Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   E0E12_RS08480 Genome accession   NZ_LR027876
Coordinates   1673518..1674204 (-) Length   228 a.a.
NCBI ID   WP_001792568.1    Uniprot ID   A0A133PXY3
Organism   Staphylococcus aureus strain JKD6009 isolate JKD6009     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1668518..1679204
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E0E12_RS08460 rpsT 1669432..1669683 (+) 252 WP_001274017.1 30S ribosomal protein S20 -
  E0E12_RS08465 holA 1669728..1670702 (-) 975 WP_001282562.1 DNA polymerase III subunit delta -
  E0E12_RS08470 comEC 1670759..1672960 (-) 2202 WP_001566051.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  E0E12_RS08475 - 1672965..1673426 (-) 462 WP_000439693.1 ComE operon protein 2 -
  E0E12_RS08480 comEA 1673518..1674204 (-) 687 WP_001792568.1 ComEA family DNA-binding protein Machinery gene
  E0E12_RS08485 - 1674244..1674960 (-) 717 WP_000084829.1 class I SAM-dependent DNA methyltransferase -
  E0E12_RS08490 rsfS 1674963..1675316 (-) 354 WP_001088022.1 ribosome silencing factor -
  E0E12_RS08495 yqeK 1675317..1675901 (-) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  E0E12_RS08500 nadD 1675891..1676460 (-) 570 WP_000725162.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  E0E12_RS08505 yhbY 1676463..1676753 (-) 291 WP_000955231.1 ribosome assembly RNA-binding protein YhbY -
  E0E12_RS08510 aroE 1676757..1677563 (-) 807 WP_000666761.1 shikimate dehydrogenase -
  E0E12_RS08515 yqeH 1677577..1678677 (-) 1101 WP_001280141.1 ribosome biogenesis GTPase YqeH -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25863.49 Da        Isoelectric Point: 9.3305

>NTDB_id=1115965 E0E12_RS08480 WP_001792568.1 1673518..1674204(-) (comEA) [Staphylococcus aureus strain JKD6009 isolate JKD6009]
MVLLYQFLLRYKDFLTQWKLYILSAVVLIMVLIGFIFWRQDDYTSRNFENKDTALKQSTSENSSLSKVEDVQVKDGDNSK
NKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLEDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQIEVNSVHEKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTT

Nucleotide


Download         Length: 687 bp        

>NTDB_id=1115965 E0E12_RS08480 WP_001792568.1 1673518..1674204(-) (comEA) [Staphylococcus aureus strain JKD6009 isolate JKD6009]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAATGGAAGTTATATATTCTAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAAATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAAGTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAGGGTCCTGTATATGTCGATGTAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTGGAGGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATACCTCATAAAGGACAAAAGAATGTTGAACCACAAATTGAAGTAAACAGTGTGCACGAAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACGGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTTGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGACATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A133PXY3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus MW2

98.238

99.561

0.978
  comEA Staphylococcus aureus N315

97.357

99.561

0.969

Multiple sequence alignment