Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   E0E08_RS08670 Genome accession   NZ_LR027873
Coordinates   1709586..1710272 (-) Length   228 a.a.
NCBI ID   WP_001792568.1    Uniprot ID   A0A133PXY3
Organism   Staphylococcus aureus strain BPH2070 isolate BPH2070     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1704586..1715272
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E0E08_RS08645 - 1705495..1705977 (-) 483 Protein_1626 ComEC/Rec2 family competence protein -
  E0E08_RS08655 - 1706079..1707251 (+) 1173 WP_000195429.1 IS256-like element IS256 family transposase -
  E0E08_RS08660 - 1707304..1709028 (-) 1725 Protein_1628 ComEC/Rec2 family competence protein -
  E0E08_RS08665 - 1709033..1709494 (-) 462 WP_000439693.1 ComE operon protein 2 -
  E0E08_RS08670 comEA 1709586..1710272 (-) 687 WP_001792568.1 ComEA family DNA-binding protein Machinery gene
  E0E08_RS08675 - 1710312..1711028 (-) 717 WP_000084829.1 class I SAM-dependent DNA methyltransferase -
  E0E08_RS08680 rsfS 1711031..1711384 (-) 354 WP_001088022.1 ribosome silencing factor -
  E0E08_RS08685 yqeK 1711385..1711969 (-) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  E0E08_RS08690 nadD 1711959..1712528 (-) 570 WP_000725162.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  E0E08_RS08695 yhbY 1712531..1712821 (-) 291 WP_000955231.1 ribosome assembly RNA-binding protein YhbY -
  E0E08_RS08700 aroE 1712825..1713631 (-) 807 WP_000666761.1 shikimate dehydrogenase -
  E0E08_RS08705 yqeH 1713645..1714745 (-) 1101 WP_001280141.1 ribosome biogenesis GTPase YqeH -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25863.49 Da        Isoelectric Point: 9.3305

>NTDB_id=1115879 E0E08_RS08670 WP_001792568.1 1709586..1710272(-) (comEA) [Staphylococcus aureus strain BPH2070 isolate BPH2070]
MVLLYQFLLRYKDFLTQWKLYILSAVVLIMVLIGFIFWRQDDYTSRNFENKDTALKQSTSENSSLSKVEDVQVKDGDNSK
NKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLEDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQIEVNSVHEKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTT

Nucleotide


Download         Length: 687 bp        

>NTDB_id=1115879 E0E08_RS08670 WP_001792568.1 1709586..1710272(-) (comEA) [Staphylococcus aureus strain BPH2070 isolate BPH2070]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAATGGAAGTTATATATTCTAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAAATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAAGTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAGGGTCCTGTATATGTCGATGTAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTGGAGGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATACCTCATAAAGGACAAAAGAATGTTGAACCACAAATTGAAGTAAACAGTGTGCACGAAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACGGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTTGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGACATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A133PXY3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus MW2

98.238

99.561

0.978
  comEA Staphylococcus aureus N315

97.357

99.561

0.969

Multiple sequence alignment