Detailed information NTG1114595

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: A66_RS08850
• Genome accession: NZ_LN847353
• Coordinates: 1684316..1685380 (-)
• Length: 354 a.a.
• NCBI ID: WP_053039757.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain A66
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1679316..1690380

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A66_RS08830 (A66_01758)	-	1680055..1681386 (-)	1332	WP_000390049.1	hemolysin family protein	-
A66_RS08835 (A66_01759)	endA	1681677..1682501 (-)	825	WP_001036790.1	DNA-entry nuclease EndA	Machinery gene
A66_RS08840 (A66_01760)	-	1682540..1682728 (-)	189	WP_001036519.1	DNA-directed RNA polymerase subunit beta	-
A66_RS08845 (A66_01761)	murA	1682721..1684004 (-)	1284	WP_000358027.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
A66_RS11345 (A66_01762)	-	1684028..1684258 (-)	231	WP_000250392.1	DUF1146 family protein	-
A66_RS08850 (A66_01763)	sepM	1684316..1685380 (-)	1065	WP_053039757.1	SepM family pheromone-processing serine protease	Regulator
A66_RS08855 (A66_01764)	coaD	1685364..1685852 (-)	489	WP_053039758.1	pantetheine-phosphate adenylyltransferase	-
A66_RS08860 (A66_01765)	rsmD	1685842..1686381 (-)	540	WP_000706960.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
A66_RS08865 (A66_01766)	asnA	1686446..1687438 (-)	993	WP_000747993.1	aspartate--ammonia ligase	-
A66_RS08875 (A66_01767)	-	1687550..1688233 (-)	684	WP_001016913.1	Bax inhibitor-1/YccA family protein	-
A66_RS08880 (A66_01768)	-	1688289..1689029 (-)	741	WP_053039759.1	RNA methyltransferase	-
A66_RS08885 (A66_01769)	-	1689063..1689341 (+)	279	WP_001174613.1	acylphosphatase	-
A66_RS08890 (A66_01770)	yidC	1689419..1690345 (+)	927	WP_000835941.1	membrane protein insertase YidC	-

Sequence

Protein

• Length: 354 a.a.
• Molecular weight: 38515.64 Da
• Isoelectric Point: 5.0813

>NTDB_id=1114595 A66_RS08850 WP_053039757.1 1684316..1685380(-) (sepM) [Streptococcus pneumoniae strain A66]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFMRINQFYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVISNVPISFSTAGIGG
PSAGLMFSLAIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNN
YQTALEAAKTIKTDMKIVPVKTLQDAIDYLKNNP

Nucleotide

• Length: 1065 bp

>NTDB_id=1114595 A66_RS08850 WP_053039757.1 1684316..1685380(-) (sepM) [Streptococcus pneumoniae strain A66]
ATGAAAAAAAAGATTAGATGGCCCTTATACGTCATTGCGGCCTTGATTGTGACTTTCTTGGCATTTGTAGTGCCCTTGCC
TTATTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCCACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTATGCGAATCAATCAATTCTACATGCAAAC
ATCGCAAAATATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGATATCGAACTCAAGTACTTTGGCGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTAAAGGGATTCTCAATATCTCTGATACAGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGATTACGTCAGTTCTCAAAAATTAGGGGATTC
CGTCAAGGTCACCTATGAAGAGGATGGGCAAACCAAGTCTGCAGAAGGAAAGATTATCACCTTGGAAAATGGAAAAAATG
GGATTGGAATCGGCTTGATTGATCGTACAGAGGTAATCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGT
CCAAGTGCTGGTCTCATGTTTAGTCTAGCTATCTATACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGC
CGGTACAGGTACCATTGACCGCGATGGTAATGTGGGAGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGG
CAGGTGCTGCTATTTTCTTTGCTCCTGATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCCGGACGCGAAAAACAAC
TACCAAACAGCCCTAGAAGCGGCTAAAACAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGAT
TGATTACTTGAAAAACAATCCCTAA

Domains

Predicted by InterproScan.

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (240-305)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	58.405	99.153	0.579