Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   EW032_RS02800 Genome accession   NZ_LR130509
Coordinates   555747..556316 (+) Length   189 a.a.
NCBI ID   WP_000872877.1    Uniprot ID   A0A641A2F3
Organism   Staphylococcus aureus strain BPH2760 isolate BPH2760     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 550747..561316
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EW032_RS02775 cysE 551960..552607 (+) 648 WP_001805237.1 serine O-acetyltransferase -
  EW032_RS02780 cysS 552591..553991 (+) 1401 WP_000631973.1 cysteine--tRNA ligase -
  EW032_RS02785 - 553984..554388 (+) 405 WP_000370182.1 Mini-ribonuclease 3 -
  EW032_RS02790 rlmB 554396..555142 (+) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  EW032_RS02795 - 555142..555666 (+) 525 WP_000664738.1 NYN domain-containing protein -
  EW032_RS02800 sigH 555747..556316 (+) 570 WP_000872877.1 sigma-70 family RNA polymerase sigma factor Regulator
  EW032_RS02805 rpmG 556431..556574 (+) 144 WP_001788193.1 50S ribosomal protein L33 -
  EW032_RS02810 secE 556630..556812 (+) 183 WP_001074473.1 preprotein translocase subunit SecE -
  EW032_RS02815 nusG 556825..557373 (+) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  EW032_RS02820 rplK 557554..557976 (+) 423 WP_001085792.1 50S ribosomal protein L11 -
  EW032_RS02825 rplA 558184..558876 (+) 693 WP_063456263.1 50S ribosomal protein L1 -
  EW032_RS02835 rplJ 559148..559648 (+) 501 WP_001273087.1 50S ribosomal protein L10 -
  EW032_RS02840 rplL 559691..560059 (+) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  EW032_RS02845 - 560234..560842 (+) 609 WP_000020302.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23126.01 Da        Isoelectric Point: 9.6015

>NTDB_id=1116763 EW032_RS02800 WP_000872877.1 555747..556316(+) (sigH) [Staphylococcus aureus strain BPH2760 isolate BPH2760]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRYDVENNYLNKLAIKELIRQFKYLSVFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=1116763 EW032_RS02800 WP_000872877.1 555747..556316(+) (sigH) [Staphylococcus aureus strain BPH2760 isolate BPH2760]
TTGAAATACGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTATGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTCGTCAGTTTAAGTATTTGAGTGTATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAACTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A641A2F3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus MW2

100

100

1
  sigH Staphylococcus aureus N315

97.884

100

0.979

Multiple sequence alignment