Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   A66_RS06995 Genome accession   NZ_LN847353
Coordinates   1355409..1356641 (-) Length   410 a.a.
NCBI ID   WP_053039682.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain A66     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1350409..1361641
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A66_RS06965 (A66_01398) - 1350596..1351564 (+) 969 WP_053039681.1 NAD(P)/FAD-dependent oxidoreductase -
  A66_RS06970 (A66_01399) whiA 1351598..1352509 (-) 912 WP_000011276.1 DNA-binding protein WhiA -
  A66_RS06975 (A66_01400) - 1352506..1353483 (-) 978 WP_001232645.1 YvcK family protein -
  A66_RS06980 (A66_01401) rapZ 1353480..1354370 (-) 891 WP_000163037.1 RNase adapter RapZ -
  A66_RS06985 (A66_01402) - 1354422..1354802 (-) 381 WP_001140412.1 RidA family protein -
  A66_RS06990 (A66_01403) yihA 1354813..1355400 (-) 588 WP_050212754.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  A66_RS06995 (A66_01404) clpX 1355409..1356641 (-) 1233 WP_053039682.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  A66_RS07000 (A66_01405) - 1356673..1356843 (-) 171 WP_000442275.1 hypothetical protein -
  A66_RS07005 (A66_01406) - 1356843..1357349 (-) 507 WP_000162484.1 dihydrofolate reductase -
  A66_RS07010 (A66_01407) - 1357479..1357997 (-) 519 WP_000229872.1 DNA starvation/stationary phase protection protein -
  A66_RS07015 (A66_01408) lytC 1358494..1359998 (-) 1505 Protein_1381 choline binding-anchored murein hydrolase LytC -
  A66_RS07020 (A66_01410) tpiA 1360036..1360794 (-) 759 WP_053039683.1 triose-phosphate isomerase -
  A66_RS07025 (A66_01411) - 1360892..1361569 (-) 678 WP_053039684.1 DnaD domain-containing protein -

Sequence

Protein


Download         Length: 410 a.a.        Molecular weight: 45814.35 Da        Isoelectric Point: 4.4550

>NTDB_id=1114577 A66_RS06995 WP_053039682.1 1355409..1356641(-) (clpX) [Streptococcus pneumoniae strain A66]
MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQEIIREELVEEVLSDLSEVPKPIELLHILNHYVIGQDR
AKRALAVAVYNHYKRINFHDTREESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDT
KNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKALDENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVR
ILKEPRNALVKQYQTLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLVRITKETVD
GTDKPILETA

Nucleotide


Download         Length: 1233 bp        

>NTDB_id=1114577 A66_RS06995 WP_053039682.1 1355409..1356641(-) (clpX) [Streptococcus pneumoniae strain A66]
ATGTCTACAAATAGAAAAAATGATATGATGGTTTATTGCTCATTTTGTGGCAAAAACCAAGAAGAAGTACAAAAAATAAT
TGCTGGCAACAATGCTTTTATTTGTAATGAATGCGTGGAGTTAGCTCAGGAAATCATTCGAGAAGAATTGGTTGAGGAAG
TCTTGTCAGACTTGTCTGAGGTGCCAAAACCAATTGAACTCCTCCATATCTTGAACCACTATGTAATTGGTCAAGATCGT
GCCAAGCGTGCCTTGGCAGTGGCGGTTTATAACCACTACAAACGCATCAATTTCCACGATACACGCGAAGAGTCAGAAGA
TGTGGATTTGCAGAAGTCAAACATTTTGATGATTGGCCCAACTGGTTCAGGGAAAACTTTCCTTGCCCAGACCTTGGCTA
AGAGCTTGAATGTGCCTTTTGCTATTGCGGATGCGACAGCTCTGACGGAGGCTGGTTATGTGGGTGAGGACGTGGAAAAT
ATCCTCCTCAAACTCTTGCAGGTTGCTGACTTTAACATCGAACGTGCAGAGCGTGGCATTATCTATGTGGATGAAATTGA
CAAGATTGCCAAGAAGAGTGAGAATGTGTCTATCACACGTGATGTTTCTGGTGAAGGGGTGCAACAAGCCCTTCTCAAGA
TTATCGAGGGAACTGTTGCTAGCGTGCCGCCTCAAGGTGGACGCAAACATCCACAACAAGAGATGATTCAAGTGGATACA
AAAAATATCCTCTTCATCGTGGGTGGTGCTTTTGATGGTATTGAAGAAATTGTCAAACAACGTCTGGGTGAAAAAGTCAT
CGGATTTGGTCAAAACAATAAGGCGCTTGACGAAAACAGCTCATATATGCAAGAAATCATCGCTGAAGACATTCAAAAAT
TTGGTATTATCCCTGAGTTGATTGGACGCTTGCCTGTTTTTGCGGCTCTTGAGCAATTGACCGTTGATGACTTGGTTCGC
ATCTTGAAAGAGCCAAGAAATGCCTTGGTGAAACAATACCAAACTTTGCTTTCTTATGATGATGTTGAGTTGGAATTTGA
CGACGAAGCCCTTCAAGAGATTGCTAATAAAGCAATCGAACGGAAGACAGGGGCGCGTGGACTTCGCTCCATTATCGAAG
AAACCATGCTAGATGTTATGTTTGAGGTGCCGAGTCAGGAAAATGTGAAATTGGTTCGCATCACTAAAGAAACTGTCGAT
GGAACGGATAAACCGATCCTAGAAACAGCCTAG

Domains

Predicted by InterproScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(313-390)

AAA domain (Cdc48 subfamily) (AAA_2)

(111-306)

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

86.098

100

0.861
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

57.463

98.049

0.563

Multiple sequence alignment