Detailed information    

insolico Bioinformatically predicted

Overview

Name   coiA   Type   Machinery gene
Locus tag   EW030_RS04660 Genome accession   NZ_LR130511
Coordinates   927694..928680 (+) Length   328 a.a.
NCBI ID   WP_000959282.1    Uniprot ID   A0A7U7EXT8
Organism   Staphylococcus aureus strain BPH2819 isolate BPH2819     
Function   require for natural transformation (predicted from homology)   
Unclear

Genomic Context

Location: 922694..933680
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EW030_RS04635 opp4B 922908..923870 (+) 963 WP_000915997.1 oligopeptide ABC transporter permease -
  EW030_RS04640 opp4C 923882..924763 (+) 882 WP_001180280.1 oligopeptide ABC transporter permease -
  EW030_RS04645 trpS 924805..925794 (-) 990 WP_000448934.1 tryptophan--tRNA ligase -
  EW030_RS04650 spxA 926088..926483 (+) 396 WP_000258003.1 transcriptional regulator SpxA -
  EW030_RS04655 mecA 926854..927573 (+) 720 WP_001217728.1 adaptor protein MecA -
  EW030_RS04660 coiA 927694..928680 (+) 987 WP_000959282.1 competence protein CoiA Machinery gene
  EW030_RS04665 pepF 928728..930536 (+) 1809 WP_000082725.1 oligoendopeptidase F -
  EW030_RS04670 yjbH 930996..931802 (-) 807 WP_000896697.1 protease adaptor protein YjbH -
  EW030_RS04675 - 931825..932190 (-) 366 WP_000214070.1 truncated hemoglobin YjbI -
  EW030_RS04680 - 932294..932887 (-) 594 WP_000224619.1 CYTH domain-containing protein -
  EW030_RS04685 - 933073..933420 (+) 348 WP_001242103.1 hypothetical protein -

Sequence

Protein


Download         Length: 328 a.a.        Molecular weight: 38878.55 Da        Isoelectric Point: 9.5714

>NTDB_id=1116809 EW030_RS04660 WP_000959282.1 927694..928680(+) (coiA) [Staphylococcus aureus strain BPH2819 isolate BPH2819]
MLVALNEEKERVLATTALRKTQYFCPVCGKQVILKRGLKVISHFAHKHLAEQKCFNNETIKHYKSKLILAQMIQQQGCKV
EIEPFLKEIKQIPDILINNKYVIELQYSPIPYKQILQRTEGLKKMGYKVSWLLNDVDYCHNKVKFNHFHSLFINPITRKL
HTFNLEKKQIMMFQQIQYLGGHKYVAEKRNAKIIELFNEAPCDYHAVYKLSKFAINQYIKYCRWQNSVLEPTLSAMYQLQ
LTDQEVVYNYGYIFPEQIYIENHPIEWQLQVDLWLKNGKSKLVNDNLNYFKLKKFIVALESKTAIIEKLINNYLNICSDR
GNDVQILF

Nucleotide


Download         Length: 987 bp        

>NTDB_id=1116809 EW030_RS04660 WP_000959282.1 927694..928680(+) (coiA) [Staphylococcus aureus strain BPH2819 isolate BPH2819]
ATGTTAGTAGCTTTAAATGAAGAAAAGGAACGTGTGTTAGCAACTACTGCATTGAGAAAGACACAATATTTTTGTCCTGT
GTGTGGCAAGCAAGTTATTTTAAAGCGTGGGCTCAAAGTAATTAGTCATTTTGCACATAAACATTTAGCGGAACAAAAAT
GTTTTAATAATGAAACGATTAAACATTATAAAAGTAAATTGATTTTAGCACAGATGATACAGCAACAAGGATGTAAAGTA
GAGATAGAGCCATTTTTAAAAGAAATAAAACAAATTCCGGATATTTTGATTAATAATAAATATGTTATTGAGCTACAGTA
TTCGCCAATTCCTTATAAACAGATTCTTCAACGAACGGAAGGTTTAAAGAAAATGGGATATAAAGTAAGTTGGTTATTAA
ATGATGTTGATTATTGTCATAATAAAGTGAAGTTCAATCATTTTCATAGTTTGTTTATTAATCCAATCACTCGAAAACTT
CATACGTTCAATTTAGAGAAAAAACAAATAATGATGTTTCAACAAATACAATATTTAGGCGGGCACAAATATGTCGCTGA
AAAAAGGAATGCCAAAATTATTGAGTTGTTTAATGAGGCGCCTTGTGATTATCATGCTGTTTATAAATTATCAAAGTTCG
CAATTAATCAATATATCAAATATTGTCGCTGGCAAAATTCTGTTTTAGAACCCACTTTAAGTGCAATGTATCAATTACAG
TTAACTGATCAAGAAGTAGTGTACAATTATGGTTATATTTTTCCAGAGCAAATTTATATTGAAAATCATCCAATTGAGTG
GCAATTACAAGTTGATTTATGGTTAAAGAATGGAAAAAGCAAATTAGTAAATGACAATCTTAATTATTTTAAACTGAAAA
AATTTATTGTTGCTCTAGAAAGTAAAACAGCAATTATAGAAAAACTTATTAACAATTATTTAAATATTTGTTCAGATAGA
GGTAATGACGTGCAAATTTTGTTCTAA

Domains

Predicted by InterproScan.

Competence protein CoiA-like family (CoiA_nuc)

(6-308)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7EXT8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  coiA Staphylococcus aureus N315

100

100

1
  coiA Staphylococcus aureus MW2

97.561

100

0.976

Multiple sequence alignment