id=1117641 ELZ45_RS07730 WP_000697235.1 1551736..1552710(-) (comGA) [Staphylococcus aureus strain NCTC8317]
MKILFQEVINKAIEMKASDVHFIPVKNEVSIKFRINDNLEQYEQIGNSIYQKLLVYMKFQAGLDVSTQQVAQSGRYSYHF
NKIYFLRISTLPLSLGQESCVIRIVPQFFQQQKSTYKFNDFKHLMNKKQGLLLFSGPTGSGKSTLMYQMVSYANKALNLN
VISIEDPVEMQIPGIVQINVNDKAGINYVNSFKAILRCDPDVILIGEIRDKDVAKCVIQASLSGHLVLTTLHATDCKGAI
LRLLEMGISVQELIQATNLIINQRLVTTIKQQRQLVCEILSQQQLRYFFSHNHSLPSSFKNLEDKLDDMTKAGVICETTM
DKYI

Nucleotide


Download         Length: 975 bp        

>NTDB_id=1117641 ELZ45_RS07730 WP_000697235.1 1551736..1552710(-) (comGA) [Staphylococcus aureus strain NCTC8317]
TTGAAGATTCTATTTCAAGAAGTAATTAATAAAGCGATAGAAATGAAAGCGAGTGATGTACATTTTATTCCAGTTAAAAA
TGAAGTAAGTATTAAATTTAGAATTAATGATAACTTGGAGCAGTATGAACAAATTGGGAATAGCATTTATCAAAAGTTAT
TAGTTTATATGAAGTTTCAAGCTGGGCTTGATGTTTCTACACAGCAAGTCGCACAGAGCGGTCGATATAGTTACCATTTC
AATAAAATATATTTTTTGAGAATATCAACTTTACCATTGTCACTTGGCCAAGAAAGTTGTGTTATCAGAATTGTACCTCA
ATTTTTTCAACAACAGAAATCAACTTATAAATTCAATGATTTTAAACACCTCATGAATAAGAAACAAGGATTACTATTGT
TTAGTGGGCCAACTGGTTCAGGTAAGAGTACATTAATGTATCAAATGGTCTCATACGCGAATAAAGCCTTGAATTTAAAT
GTAATTTCTATAGAGGATCCTGTAGAGATGCAAATTCCTGGTATCGTCCAAATTAATGTGAATGATAAAGCTGGCATTAA
CTATGTAAATTCGTTTAAAGCTATTTTAAGATGTGATCCTGATGTTATTTTAATAGGTGAAATCAGAGATAAAGATGTTG
CCAAGTGTGTTATACAGGCTAGTTTAAGTGGTCACCTTGTTCTGACTACATTGCATGCAACTGATTGTAAAGGTGCTATT
TTAAGGCTATTAGAAATGGGCATTTCTGTACAAGAATTGATACAGGCAACTAACTTAATTATAAACCAACGACTTGTAAC
TACTATTAAGCAACAGCGACAATTAGTATGTGAAATTCTATCTCAGCAACAACTCCGATATTTCTTTTCCCATAATCATT
CATTACCATCATCATTTAAGAACTTAGAAGATAAACTTGATGATATGACAAAAGCAGGTGTCATTTGTGAAACTACAATG
GATAAATACATTTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(8-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA Staphylococcus aureus MW2

99.691

100

0.997
  comGA Staphylococcus aureus N315

99.691

100

0.997

Multiple sequence alignment