Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   E0E15_RS08500 Genome accession   NZ_LR027870
Coordinates   1680079..1680765 (-) Length   228 a.a.
NCBI ID   WP_001792568.1    Uniprot ID   A0A133PXY3
Organism   Staphylococcus aureus strain BPH2019 isolate BPH2019     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1675079..1685765
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E0E15_RS08480 rpsT 1675993..1676244 (+) 252 WP_001274017.1 30S ribosomal protein S20 -
  E0E15_RS08485 holA 1676289..1677263 (-) 975 WP_001282562.1 DNA polymerase III subunit delta -
  E0E15_RS08490 comEC 1677320..1679521 (-) 2202 WP_001566051.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  E0E15_RS08495 - 1679526..1679987 (-) 462 WP_000439693.1 ComE operon protein 2 -
  E0E15_RS08500 comEA 1680079..1680765 (-) 687 WP_001792568.1 ComEA family DNA-binding protein Machinery gene
  E0E15_RS08505 - 1680805..1681521 (-) 717 WP_000084829.1 class I SAM-dependent DNA methyltransferase -
  E0E15_RS08510 rsfS 1681524..1681877 (-) 354 WP_001088022.1 ribosome silencing factor -
  E0E15_RS08515 yqeK 1681878..1682462 (-) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  E0E15_RS08520 nadD 1682452..1683021 (-) 570 WP_000725162.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  E0E15_RS08525 yhbY 1683024..1683314 (-) 291 WP_000955231.1 ribosome assembly RNA-binding protein YhbY -
  E0E15_RS08530 aroE 1683318..1684124 (-) 807 WP_000666761.1 shikimate dehydrogenase -
  E0E15_RS08535 yqeH 1684138..1685238 (-) 1101 WP_001280141.1 ribosome biogenesis GTPase YqeH -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25863.49 Da        Isoelectric Point: 9.3305

>NTDB_id=1115837 E0E15_RS08500 WP_001792568.1 1680079..1680765(-) (comEA) [Staphylococcus aureus strain BPH2019 isolate BPH2019]
MVLLYQFLLRYKDFLTQWKLYILSAVVLIMVLIGFIFWRQDDYTSRNFENKDTALKQSTSENSSLSKVEDVQVKDGDNSK
NKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLEDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQIEVNSVHEKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTT

Nucleotide


Download         Length: 687 bp        

>NTDB_id=1115837 E0E15_RS08500 WP_001792568.1 1680079..1680765(-) (comEA) [Staphylococcus aureus strain BPH2019 isolate BPH2019]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAATGGAAGTTATATATTCTAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAAATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAAGTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAGGGTCCTGTATATGTCGATGTAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTGGAGGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATACCTCATAAAGGACAAAAGAATGTTGAACCACAAATTGAAGTAAACAGTGTGCACGAAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACGGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTTGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGACATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A133PXY3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus MW2

98.238

99.561

0.978
  comEA Staphylococcus aureus N315

97.357

99.561

0.969

Multiple sequence alignment