Detailed information NTG1116666

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: EW023_RS01490
• Genome accession: NZ_LR130239
• Coordinates: 274087..275157 (+)
• Length: 356 a.a.
• NCBI ID: WP_023612409.1
• Uniprot ID: A0A5S4TIQ7
• Organism: Streptococcus pyogenes strain PS003 isolate PS003
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 269087..280157

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EW023_RS01475	amiA	269606..271585 (+)	1980	WP_023612402.1	peptide ABC transporter substrate-binding protein	Regulator
EW023_RS01480	amiC	271650..273152 (+)	1503	WP_011017334.1	ABC transporter permease	Regulator
EW023_RS01485	amiD	273152..274078 (+)	927	WP_023612408.1	oligopeptide ABC transporter permease OppC	Regulator
EW023_RS01490	amiE	274087..275157 (+)	1071	WP_023612409.1	ABC transporter ATP-binding protein	Regulator
EW023_RS01495	amiF	275150..276073 (+)	924	WP_023612424.1	ABC transporter ATP-binding protein	Regulator
EW023_RS10015	-	276111..276200 (-)	90	WP_110002794.1	IS3 family transposase	-
EW023_RS01505	-	276221..276400 (-)	180	WP_023612403.1	hypothetical protein	-

Sequence

Protein

• Length: 356 a.a.
• Molecular weight: 39689.75 Da
• Isoelectric Point: 5.6686

>NTDB_id=1116666 EW023_RS01490 WP_023612409.1 274087..275157(+) (amiE) [Streptococcus pyogenes strain PS003 isolate PS003]
MTKENNVILTAKDVVVEFDVRDRVLTAIRNVSLELVEGEVLAFVGESGSGKSVLTKTFTGMLESNGRIANGSIVYRGQEL
TDLKTNKEWAKIRGSKIATIFQDPMTSLSPIKTIGSQITEVIIKHQKVSHAKAKEMALDYMNKVGIPNAKKRFEDYPFEY
SGGMRQRIVIAIALACRPDILICDEPTTALDVTIQAQIVELLKSLQREYHFTIIFITHDLGVVASIADKVAVMYAGEIVE
FGTVEEIFYDPRHPYTWSLLSSLPQLADDSGELYAIPGTPPSLYSPIIGDAFALRSEYAMVLDFEKAPPAINVSETHWAK
TWLLHPEAPKVQKPEVIQDLHQKILRKMSQQEEGNV

Nucleotide

• Length: 1071 bp

>NTDB_id=1116666 EW023_RS01490 WP_023612409.1 274087..275157(+) (amiE) [Streptococcus pyogenes strain PS003 isolate PS003]
ATGACAAAAGAAAATAATGTAATCTTAACTGCCAAAGATGTGGTGGTAGAATTTGATGTGCGTGATCGTGTTTTAACAGC
TATCCGTAACGTCTCACTGGAACTTGTTGAAGGAGAAGTCCTTGCTTTTGTAGGGGAATCAGGCTCAGGTAAATCTGTTT
TAACAAAGACCTTTACAGGGATGTTGGAGTCTAATGGACGCATTGCTAATGGTTCAATTGTCTATCGTGGGCAAGAATTG
ACAGATTTAAAAACAAATAAAGAGTGGGCAAAGATTCGCGGCTCAAAAATCGCAACGATTTTCCAAGACCCAATGACCAG
TCTTAGTCCCATTAAAACTATCGGTAGCCAAATCACAGAAGTGATTATTAAGCACCAAAAAGTAAGTCATGCCAAAGCTA
AAGAAATGGCCCTTGATTACATGAATAAAGTGGGTATCCCAAATGCCAAAAAACGCTTTGAAGATTACCCATTTGAGTAT
TCAGGAGGAATGCGTCAACGTATTGTTATCGCTATTGCTTTAGCTTGTCGCCCAGATATTCTTATCTGTGATGAGCCAAC
AACAGCCCTTGATGTGACTATTCAAGCTCAAATCGTTGAGTTATTGAAGTCGCTTCAACGAGAATATCATTTCACCATTA
TCTTTATTACGCACGATTTAGGTGTTGTGGCAAGCATTGCAGATAAAGTGGCTGTCATGTATGCAGGAGAAATTGTTGAA
TTTGGAACAGTCGAAGAGATTTTCTATGATCCAAGACACCCCTATACATGGAGTTTGCTGTCTAGCTTACCGCAGTTGGC
AGATGATTCTGGTGAACTTTACGCTATTCCAGGAACGCCTCCATCACTTTATTCACCAATTATCGGAGATGCCTTTGCAC
TTCGCTCAGAATATGCTATGGTTTTAGACTTTGAAAAAGCACCTCCGGCGATTAACGTATCTGAGACTCATTGGGCCAAA
ACATGGCTTTTACACCCAGAGGCTCCAAAAGTTCAAAAACCAGAAGTCATTCAAGATTTGCATCAAAAAATCTTAAGGAA
AATGTCACAACAGGAGGAAGGAAATGTCTGA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (29-187)

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-299)

3D structure

• AlphaFold DB: A0A5S4TIQ7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	76.944	100	0.778
amiE	Streptococcus thermophilus LMG 18311	75.833	100	0.767
amiE	Streptococcus thermophilus LMD-9	75.833	100	0.767
oppD	Streptococcus mutans UA159	56.677	94.663	0.537