Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   EW030_RS02560 Genome accession   NZ_LR130511
Coordinates   524500..525069 (+) Length   189 a.a.
NCBI ID   WP_000872882.1    Uniprot ID   A0A7U7EXA1
Organism   Staphylococcus aureus strain BPH2819 isolate BPH2819     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 519500..530069
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EW030_RS02535 cysE 520713..521360 (+) 648 WP_001805237.1 serine O-acetyltransferase -
  EW030_RS02540 cysS 521344..522744 (+) 1401 WP_000631969.1 cysteine--tRNA ligase -
  EW030_RS02545 - 522737..523141 (+) 405 WP_000370182.1 Mini-ribonuclease 3 -
  EW030_RS02550 rlmB 523149..523895 (+) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  EW030_RS02555 - 523895..524419 (+) 525 WP_000664737.1 NYN domain-containing protein -
  EW030_RS02560 sigH 524500..525069 (+) 570 WP_000872882.1 sigma-70 family RNA polymerase sigma factor Regulator
  EW030_RS02565 rpmG 525184..525327 (+) 144 WP_001788193.1 50S ribosomal protein L33 -
  EW030_RS02570 secE 525383..525565 (+) 183 WP_129622209.1 preprotein translocase subunit SecE -
  EW030_RS02575 nusG 525578..526126 (+) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  EW030_RS02580 rplK 526307..526729 (+) 423 WP_001085792.1 50S ribosomal protein L11 -
  EW030_RS02585 rplA 526937..527629 (+) 693 WP_001074619.1 50S ribosomal protein L1 -
  EW030_RS02595 rplJ 527901..528401 (+) 501 WP_001273085.1 50S ribosomal protein L10 -
  EW030_RS02600 rplL 528444..528812 (+) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  EW030_RS02605 - 528987..529595 (+) 609 WP_000020304.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23044.91 Da        Isoelectric Point: 9.4170

>NTDB_id=1116804 EW030_RS02560 WP_000872882.1 524500..525069(+) (sigH) [Staphylococcus aureus strain BPH2819 isolate BPH2819]
MKYDLTTQDSTIKRNNSINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRFDVENNYLNKLAIKELICQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=1116804 EW030_RS02560 WP_000872882.1 524500..525069(+) (sigH) [Staphylococcus aureus strain BPH2819 isolate BPH2819]
TTGAAATATGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATTCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTTTGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTTGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAATTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7EXA1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus N315

100

100

1
  sigH Staphylococcus aureus MW2

97.884

100

0.979

Multiple sequence alignment