Detailed information    

insolico Bioinformatically predicted

Overview

Name   comM   Type   Regulator
Locus tag   A66_RS08780 Genome accession   NZ_LN847353
Coordinates   1665579..1666199 (-) Length   206 a.a.
NCBI ID   WP_000839908.1    Uniprot ID   A0A0B7M636
Organism   Streptococcus pneumoniae strain A66     
Function   fratricide immunity (predicted from homology)   
Competence regulation

Genomic Context

Location: 1660579..1671199
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A66_RS08755 (A66_01743) recA 1660956..1662122 (-) 1167 WP_001085462.1 recombinase RecA Machinery gene
  A66_RS08760 (A66_01744) cinA 1662177..1663433 (-) 1257 WP_000642707.1 competence/damage-inducible protein A Machinery gene
  A66_RS08765 (A66_01745) brpA 1663518..1664534 (-) 1017 WP_000239282.1 biofilm formation/cell division transcriptional regulator BrpA -
  A66_RS08770 (A66_01746) - 1664542..1665060 (-) 519 WP_053039755.1 GNAT family N-acetyltransferase -
  A66_RS08775 (A66_01747) tsaE 1665050..1665493 (-) 444 WP_000288232.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  A66_RS08780 (A66_01748) comM 1665579..1666199 (-) 621 WP_000839908.1 hypothetical protein Regulator
  A66_RS08785 (A66_01750) - 1666582..1667445 (-) 864 WP_001093620.1 helix-turn-helix domain-containing protein -
  A66_RS12805 (A66_01751) - 1667634..1667804 (+) 171 WP_000742180.1 PhrA family quorum-sensing system peptide -
  A66_RS08795 (A66_01752) - 1667949..1669964 (+) 2016 WP_053039756.1 DUF1430 domain-containing protein -
  A66_RS08800 (A66_01753) - 1669966..1670598 (+) 633 WP_000571419.1 ABC transporter ATP-binding protein -
  A66_RS12940 (A66_01754) - 1670739..1671017 (+) 279 WP_000712962.1 hypothetical protein -

Sequence

Protein


Download         Length: 206 a.a.        Molecular weight: 23552.72 Da        Isoelectric Point: 10.1254

>NTDB_id=1114593 A66_RS08780 WP_000839908.1 1665579..1666199(-) (comM) [Streptococcus pneumoniae strain A66]
MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFVSGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLL
INLLGAVLVLSDNLFIKNTLQQELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF

Nucleotide


Download         Length: 621 bp        

>NTDB_id=1114593 A66_RS08780 WP_000839908.1 1665579..1666199(-) (comM) [Streptococcus pneumoniae strain A66]
ATGAAATCAATGAGAATCTTATTTTTGTTAGCTTTAATTCAAATCAGTTTGAGTAGCTGTTTCCTATGGAAGGAATGCAT
CTTGTCCTTTAAACAAAGTACAGCTTTTTTCATCGGAAGCATGGTTTTCGTTTCAGGAATCTGTGCTGGAGTAAATTATC
TTTATACCCGTAAGCAAGAAGTCCATAGTGTCCTAGCCAGTAAGAAGTCGGTGAAGCTTTTTTACAGTATGTTACTCTTA
ATTAATTTGTTAGGAGCTGTTCTTGTTTTGTCAGATAACTTGTTCATCAAAAATACGCTGCAGCAAGAATTAGTTGACTT
TTTATTGCCATCCTTCTTTTTCCTATTTGGGCTAGATTTGCTGATTTTTTTACCCTTGAAAAAATACGTGCGCGATTTTC
TTGCTATGCTGGACAGAAAAAAGACAGTGTTGGTGACTATTTTAGCAACACTTCTTTTCTTAAGAAATCCAATGACCATT
GTCTCACTTCTGATTTATATTGGACTGGGCTTGTTTTTTGCAGCCTATCTTGTCCCAAATTCGGTTAAGAAGGAAGTTTC
CTTTTATGGTCATATTTTCCGAGATCTTGTATTGGTCATTGTTACGCTCATTTTCTTTTAG

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7M636

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comM Streptococcus pneumoniae D39

100

100

1
  comM Streptococcus pneumoniae R6

100

100

1
  comM Streptococcus pneumoniae TIGR4

100

100

1
  comM Streptococcus mitis NCTC 12261

38.974

94.66

0.369
  comM Streptococcus mitis SK321

38.974

94.66

0.369

Multiple sequence alignment