Detailed information    

insolico Bioinformatically predicted

Overview

Name   pptA   Type   Regulator
Locus tag   A66_RS02400 Genome accession   NZ_LN847353
Coordinates   456048..456779 (+) Length   243 a.a.
NCBI ID   WP_000889919.1    Uniprot ID   A0A062WNF5
Organism   Streptococcus pneumoniae strain A66     
Function   export ComS (predicted from homology)   
Competence regulation

Genomic Context

Location: 451048..461779
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A66_RS02380 - 452607..452876 (+) 270 WP_225791136.1 hypothetical protein -
  A66_RS02385 (A66_00475) dnaJ 453363..454499 (+) 1137 WP_053039476.1 molecular chaperone DnaJ -
  A66_RS12100 (A66_00476) - 454935..455111 (-) 177 WP_014931964.1 hypothetical protein -
  A66_RS02390 (A66_00477) - 455273..455560 (-) 288 WP_000777751.1 hypothetical protein -
  A66_RS02395 (A66_00478) - 455570..455980 (-) 411 WP_001278301.1 HIT family protein -
  A66_RS02400 (A66_00479) pptA 456048..456779 (+) 732 WP_000889919.1 ABC transporter ATP-binding protein Regulator
  A66_RS02405 (A66_00480) - 456776..457825 (+) 1050 WP_000653777.1 ABC transporter permease -
  A66_RS02410 (A66_00481) - 457886..458215 (-) 330 WP_000132573.1 hypothetical protein -
  A66_RS02415 (A66_00482) - 458492..458830 (+) 339 WP_000682133.1 LytTR family DNA-binding domain-containing protein -
  A66_RS02420 (A66_00483) comE/blpR 458835..459572 (+) 738 WP_001219121.1 response regulator transcription factor Regulator
  A66_RS02425 (A66_00484) - 459586..460926 (+) 1341 WP_053039477.1 sensor histidine kinase -
  A66_RS02430 (A66_00485) blpC 460997..461125 (-) 129 WP_000358815.1 quorum-sensing system pheromone BlpC -

Sequence

Protein


Download         Length: 243 a.a.        Molecular weight: 27012.49 Da        Isoelectric Point: 4.7737

>NTDB_id=1114556 A66_RS02400 WP_000889919.1 456048..456779(+) (pptA) [Streptococcus pneumoniae strain A66]
MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTINEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIP
ETPSLYEELTLREHIETVAMAYGIEQKVAFERVEPLLKMFRLDQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQLREAFDMPEASLNDIYLALTKE
EDL

Nucleotide


Download         Length: 732 bp        

>NTDB_id=1114556 A66_RS02400 WP_000889919.1 456048..456779(+) (pptA) [Streptococcus pneumoniae strain A66]
ATGTTAGAAATTAAAAACCTGACAGGTGGCTATGTTCATGTTCCTGTTTTGAAAGATGTGTCCTTTACTGTTGAAAGTGG
GCAGTTGGTCGGTTTGATTGGTCTCAATGGTGCTGGGAAATCAACGACGATCAATGAGATTATCGGTCTGTTGGCACCTT
ATAGTGGCTCCATCAATATCAATGGCCTGACTCTGCAAGGAGATGCGACTAGCTACCGCAAGCAGATTGGCTACATTCCT
GAGACGCCTAGTCTGTATGAGGAATTGACCCTCAGAGAGCATATCGAAACGGTTGCTATGGCTTACGGTATTGAGCAAAA
AGTGGCTTTCGAACGAGTAGAGCCCTTGTTAAAGATGTTCCGTCTGGACCAGAAATTAGACTGGTTCCCTGTTCATTTTT
CAAAAGGGATGAAGCAGAAGGTCATGATTATCTGTGCTTTTGTGGTGGATCCAAGTCTTTTCATCGTGGATGAGCCTTTC
CTTGGTCTTGATCCGCTGGCTATTTCTGATTTGATTCAGCTTTTGGAAGTGGAGAAGCAAAAGGGCAAGTCTATTCTCAT
GAGTACCCACGTGCTGGATTCGGCGGAGAAGATGTGTGATGCCTTTGTCATTCTTCACAAGGGAGAGGTGCGTGCCAAAG
GCAATCTCCTGCAACTACGTGAAGCCTTTGATATGCCTGAGGCTAGTTTGAATGATATTTACTTGGCTCTGACCAAAGAG
GAGGATCTATGA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(17-160)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A062WNF5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pptA Streptococcus salivarius strain HSISS4

72.614

99.177

0.72
  pptA Streptococcus thermophilus LMD-9

71.784

99.177

0.712

Multiple sequence alignment