Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   E0E13_RS08485 Genome accession   NZ_LR027874
Coordinates   1677574..1678260 (-) Length   228 a.a.
NCBI ID   WP_001792568.1    Uniprot ID   A0A133PXY3
Organism   Staphylococcus aureus strain BPH2056 isolate BPH2056     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1672574..1683260
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E0E13_RS08465 rpsT 1673488..1673739 (+) 252 WP_001274017.1 30S ribosomal protein S20 -
  E0E13_RS08470 holA 1673784..1674758 (-) 975 WP_001282562.1 DNA polymerase III subunit delta -
  E0E13_RS08475 comEC 1674815..1677016 (-) 2202 WP_001566051.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  E0E13_RS08480 - 1677021..1677482 (-) 462 WP_000439693.1 ComE operon protein 2 -
  E0E13_RS08485 comEA 1677574..1678260 (-) 687 WP_001792568.1 ComEA family DNA-binding protein Machinery gene
  E0E13_RS08490 - 1678300..1679016 (-) 717 WP_000084829.1 class I SAM-dependent DNA methyltransferase -
  E0E13_RS08495 rsfS 1679019..1679372 (-) 354 WP_001088022.1 ribosome silencing factor -
  E0E13_RS08500 yqeK 1679373..1679957 (-) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  E0E13_RS08505 nadD 1679947..1680516 (-) 570 WP_000725162.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  E0E13_RS08510 yhbY 1680519..1680809 (-) 291 WP_000955231.1 ribosome assembly RNA-binding protein YhbY -
  E0E13_RS08515 aroE 1680813..1681619 (-) 807 WP_000666761.1 shikimate dehydrogenase -
  E0E13_RS08520 yqeH 1681633..1682733 (-) 1101 WP_001280141.1 ribosome biogenesis GTPase YqeH -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25863.49 Da        Isoelectric Point: 9.3305

>NTDB_id=1115922 E0E13_RS08485 WP_001792568.1 1677574..1678260(-) (comEA) [Staphylococcus aureus strain BPH2056 isolate BPH2056]
MVLLYQFLLRYKDFLTQWKLYILSAVVLIMVLIGFIFWRQDDYTSRNFENKDTALKQSTSENSSLSKVEDVQVKDGDNSK
NKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLEDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQIEVNSVHEKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTT

Nucleotide


Download         Length: 687 bp        

>NTDB_id=1115922 E0E13_RS08485 WP_001792568.1 1677574..1678260(-) (comEA) [Staphylococcus aureus strain BPH2056 isolate BPH2056]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAATGGAAGTTATATATTCTAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAAATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAAGTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAGGGTCCTGTATATGTCGATGTAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTGGAGGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATACCTCATAAAGGACAAAAGAATGTTGAACCACAAATTGAAGTAAACAGTGTGCACGAAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACGGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTTGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGACATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A133PXY3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus MW2

98.238

99.561

0.978
  comEA Staphylococcus aureus N315

97.357

99.561

0.969

Multiple sequence alignment