Detailed information NTG1116017

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: E0E14_RS10585
• Genome accession: NZ_LR027877
• Coordinates: 2044889..2045932 (-)
• Length: 347 a.a.
• NCBI ID: WP_130828154.1
• Uniprot ID: -
• Organism: Staphylococcus aureus isolate BPH3244
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2039889..2050932

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E0E14_RS10555	-	2040307..2041563 (-)	1257	WP_001795438.1	aminopeptidase	-
E0E14_RS10560	-	2041566..2041766 (-)	201	WP_000180461.1	DUF1128 family protein	-
E0E14_RS10565	-	2041913..2042377 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
E0E14_RS10570	-	2042384..2042659 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
E0E14_RS10575	-	2042937..2044154 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
E0E14_RS10580	vraR	2044270..2044899 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
E0E14_RS10585	vraS	2044889..2045932 (-)	1044	WP_130828154.1	sensor histidine kinase	Regulator
E0E14_RS10590	liaF	2045929..2046630 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
E0E14_RS10595	-	2046645..2047031 (-)	387	WP_001110179.1	hypothetical protein	-
E0E14_RS10600	map	2047248..2048006 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
E0E14_RS10610	-	2048593..2049579 (+)	987	WP_000999713.1	FUSC family protein	-
E0E14_RS10620	-	2050010..2050423 (-)	414	WP_001549145.1	hypothetical protein	-
E0E14_RS10625	-	2050452..2050562 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40030.49 Da
• Isoelectric Point: 6.0577

>NTDB_id=1116017 E0E14_RS10585 WP_130828154.1 2044889..2045932(-) (vraS) [Staphylococcus aureus isolate BPH3244]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIVILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=1116017 E0E14_RS10585 WP_130828154.1 2044889..2045932(-) (vraS) [Staphylococcus aureus isolate BPH3244]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTTTTTTTATTTTTAAATC
TCATCGTCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterProScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	99.712	100	0.997