Detailed information NTG1115813

Bioinformatically predicted

Overview

• Name: ccrB
• Type: Machinery gene
• Locus tag: E0E15_RS00315
• Genome accession: NZ_LR027870
• Coordinates: 62413..64041 (-)
• Length: 542 a.a.
• NCBI ID: WP_001186596.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain BPH2019 isolate BPH2019
• Function: promote SCCmec transfer (predicted from homology) Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
SCCmec	44250..65408	62413..64041	within	0

Gene organization within MGE regions

Location: 44250..65408

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E0E15_RS00210	mecA	44250..46259 (-)	2010	WP_001801873.1	PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA	-
E0E15_RS00215	mecR1	46356..48113 (+)	1758	WP_000952923.1	beta-lactam sensor/signal transducer MecR1	-
E0E15_RS00220	-	48113..48424 (+)	312	WP_116100490.1	BlaI/MecI/CopY family transcriptional regulator	-
E0E15_RS00225	psm-mec	48569..48637 (-)	69	WP_014532405.1	phenol-soluble modulin PSM-mec	-
E0E15_RS00230	-	48971..50101 (+)	1131	WP_010922808.1	ROK family transcriptional regulator	-
E0E15_RS00235	cstB	50215..51549 (-)	1335	Protein_40	persulfide dioxygenase-sulfurtransferase CstB	-
E0E15_RS00240	-	51582..52646 (-)	1065	WP_000438836.1	DsrE/DsrF/DrsH-like family protein	-
E0E15_RS00245	cstR	52782..53042 (+)	261	WP_000220507.1	persulfide-sensing transcriptional repressor CstR	-
E0E15_RS00250	-	53042..53680 (+)	639	Protein_43	sulfite exporter TauE/SafE family protein	-
E0E15_RS00260	-	53954..54570 (-)	617	Protein_44	CadD family cadmium resistance transporter	-
E0E15_RS00265	-	54651..57065 (-)	2415	WP_116100491.1	cadmium-translocating P-type ATPase CadA	-
E0E15_RS00270	-	57058..57423 (-)	366	WP_000159127.1	ArsR/SmtB family transcription factor	-
E0E15_RS00275	-	57661..58038 (-)	378	WP_001041908.1	DUF6262 family protein	-
E0E15_RS00280	-	58045..59937 (-)	1893	WP_002485298.1	site-specific integrase	-
E0E15_RS00285	-	60132..60455 (-)	324	WP_000088091.1	JAB domain-containing protein	-
E0E15_RS00290	-	60448..60654 (-)	207	WP_001077283.1	hypothetical protein	-
E0E15_RS00295	-	60656..61177 (-)	522	WP_000836008.1	DUF1643 domain-containing protein	-
E0E15_RS00300	-	61196..61507 (-)	312	WP_000833212.1	DUF960 family protein	-
E0E15_RS00310	-	61592..61942 (-)	351	WP_000171449.1	SAUGI family uracil-DNA glycosylase inhibitor	-
E0E15_RS00315	ccrB	62413..64041 (-)	1629	WP_001186596.1	cassette chromosome recombinase CcrB	Machinery gene
E0E15_RS00320	ccrA	64062..65408 (-)	1347	WP_000816499.1	cassette chromosome recombinase CcrA	Machinery gene

Sequence

Protein

• Length: 542 a.a.
• Molecular weight: 62274.15 Da
• Isoelectric Point: 9.7334

>NTDB_id=1115813 E0E15_RS00315 WP_001186596.1 62413..64041(-) (ccrB) [Staphylococcus aureus strain BPH2019 isolate BPH2019]
MQQLKQKRVGIYVRVSTEIQSTEGYSIDGQINQIREYCDFNNFVVVDVYADRGISGKSMNRPELQRLLKDANEGQIDSVM
VYKTNRLARNTSDLLKIVEDLHRQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPDSKHELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGKPFSIGSVTYILSNPFYVGKIQFAK
YKDWNEKRRKGLNDKPIIAEGKHSPIIIQDLWDKVQLRKKQVSQKPQVHGKGTNLLTGIVHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEKYVMDQILEIVKSDKVINQVLERVNQENKVDIGALNHDIAYKQQQYD
EVSGKLHNLVKTIEDNPDLTSALKATIHQYETQLNDITNQMNQLKQQQNQEKLSYDTKQIAALLQRIFQNIESMDKAQLK
ALYLTVIDRIDIRKDGNHKKQFYVTLKLNNEIIKQLFNNTPLDEVLLSTSSLFLPQTLFLQI

Nucleotide

• Length: 1629 bp

>NTDB_id=1115813 E0E15_RS00315 WP_001186596.1 62413..64041(-) (ccrB) [Staphylococcus aureus strain BPH2019 isolate BPH2019]
ATGCAACAACTCAAACAAAAACGTGTCGGTATCTATGTTCGTGTATCAACGGAAATCCAAAGTACTGAAGGCTATAGTAT
CGATGGACAAATCAATCAAATTCGAGAATATTGTGATTTCAATAACTTTGTTGTTGTAGATGTATACGCGGATAGAGGTA
TCTCTGGAAAATCTATGAACCGACCAGAACTACAACGTTTGTTAAAAGATGCGAACGAAGGTCAGATTGATTCTGTTATG
GTCTACAAAACAAACCGACTAGCACGTAACACTTCTGACTTACTCAAAATTGTTGAAGACCTTCATCGTCAAAATGTCGA
ATTCTTCAGCTTATCTGAGCGTATGGAAGTCAATACAAGCAGTGGTAAATTGATGCTACAAATTCTAGCGAGTTTTTCAG
AATTTGAAAGAAATAATATTGTCGAAAATGTATTCATGGGTCAAACCCGACGCGCTCAAGAAGGCTATTATCAAGGCAAT
TTGCCGCTGGGCTATGACAAAATACCGGATAGCAAGCATGAACTCATGATAAACCAACATGAAGCGAATATTGTCAAATA
TATATTTGAGTCATATGCTAAAGGCCACGGATATCGTAAAATTGCGAATGCACTCAATCACAAAGGATACGTGACTAAAA
AAGGAAAGCCTTTCAGTATTGGTTCAGTGACCTATATCTTATCTAATCCATTCTATGTTGGTAAAATTCAATTCGCAAAG
TACAAAGATTGGAATGAAAAGCGTCGTAAAGGGCTGAATGATAAACCAATAATAGCTGAAGGTAAGCATTCCCCTATTAT
TATTCAAGACTTATGGGATAAAGTCCAATTACGTAAAAAACAAGTCAGTCAAAAACCTCAAGTCCACGGTAAAGGAACTA
ATCTATTAACAGGTATCGTTCATTGTCCACAATGTGGTGCACCAATGGCAGCTAGTAACACAACGAACACATTGAAAGAT
GGTACCAAGAAGCGAATACGTTATTATTCTTGCAGTAACTTCCGAAACAAAGGCTCAAAAGTATGTTCTGCGAATAGCGT
TAGAGCTGATGTGATTGAGAAATACGTCATGGATCAAATACTCGAAATTGTCAAAAGTGATAAAGTCATTAACCAAGTCT
TAGAACGTGTCAATCAAGAAAATAAAGTCGATATTGGTGCATTGAACCACGATATCGCTTATAAACAACAACAATACGAT
GAAGTCAGCGGGAAACTCCATAATTTAGTTAAAACCATTGAAGATAATCCGGACCTAACATCTGCATTGAAAGCAACTAT
TCATCAATATGAAACACAACTCAATGACATTACAAATCAAATGAATCAACTCAAACAGCAACAAAATCAAGAGAAACTAT
CTTATGATACGAAACAAATCGCTGCCCTATTACAACGAATATTTCAAAATATAGAATCAATGGATAAAGCACAACTCAAA
GCATTATATCTTACAGTCATTGACCGTATTGATATTCGTAAAGACGGTAATCATAAAAAACAGTTCTACGTTACACTAAA
ACTCAATAATGAAATTATTAAACAACTTTTCAATAATACCCCTCTCGACGAAGTGCTCCTCAGCACTTCGTCTTTATTTT
TGCCTCAAACGCTCTTTCTTCAAATCTAA

Domains

Predicted by InterproScan.

• Resolvase, N terminal domain (Resolvase) (11-156)

• Recombinase (Recombinase) (180-280)

• Ogr/Delta-like zinc finger (Ogr_Delta) (301-356)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccrB	Staphylococcus aureus N315	86.531	100	0.865