Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   EW032_RS07985 Genome accession   NZ_LR130509
Coordinates   1602039..1602725 (-) Length   228 a.a.
NCBI ID   WP_001793467.1    Uniprot ID   A0A641AAY3
Organism   Staphylococcus aureus strain BPH2760 isolate BPH2760     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1597039..1607725
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EW032_RS07965 rpsT 1597953..1598204 (+) 252 WP_001274017.1 30S ribosomal protein S20 -
  EW032_RS07970 holA 1598249..1599223 (-) 975 WP_001282568.1 DNA polymerase III subunit delta -
  EW032_RS07975 comEC 1599280..1601481 (-) 2202 WP_001566670.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  EW032_RS07980 - 1601486..1601947 (-) 462 WP_000439693.1 ComE operon protein 2 -
  EW032_RS07985 comEA 1602039..1602725 (-) 687 WP_001793467.1 ComEA family DNA-binding protein Machinery gene
  EW032_RS07990 - 1602765..1603481 (-) 717 WP_000084829.1 class I SAM-dependent DNA methyltransferase -
  EW032_RS07995 rsfS 1603484..1603837 (-) 354 WP_001088022.1 ribosome silencing factor -
  EW032_RS08000 yqeK 1603838..1604422 (-) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  EW032_RS08005 nadD 1604412..1604981 (-) 570 WP_000725167.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  EW032_RS08010 yhbY 1604984..1605274 (-) 291 WP_000955235.1 ribosome assembly RNA-binding protein YhbY -
  EW032_RS08015 aroE 1605278..1606084 (-) 807 WP_000666748.1 shikimate dehydrogenase -
  EW032_RS08020 yqeH 1606098..1607198 (-) 1101 WP_001280141.1 ribosome biogenesis GTPase YqeH -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25786.50 Da        Isoelectric Point: 9.6753

>NTDB_id=1116783 EW032_RS07985 WP_001793467.1 1602039..1602725(-) (comEA) [Staphylococcus aureus strain BPH2760 isolate BPH2760]
MVLLYQFLLRYKDFLTQWKLYIISAVVLIMVLIGFIFWRQDDYTSRNFENKDNALKQSTSENSSLSKVEDVQVKDGDNSK
NKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLEDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQIGVNSVHVKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTI

Nucleotide


Download         Length: 687 bp        

>NTDB_id=1116783 EW032_RS07985 WP_001793467.1 1602039..1602725(-) (comEA) [Staphylococcus aureus strain BPH2760 isolate BPH2760]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAATGGAAGTTATATATTATAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAAATTTTGAAAATAAAGATAATG
CTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAAGTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAGGGTCCTGTATATGTCGATGTAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTGGAGGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATACCTCATAAAGGACAAAAGAATGTTGAACCACAAATTGGAGTAAACAGTGTGCATGTAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACCGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTAGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGATATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A641AAY3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus MW2

100

100

1
  comEA Staphylococcus aureus N315

97.368

100

0.974

Multiple sequence alignment