Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   EQB41_RS02170 Genome accession   NZ_LR129840
Coordinates   381621..382310 (+) Length   229 a.a.
NCBI ID   WP_061753920.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 4496 isolate 4496     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 376621..387310
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQB41_RS02145 gpsB 376730..377059 (+) 330 WP_000146522.1 cell division regulator GpsB -
  EQB41_RS02155 - 377545..378702 (+) 1158 WP_000711388.1 THUMP domain-containing class I SAM-dependent RNA methyltransferase -
  EQB41_RS02160 mapZ 378715..380109 (+) 1395 WP_127820720.1 cell division site-positioning protein MapZ -
  EQB41_RS02165 gndA 380185..381609 (+) 1425 WP_000158788.1 NADP-dependent phosphogluconate dehydrogenase -
  EQB41_RS02170 covR 381621..382310 (+) 690 WP_061753920.1 response regulator transcription factor Regulator
  EQB41_RS02175 cbpC 382408..383364 (+) 957 WP_050210508.1 choline-binding protein CbpC -
  EQB41_RS02180 - 383482..384714 (-) 1233 WP_127820721.1 MFS transporter -
  EQB41_RS02185 - 384873..385343 (-) 471 WP_001809487.1 lanthionine synthetase LanC family protein -
  EQB41_RS02190 - 385243..385581 (-) 339 WP_001820155.1 lanthionine synthetase LanC family protein -
  EQB41_RS12580 - 386244..386573 (+) 330 WP_000196970.1 transposase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26831.12 Da        Isoelectric Point: 6.9839

>NTDB_id=1116177 EQB41_RS02170 WP_061753920.1 381621..382310(+) (covR) [Streptococcus pneumoniae strain 4496 isolate 4496]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSNIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=1116177 EQB41_RS02170 WP_061753920.1 381621..382310(+) (covR) [Streptococcus pneumoniae strain 4496 isolate 4496]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATTTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGCCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCCTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGACAAA
AAAGCAACATTAAAACCGTGCGTGGTGTTGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.826

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.087

100

0.463

Multiple sequence alignment