Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   HAS68_RS08535 Genome accession   NZ_CP002007
Coordinates   1699585..1700274 (-) Length   229 a.a.
NCBI ID   WP_002942700.1    Uniprot ID   A0A126UNE5
Organism   Streptococcus suis 05HAS68     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1694585..1705274
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HAS68_RS08510 (HAS68_1566) - 1695055..1695768 (-) 714 WP_009910601.1 NADPH-dependent oxidoreductase -
  HAS68_RS08515 (HAS68_1567) dnaI 1695765..1696664 (-) 900 WP_002938337.1 primosomal protein DnaI -
  HAS68_RS08520 (HAS68_1568) - 1696664..1697815 (-) 1152 WP_009910602.1 replication initiation and membrane attachment protein -
  HAS68_RS08525 (HAS68_1569) nrdR 1697802..1698293 (-) 492 WP_002938341.1 transcriptional regulator NrdR -
  HAS68_RS08530 (HAS68_1570) - 1698365..1699495 (-) 1131 WP_013730514.1 AI-2E family transporter -
  HAS68_RS08535 (HAS68_1571) covR 1699585..1700274 (-) 690 WP_002942700.1 winged helix-turn-helix domain-containing protein Regulator
  HAS68_RS08540 (HAS68_1572) gndA 1700356..1701783 (-) 1428 WP_002942698.1 NADP-dependent phosphogluconate dehydrogenase -
  HAS68_RS08545 (HAS68_1573) - 1701880..1702418 (-) 539 Protein_1648 DUF177 domain-containing protein -
  HAS68_RS08550 (HAS68_1574) trxB 1702428..1703345 (-) 918 WP_002942687.1 thioredoxin-disulfide reductase -
  HAS68_RS08555 (HAS68_1575) - 1703359..1703583 (-) 225 WP_002936682.1 DUF4059 family protein -
  HAS68_RS08560 (HAS68_1576) - 1703601..1704944 (-) 1344 WP_002936685.1 DEAD/DEAH box helicase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26225.11 Da        Isoelectric Point: 5.3968

>NTDB_id=111614 HAS68_RS08535 WP_002942700.1 1699585..1700274(-) (covR) [Streptococcus suis 05HAS68]
MAKKILIAGKERNLSHFVSMELQKKDYLVDYASTGKEAMSLAHETDFDLILMSFQLSDMSSKELAAELLAIKPATVMIVV
VEPTEVSQYGEEVLSYAVSYVVKPFVISDLVEQISAIFRGRDFIDNNCKQVHMHAAYRDLKVDFQNRTVTRGDELINLTR
REYDLLATLMNSPEPVSREQLLERVWKYEAASETNVVDVYIRYLRGKLDLPHQDSYIKTVRGVGYAMRD

Nucleotide


Download         Length: 690 bp        

>NTDB_id=111614 HAS68_RS08535 WP_002942700.1 1699585..1700274(-) (covR) [Streptococcus suis 05HAS68]
ATGGCTAAGAAAATTTTGATTGCTGGTAAAGAACGCAATCTCTCGCATTTTGTTTCCATGGAATTGCAGAAAAAAGACTA
TCTTGTTGATTATGCATCGACAGGGAAAGAGGCTATGTCCTTGGCACATGAAACGGATTTTGACTTGATTCTGATGAGTT
TTCAGCTTTCAGACATGTCCAGCAAGGAATTGGCTGCAGAACTATTAGCGATAAAACCAGCCACGGTCATGATTGTGGTA
GTTGAGCCGACAGAAGTTAGTCAATATGGGGAAGAAGTCCTCTCTTATGCTGTTTCCTACGTAGTGAAGCCCTTTGTCAT
CAGTGATTTAGTGGAGCAAATCTCTGCGATTTTTCGTGGTCGTGATTTTATTGACAATAACTGTAAACAGGTTCACATGC
ATGCGGCCTATCGTGATTTGAAGGTTGATTTTCAAAATCGAACAGTGACTCGAGGTGATGAATTGATTAATTTGACCCGC
CGAGAGTATGATCTGTTGGCGACCTTAATGAATAGCCCAGAGCCTGTTAGTCGAGAACAACTTCTTGAGCGTGTTTGGAA
ATATGAAGCGGCTTCTGAGACCAATGTCGTCGATGTATATATTCGCTATCTACGTGGTAAACTGGATTTGCCACATCAAG
ATTCATATATAAAAACAGTTCGTGGTGTCGGATATGCCATGCGCGATTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-227)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A126UNE5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.619

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

41.949

100

0.432

Multiple sequence alignment