Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   E0E12_RS02995 Genome accession   NZ_LR027876
Coordinates   594251..594820 (+) Length   189 a.a.
NCBI ID   WP_000872873.1    Uniprot ID   -
Organism   Staphylococcus aureus strain JKD6009 isolate JKD6009     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 589251..599820
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E0E12_RS02970 cysE 590464..591111 (+) 648 WP_001838365.1 serine O-acetyltransferase -
  E0E12_RS02975 cysS 591095..592495 (+) 1401 WP_000631964.1 cysteine--tRNA ligase -
  E0E12_RS02980 - 592488..592892 (+) 405 WP_000370182.1 Mini-ribonuclease 3 -
  E0E12_RS02985 rlmB 592900..593646 (+) 747 WP_000390328.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  E0E12_RS02990 - 593646..594170 (+) 525 WP_000664738.1 NYN domain-containing protein -
  E0E12_RS02995 sigH 594251..594820 (+) 570 WP_000872873.1 sigma-70 family RNA polymerase sigma factor Regulator
  E0E12_RS03000 rpmG 594935..595078 (+) 144 WP_001788193.1 50S ribosomal protein L33 -
  E0E12_RS03005 secE 595134..595316 (+) 183 WP_001074474.1 preprotein translocase subunit SecE -
  E0E12_RS03010 nusG 595329..595877 (+) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  E0E12_RS03015 rplK 596058..596480 (+) 423 WP_001085792.1 50S ribosomal protein L11 -
  E0E12_RS03020 rplA 596688..597380 (+) 693 WP_001074619.1 50S ribosomal protein L1 -
  E0E12_RS03030 rplJ 597652..598152 (+) 501 WP_001273085.1 50S ribosomal protein L10 -
  E0E12_RS03035 rplL 598195..598563 (+) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  E0E12_RS03040 - 598738..599346 (+) 609 WP_000020304.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23028.91 Da        Isoelectric Point: 9.4170

>NTDB_id=1115946 E0E12_RS02995 WP_000872873.1 594251..594820(+) (sigH) [Staphylococcus aureus strain JKD6009 isolate JKD6009]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRFDVENNYLNKLAIKELICQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=1115946 E0E12_RS02995 WP_000872873.1 594251..594820(+) (sigH) [Staphylococcus aureus strain JKD6009 isolate JKD6009]
TTGAAATACGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTTTGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTTGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAATTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus N315

99.471

100

0.995
  sigH Staphylococcus aureus MW2

98.413

100

0.984

Multiple sequence alignment