Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   EW033_RS03400 Genome accession   NZ_LR130515
Coordinates   654965..655534 (+) Length   189 a.a.
NCBI ID   WP_000872873.1    Uniprot ID   -
Organism   Staphylococcus aureus strain BPH2947 isolate BPH2947     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 649965..660534
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EW033_RS03375 cysE 651178..651825 (+) 648 WP_001838365.1 serine O-acetyltransferase -
  EW033_RS03380 cysS 651809..653209 (+) 1401 WP_000631964.1 cysteine--tRNA ligase -
  EW033_RS03385 - 653202..653606 (+) 405 WP_000370182.1 Mini-ribonuclease 3 -
  EW033_RS03390 rlmB 653614..654360 (+) 747 WP_000390328.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  EW033_RS03395 - 654360..654884 (+) 525 WP_000664738.1 NYN domain-containing protein -
  EW033_RS03400 sigH 654965..655534 (+) 570 WP_000872873.1 sigma-70 family RNA polymerase sigma factor Regulator
  EW033_RS03405 rpmG 655649..655792 (+) 144 WP_001788193.1 50S ribosomal protein L33 -
  EW033_RS03410 secE 655848..656030 (+) 183 WP_001074474.1 preprotein translocase subunit SecE -
  EW033_RS03415 nusG 656043..656591 (+) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  EW033_RS03420 rplK 656772..657194 (+) 423 WP_001085792.1 50S ribosomal protein L11 -
  EW033_RS03425 rplA 657402..658094 (+) 693 WP_001074619.1 50S ribosomal protein L1 -
  EW033_RS03435 rplJ 658366..658866 (+) 501 WP_001273085.1 50S ribosomal protein L10 -
  EW033_RS03440 rplL 658909..659277 (+) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  EW033_RS03445 - 659452..660060 (+) 609 WP_031892351.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23028.91 Da        Isoelectric Point: 9.4170

>NTDB_id=1116892 EW033_RS03400 WP_000872873.1 654965..655534(+) (sigH) [Staphylococcus aureus strain BPH2947 isolate BPH2947]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRFDVENNYLNKLAIKELICQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=1116892 EW033_RS03400 WP_000872873.1 654965..655534(+) (sigH) [Staphylococcus aureus strain BPH2947 isolate BPH2947]
TTGAAATACGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTTTGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTTGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAATTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus N315

99.471

100

0.995
  sigH Staphylococcus aureus MW2

98.413

100

0.984

Multiple sequence alignment