Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   EW030_RS07850 Genome accession   NZ_LR130511
Coordinates   1579215..1579901 (-) Length   228 a.a.
NCBI ID   WP_001802022.1    Uniprot ID   A0A7U7EYP5
Organism   Staphylococcus aureus strain BPH2819 isolate BPH2819     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1574215..1584901
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EW030_RS07830 rpsT 1575129..1575380 (+) 252 WP_001274017.1 30S ribosomal protein S20 -
  EW030_RS07835 holA 1575425..1576399 (-) 975 WP_001282563.1 DNA polymerase III subunit delta -
  EW030_RS07840 comEC 1576456..1578657 (-) 2202 WP_061394002.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  EW030_RS07845 - 1578662..1579123 (-) 462 WP_000439693.1 ComE operon protein 2 -
  EW030_RS07850 comEA 1579215..1579901 (-) 687 WP_001802022.1 ComEA family DNA-binding protein Machinery gene
  EW030_RS07855 - 1579941..1580657 (-) 717 WP_000084830.1 class I SAM-dependent DNA methyltransferase -
  EW030_RS07860 rsfS 1580660..1581013 (-) 354 WP_001088020.1 ribosome silencing factor -
  EW030_RS07865 yqeK 1581014..1581598 (-) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  EW030_RS07870 nadD 1581588..1582157 (-) 570 WP_000725167.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  EW030_RS07875 yhbY 1582160..1582450 (-) 291 WP_000955235.1 ribosome assembly RNA-binding protein YhbY -
  EW030_RS07880 aroE 1582454..1583260 (-) 807 WP_000666757.1 shikimate dehydrogenase -
  EW030_RS07885 yqeH 1583274..1584374 (-) 1101 WP_001280137.1 ribosome biogenesis GTPase YqeH -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25900.65 Da        Isoelectric Point: 9.6751

>NTDB_id=1116824 EW030_RS07850 WP_001802022.1 1579215..1579901(-) (comEA) [Staphylococcus aureus strain BPH2819 isolate BPH2819]
MVLLYQFLLRYKDFLTQWKLYIISAVVLIMVLIGFIFWRQDDYTSRNFENKDTALKQSTSENNSLSKLEDVQVKDGDNSK
NKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLDDADVSRINLSEKLTDQKMIFIPHKGQKNVEPQIEVNSVHVKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTI

Nucleotide


Download         Length: 687 bp        

>NTDB_id=1116824 EW030_RS07850 WP_001802022.1 1579215..1579901(-) (comEA) [Staphylococcus aureus strain BPH2819 isolate BPH2819]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAGTGGAAGTTATATATTATAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAAATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAAATAATAGTTTGTCCAAATTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAAGGTCCTGTATATGTCGATGTAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTGGATGATGCAGATGTAAGTCGAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATACCTCATAAAGGACAAAAGAATGTTGAACCACAAATTGAAGTAAACAGTGTGCACGTAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACCGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTAGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGATATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7EYP5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus N315

100

100

1
  comEA Staphylococcus aureus MW2

97.368

100

0.974

Multiple sequence alignment