Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   E0E10_RS08825 Genome accession   NZ_LR027878
Coordinates   1723159..1723845 (-) Length   228 a.a.
NCBI ID   WP_001792568.1    Uniprot ID   A0A133PXY3
Organism   Staphylococcus aureus strain BPH2003 isolate BPH2003     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1718159..1728845
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E0E10_RS08805 - 1719068..1719484 (-) 417 Protein_1654 ComEC/Rec2 family competence protein -
  E0E10_RS08810 - 1719582..1720754 (+) 1173 WP_000195429.1 IS256-like element IS256 family transposase -
  E0E10_RS08815 - 1720741..1722601 (-) 1861 Protein_1656 ComEC/Rec2 family competence protein -
  E0E10_RS08820 - 1722606..1723067 (-) 462 WP_000439693.1 ComE operon protein 2 -
  E0E10_RS08825 comEA 1723159..1723845 (-) 687 WP_001792568.1 ComEA family DNA-binding protein Machinery gene
  E0E10_RS08830 - 1723885..1724601 (-) 717 WP_000084829.1 class I SAM-dependent DNA methyltransferase -
  E0E10_RS08835 rsfS 1724604..1724957 (-) 354 WP_001088022.1 ribosome silencing factor -
  E0E10_RS08840 yqeK 1724958..1725542 (-) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  E0E10_RS08845 nadD 1725532..1726101 (-) 570 WP_000725162.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  E0E10_RS08850 yhbY 1726104..1726394 (-) 291 WP_000955231.1 ribosome assembly RNA-binding protein YhbY -
  E0E10_RS08855 aroE 1726398..1727204 (-) 807 WP_000666761.1 shikimate dehydrogenase -
  E0E10_RS08860 yqeH 1727218..1728318 (-) 1101 WP_001280148.1 ribosome biogenesis GTPase YqeH -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25863.49 Da        Isoelectric Point: 9.3305

>NTDB_id=1116051 E0E10_RS08825 WP_001792568.1 1723159..1723845(-) (comEA) [Staphylococcus aureus strain BPH2003 isolate BPH2003]
MVLLYQFLLRYKDFLTQWKLYILSAVVLIMVLIGFIFWRQDDYTSRNFENKDTALKQSTSENSSLSKVEDVQVKDGDNSK
NKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLEDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQIEVNSVHEKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTT

Nucleotide


Download         Length: 687 bp        

>NTDB_id=1116051 E0E10_RS08825 WP_001792568.1 1723159..1723845(-) (comEA) [Staphylococcus aureus strain BPH2003 isolate BPH2003]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAATGGAAGTTATATATTCTAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAAATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAAGTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAGGGTCCTGTATATGTCGATGTAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTGGAGGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATACCTCATAAAGGACAAAAGAATGTTGAACCACAAATTGAAGTAAACAGTGTGCACGAAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACGGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTTGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGACATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A133PXY3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus MW2

98.238

99.561

0.978
  comEA Staphylococcus aureus N315

97.357

99.561

0.969

Multiple sequence alignment