Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   E0E09_RS08500 Genome accession   NZ_LR027869
Coordinates   1678506..1679192 (-) Length   228 a.a.
NCBI ID   WP_001792568.1    Uniprot ID   A0A133PXY3
Organism   Staphylococcus aureus isolate BPH2869     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1673506..1684192
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E0E09_RS08480 rpsT 1674420..1674671 (+) 252 WP_001274017.1 30S ribosomal protein S20 -
  E0E09_RS08485 holA 1674716..1675690 (-) 975 WP_001282562.1 DNA polymerase III subunit delta -
  E0E09_RS08490 comEC 1675747..1677948 (-) 2202 WP_001566051.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  E0E09_RS08495 - 1677953..1678414 (-) 462 WP_000439693.1 ComE operon protein 2 -
  E0E09_RS08500 comEA 1678506..1679192 (-) 687 WP_001792568.1 ComEA family DNA-binding protein Machinery gene
  E0E09_RS08505 - 1679232..1679948 (-) 717 WP_000084829.1 class I SAM-dependent DNA methyltransferase -
  E0E09_RS08510 rsfS 1679951..1680304 (-) 354 WP_001088022.1 ribosome silencing factor -
  E0E09_RS08515 yqeK 1680305..1680889 (-) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  E0E09_RS08520 nadD 1680879..1681448 (-) 570 WP_000725162.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  E0E09_RS08525 yhbY 1681451..1681741 (-) 291 WP_000955231.1 ribosome assembly RNA-binding protein YhbY -
  E0E09_RS08530 aroE 1681745..1682551 (-) 807 WP_000666761.1 shikimate dehydrogenase -
  E0E09_RS08535 yqeH 1682565..1683665 (-) 1101 WP_001280141.1 ribosome biogenesis GTPase YqeH -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25863.49 Da        Isoelectric Point: 9.3305

>NTDB_id=1115792 E0E09_RS08500 WP_001792568.1 1678506..1679192(-) (comEA) [Staphylococcus aureus isolate BPH2869]
MVLLYQFLLRYKDFLTQWKLYILSAVVLIMVLIGFIFWRQDDYTSRNFENKDTALKQSTSENSSLSKVEDVQVKDGDNSK
NKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLEDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQIEVNSVHEKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTT

Nucleotide


Download         Length: 687 bp        

>NTDB_id=1115792 E0E09_RS08500 WP_001792568.1 1678506..1679192(-) (comEA) [Staphylococcus aureus isolate BPH2869]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAATGGAAGTTATATATTCTAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAAATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAAGTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAGGGTCCTGTATATGTCGATGTAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTGGAGGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATACCTCATAAAGGACAAAAGAATGTTGAACCACAAATTGAAGTAAACAGTGTGCACGAAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACGGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTTGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGACATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A133PXY3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus MW2

98.238

99.561

0.978
  comEA Staphylococcus aureus N315

97.357

99.561

0.969

Multiple sequence alignment