Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   A66_RS01800 Genome accession   NZ_LN847353
Coordinates   341478..342167 (+) Length   229 a.a.
NCBI ID   WP_053039450.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain A66     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 336478..347167
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A66_RS01775 (A66_00354) gpsB 336587..336916 (+) 330 WP_000146520.1 cell division regulator GpsB -
  A66_RS01785 (A66_00355) - 337402..338559 (+) 1158 WP_000711385.1 class I SAM-dependent RNA methyltransferase -
  A66_RS01790 (A66_00356) mapZ 338572..339966 (+) 1395 WP_053039449.1 mid-cell-anchored protein MapZ -
  A66_RS01795 (A66_00357) gndA 340042..341466 (+) 1425 WP_000158781.1 NADP-dependent phosphogluconate dehydrogenase -
  A66_RS01800 (A66_00358) covR 341478..342167 (+) 690 WP_053039450.1 response regulator transcription factor Regulator
  A66_RS01805 (A66_00359) cbpC 342265..343290 (+) 1026 WP_053039451.1 choline-binding protein CbpC -
  A66_RS01810 (A66_00360) - 343309..344184 (+) 876 WP_053039452.1 choline-binding protein CbpJ -
  A66_RS01815 (A66_00361) - 344302..345534 (-) 1233 WP_053039453.1 MFS transporter -
  A66_RS01820 (A66_00362) - 345577..346452 (-) 876 WP_010963214.1 lanthionine synthetase LanC family protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26908.24 Da        Isoelectric Point: 6.9836

>NTDB_id=1114554 A66_RS01800 WP_053039450.1 341478..342167(+) (covR) [Streptococcus pneumoniae strain A66]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLMLLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVLIENLVARISVIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTIQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=1114554 A66_RS01800 WP_053039450.1 341478..342167(+) (covR) [Streptococcus pneumoniae strain A66]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATGTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGTCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCCTTAT
CGAAAATCTGGTAGCGCGTATTTCGGTGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGTAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGATATACCATTCAAGAATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.826

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.217

100

0.454

Multiple sequence alignment