Detailed information    

insolico Bioinformatically predicted

Overview


Name   comS   Type   Regulator
Locus tag   EW025_RS10500 Genome accession   NZ_LR130238
Coordinates   54088..54183 (+) Length   31 a.a.
NCBI ID   WP_198462994.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain HKU419 isolate HKU419     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context


Location: 49088..59183
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EW025_RS00320 - 50008..51651 (+) 1644 WP_010921779.1 AIPR family protein -
  EW025_RS00325 purB 51669..52961 (+) 1293 WP_010921780.1 adenylosuccinate lyase -
  EW025_RS00330 comR 53093..54004 (+) 912 WP_002986681.1 transcriptional regulator Rgg4/ComR Regulator
  EW025_RS10500 comS 54088..54183 (+) 96 WP_198462994.1 quorum-sensing system DWW-type pheromone Regulator
  EW025_RS00335 ruvB 54230..55228 (+) 999 WP_002986679.1 Holliday junction branch migration DNA helicase RuvB -
  EW025_RS00340 - 55366..55803 (+) 438 WP_002994668.1 low molecular weight protein-tyrosine-phosphatase -
  EW025_RS00345 - 55826..56227 (+) 402 WP_010921781.1 MORN repeat-containing protein -
  EW025_RS00350 - 56224..57999 (+) 1776 WP_010921782.1 acyltransferase family protein -

Sequence


Protein


Download         Length: 31 a.a.        Molecular weight: 3857.66 Da        Isoelectric Point: 10.0436

>NTDB_id=1116648 EW025_RS10500 WP_198462994.1 54088..54183(+) (comS) [Streptococcus pyogenes strain HKU419 isolate HKU419]
MLKKYKYYFIFAALLSFKVVQELSAVDWWRL

Nucleotide


Download         Length: 96 bp        

>NTDB_id=1116648 EW025_RS10500 WP_198462994.1 54088..54183(+) (comS) [Streptococcus pyogenes strain HKU419 isolate HKU419]
ATGTTAAAAAAGTATAAGTACTATTTTATATTCGCAGCTCTACTATCTTTTAAAGTAGTTCAAGAGCTTAGTGCTGTTGA
CTGGTGGCGATTATAA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comS Streptococcus pyogenes MGAS8232

100

100

1

  comS Streptococcus pyogenes MGAS315

45.161

100

0.452


Multiple sequence alignment